(Q37706181)

22 August 2017

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title

Immunopathologies linked to integrin signalling (English)

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22 August 2017

Hongyan Wang

1

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22 August 2017

Daina Lim

series ordinal

2

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22 August 2017

Christopher E Rudd

series ordinal

3

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22 August 2017

publication date

10 March 2010

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Seminars in Immunopathology

22 August 2017

published in

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22 August 2017

volume

32

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22 August 2017

issue

2

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22 August 2017

page(s)

173-182

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Regulation of beta 1 integrin-mediated adhesion by T cell receptor signaling involves ZAP-70 but differs from signaling events that regulate transcriptional activity

22 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00281-010-0202-3

Brief report: recurrent severe infections caused by a novel leukocyte adhesion deficiency

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00281-010-0202-3

LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00281-010-0202-3

The tail of integrins, talin, and kindlins

21 January 2018

1 reference

12 December 2020

Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domain

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12 December 2020

Compartmentalization of ITAM and integrin signaling by adapter molecules

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12 December 2020

Structural basis for the autoinhibition of talin in regulating integrin activation

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12 December 2020

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

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12 December 2020

Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation

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12 December 2020

Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion

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12 December 2020

Embryonic mesodermal defects in alpha 5 integrin-deficient mice

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12 December 2020

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

1 reference

12 December 2020

Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

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12 December 2020

SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55

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12 December 2020

FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

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12 December 2020

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

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12 December 2020

Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3.

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12 December 2020

FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells

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12 December 2020

An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R

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12 December 2020

SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility

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12 December 2020

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

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12 December 2020

Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion

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12 December 2020

Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions

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12 December 2020

The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1

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12 December 2020

Novel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production

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12 December 2020

Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking

1 reference

12 December 2020

Structural basis of integrin activation by talin

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12 December 2020

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

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12 December 2020

Integrin signalling at a glance

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12 December 2020

A novel targeted T-cell modulator, efalizumab, for plaque psoriasis

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12 December 2020

Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands

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12 December 2020

Chronic colitis due to an epithelial barrier defect: the role of kindlin-1 isoforms.

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12 December 2020

The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.

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12 December 2020

Kindlin-2 (Mig-2): a co-activator of beta3 integrins.

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12 December 2020

Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice

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12 December 2020

The phosphotyrosine binding-like domain of talin activates integrins

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12 December 2020

SKAP1 is dispensable for chemokine-induced migration of primary T-cells

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12 December 2020

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

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12 December 2020

Biochemical analysis of p120/130: a protein-tyrosine kinase substrate restricted to T and myeloid cells

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12 December 2020

Lymphocyte homing and homeostasis

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12 December 2020

An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding

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12 December 2020

Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab

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12 December 2020

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

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12 December 2020

Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome.

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12 December 2020

The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells

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12 December 2020

Kindlin-2 controls bidirectional signaling of integrins

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12 December 2020

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex

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12 December 2020

SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55

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12 December 2020

Integrins: bidirectional, allosteric signaling machines

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12 December 2020

Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

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12 December 2020

Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails

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12 December 2020

The Kindlins: subcellular localization and expression during murine development

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12 December 2020

Genetic and pharmacological analyses of Syk function in alphaIIbbeta3 signaling in platelets

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12 December 2020

Coupling of the TCR to integrin activation by Slap-130/Fyb.

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12 December 2020

Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling

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12 December 2020

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

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12 December 2020

Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses

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12 December 2020

ILK, PINCH and parvin: the tIPP of integrin signalling

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12 December 2020

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

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12 December 2020

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

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12 December 2020

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12 December 2020

Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.

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12 December 2020

Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors

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12 December 2020

Spontaneous skin ulceration and defective T cell function in CD18 null mice

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12 December 2020

SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates

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12 December 2020

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

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12 December 2020

T-cell integrins: more than just sticking points

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12 December 2020

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

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12 December 2020

Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130

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12 December 2020

Adaptors and molecular scaffolds in immune cell signaling

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12 December 2020

Transendothelial migration and trafficking of leukocytes in LFA-1-deficient mice

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12 December 2020

Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction

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12 December 2020

Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells

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12 December 2020

Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions

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12 December 2020

The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility.

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12 December 2020

Interplay between TCR signalling and actin cytoskeleton dynamics.

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12 December 2020

PRAM-1 is required for optimal integrin-dependent neutrophil function

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12 December 2020

Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

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12 December 2020

Syk is required for integrin signaling in neutrophils

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12 December 2020

The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter

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12 December 2020

LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor

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12 December 2020

Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells

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12 December 2020

Intracellular signalling controlling integrin activation in lymphocytes

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12 December 2020

Integrin activation and structural rearrangement

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12 December 2020

Structural basis of integrin regulation and signaling

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12 December 2020

Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion

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12 December 2020

Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development

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12 December 2020

Extracellular Ca2+ modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion

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12 December 2020

TEC-family kinases: regulators of T-helper-cell differentiation

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12 December 2020

In vivo functions of integrins: lessons from null mutations in mice

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12 December 2020

LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds

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12 December 2020

Kindlin-3 is essential for integrin activation and platelet aggregation

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12 December 2020

Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein

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12 December 2020

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality

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12 December 2020

SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils

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12 December 2020

Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells

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12 December 2020

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

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12 December 2020

RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation

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12 December 2020

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation

1 reference

12 December 2020

10.1007/S00281-010-0202-3

Identifiers

DOI

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22 August 2017

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