(Q37767172)

22 August 2017

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title

TNFα in myocardial ischemia/reperfusion, remodeling and heart failure (English)

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22 August 2017

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1

Petra Kleinbongard

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22 August 2017

Rainer Schulz

2

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PubMed ID

20571888

22 August 2017

Gerd Heusch

series ordinal

3

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22 August 2017

1 January 2011

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22 August 2017

Heart Failure Reviews

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22 August 2017

16

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22 August 2017

1

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22 August 2017

49-69

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https://scigraph.springernature.com/pub.10.1007/s10741-010-9180-8

22 August 2017

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cites work

Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology

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12 December 2020

Tumor necrosis factor-alpha produced in cardiomyocytes mediates a predominant myocardial inflammatory response to stretch in early volume overload

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12 December 2020

Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation

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12 December 2020

Sphingosine Mediates the Immediate Negative Inotropic Effects of Tumor Necrosis Factor-α in the Adult Mammalian Cardiac Myocyte

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12 December 2020

Endotoxin and ischemic preconditioning: TNF-alpha concentration and myocardial infarct development in rabbits

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12 December 2020

Coronary microembolization

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12 December 2020

HO-1 activation can attenuate cardiomyocytic apoptosis via inhibition of NF-kappaB and AP-1 translocation following cardiac global ischemia and reperfusion

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12 December 2020

Involvement of inducible nitric oxide synthase in cardiac dysfunction with tumor necrosis factor-alpha

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12 December 2020

Bidirectional role of tumor necrosis factor-alpha in coronary microembolization: progressive contractile dysfunction versus delayed protection against infarction.

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12 December 2020

Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST).

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12 December 2020

TNF-alpha is required for late ischemic preconditioning but not for remote preconditioning of trauma

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12 December 2020

Intracellular effects of nitric oxide on force production and Ca2+ sensitivity of cardiac myofilaments

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12 December 2020

Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning.

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12 December 2020

Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes

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12 December 2020

Tumor necrosis factor-alpha in macrophages of heart, liver, kidney, and in the pituitary gland.

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12 December 2020

Inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kappa B translocation and TNF alpha release

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12 December 2020

Pressure overload induces cardiac dysfunction and dilation in signal transducer and activator of transcription 6-deficient mice

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12 December 2020

1 reference

12 December 2020

Inhibition of target cell mitochondrial electron transfer by tumor necrosis factor

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12 December 2020

Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells

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12 December 2020

Tumor necrosis factor-alpha does not modulate ischemia/reperfusion injury in naïve myocardium but is essential for the development of late preconditioning

1 reference

12 December 2020

Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion

1 reference

12 December 2020

Plasma concentrations of TNF-alpha and its soluble receptors sTNFR1 and sTNFR2 in patients with coronary artery disease

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12 December 2020

Inhibition of tumor necrosis factor receptor-1-mediated pathways has beneficial effects in a murine model of postischemic remodeling.

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12 December 2020

Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene

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12 December 2020

Role of the innate immune system in acute viral myocarditis

1 reference

12 December 2020

Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice

1 reference

12 December 2020

Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL).

1 reference

12 December 2020

Postconditioning: old wine in a new bottle?

1 reference

12 December 2020

Cytokines and lipopolysaccharides induce inducible nitric oxide synthase but not enzyme activity in adult rat cardiomyocytes

1 reference

12 December 2020

Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum

1 reference

12 December 2020

Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha

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12 December 2020

Stimulation of alpha-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor.

1 reference

12 December 2020

Changes in cellular contractility and cytokines profile during Trypanosoma cruzi infection in mice

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12 December 2020

Mitogen-activated protein kinases in the heart

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12 December 2020

Physical activity and modulation of systemic low-level inflammation

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12 December 2020

Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging

1 reference

12 December 2020

Targeted Overexpression of Noncleavable and Secreted Forms of Tumor Necrosis Factor Provokes Disparate Cardiac Phenotypes

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12 December 2020

Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study

1 reference

12 December 2020

Nitric oxide provokes tumor necrosis factor-alpha expression in adult feline myocardium through a cGMP-dependent pathway

1 reference

12 December 2020

Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy

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12 December 2020

Differential expression of tissue inhibitors of metalloproteinases in the failing human heart

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12 December 2020

Matrix metalloproteinase-2 mediates cytokine-induced myocardial contractile dysfunction.

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12 December 2020

In vivo TNF-alpha inhibition ameliorates cardiac mitochondrial dysfunction, oxidative stress, and apoptosis in experimental heart failure

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12 December 2020

Elevated circulating levels of tumor necrosis factor in severe chronic heart failure

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12 December 2020

Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression.

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12 December 2020

Tumour necrosis factor-alpha uncouples respiration in isolated rat mitochondria.

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12 December 2020

Carvedilol, a nonselective beta-blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro

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12 December 2020

Physiological roles of muscle-derived interleukin-6 in response to exercise

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12 December 2020

Blockade of NF-kappaB by pyrrolidine dithiocarbamate attenuates myocardial inflammatory response and ventricular dysfunction following coronary microembolization induced by homologous microthrombi in rats

1 reference

12 December 2020

Reduced calcium responsiveness characterizes contractile dysfunction following coronary microembolization

1 reference

12 December 2020

Circulating concentrations of proinflammatory cytokines in mild or moderate heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Tumor necrosis factor in congestive heart failure: A mechanism of disease for the new millennium?

1 reference

12 December 2020

New insights into the pathological role of TNF-alpha in early cardiac dysfunction and subsequent heart failure after infarction in rats

1 reference

12 December 2020

Induction and potential biological relevance of a Ca(2+)-independent nitric oxide synthase in the myocardium

1 reference

12 December 2020

Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis

1 reference

12 December 2020

TNF-alpha-induced mitochondrial oxidative stress and cardiac dysfunction: restoration by superoxide dismutase mimetic Tempol

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12 December 2020

Regulation of proliferation, survival and apoptosis by members of the TNF superfamily

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12 December 2020

Comparison of tumor necrosis factor-alpha effect on the expression of iNOS in macrophage and cardiac myocytes

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12 December 2020

Silencing MR-1 attenuates inflammatory damage in mice heart induced by AngII

1 reference

12 December 2020

The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding

1 reference

12 December 2020

Inflammatory cytokines and the possible immunological role for lipoproteins in chronic heart failure.

1 reference

12 December 2020

Endogenous protective mechanisms in myocardial ischemia: hibernation and ischemic preconditioning

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12 December 2020

Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure

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12 December 2020

Myocardial hibernation: a delicate balance.

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12 December 2020

Coronary microembolization: from bedside to bench and back to bedside

1 reference

12 December 2020

The involvement of superoxide and iNOS-derived NO in cardiac dysfunction induced by pro-inflammatory cytokines

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12 December 2020

Effects of levo- and dextrosimendan on NF-kappaB-mediated transcription, iNOS expression and NO production in response to inflammatory stimuli.

1 reference

12 December 2020

Regulation of the human tumor necrosis factor-α promoter by angiotensin II and lipopolysaccharide in cardiac fibroblasts: different cis-acting promoter sequences and transcriptional factors

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12 December 2020

TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways

1 reference

12 December 2020

Effects of tumor necrosis factor gene polymorphisms on patients with congestive heart failure. VEST Investigators for TNF Genotype Analysis. Vesnarinone Survival Trial.

1 reference

12 December 2020

Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart

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12 December 2020

Inducible nitric oxide synthase expression and cardiomyocyte dysfunction during sustained moderate ischemia in pigs.

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12 December 2020

Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II

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12 December 2020

Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling

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12 December 2020

Hydrogen peroxide enhances shedding of type I soluble tumor necrosis factor receptor from pulmonary epithelial cells

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12 December 2020

Expression of inducible nitric oxide synthase in human heart failure

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12 December 2020

TNF-induced mitochondrial damage: a link between mitochondrial complex I activity and left ventricular dysfunction

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12 December 2020

TNFR1- and TNFR2-mediated signaling pathways in human kidney are cell type-specific and differentially contribute to renal injury

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12 December 2020

Calcium sensitivity, force frequency relationship and cardiac troponin I: critical role of PKA and PKC phosphorylation sites

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12 December 2020

TNF signaling in vascular endothelial cells

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12 December 2020

Pro-inflammatory cytokines and adipose tissue

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12 December 2020

Circulating levels of cytokines and their site of production in patients with mild to severe chronic heart failure

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12 December 2020

Tumor necrosis factor receptors 1 and 2 differentially regulate survival, cardiac dysfunction, and remodeling in transgenic mice with tumor necrosis factor-alpha-induced cardiomyopathy.

1 reference

12 December 2020

Cyclic adenosine monophosphate in acute myocardial infarction with heart failure: slayer or savior?

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12 December 2020

Physiology and pharmacology of myocardial preconditioning and postconditioning

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12 December 2020

Blockade of NF-kappaB improves cardiac function and survival without affecting inflammation in TNF-alpha-induced cardiomyopathy.

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12 December 2020

Regional differences of myocardial infarct development and ischemic preconditioning

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12 December 2020

A1 adenosine receptor upregulation accompanies decreasing myocardial adenosine levels in mice with left ventricular dysfunction

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12 December 2020

MMP inhibition modulates TNF-alpha transgenic mouse phenotype early in the development of heart failure

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12 December 2020

The role of inflammatory mediators in chronic heart failure: cytokines, nitric oxide, and endothelin-1.

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12 December 2020

Effects of therapy using the Celacade system on structural and functional cardiac remodelling in rats following myocardial infarction

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12 December 2020

Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction

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12 December 2020

Circulating cytokine levels in mice with heart failure are etiology dependent

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12 December 2020

Histone deacetylase-3 activation promotes tumor necrosis factor-alpha (TNF-alpha) expression in cardiomyocytes during lipopolysaccharide stimulation

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12 December 2020

Release of TNF-alpha during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers

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12 December 2020

Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning

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12 December 2020

NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha

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12 December 2020

The cytoprotective effects of tumor necrosis factor are conveyed through tumor necrosis factor receptor-associated factor 2 in the heart

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12 December 2020

Plasma cytokine parameters and mortality in patients with chronic heart failure

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12 December 2020

Effects of inhibition of nitric oxide synthesis on TNF alpha serum levels in E. coli endotoxemic rats.

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12 December 2020

Common community infections and the risk for coronary artery disease and acute myocardial infarction: evidence for chronic over-expression of tumor necrosis factor alpha and vascular cells adhesion molecule-1.

1 reference

12 December 2020

The relationship between cholesterol and survival in patients with chronic heart failure

1 reference

12 December 2020

Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis

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12 December 2020

Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction

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12 December 2020

Insights from knock-out models concerning postischemic release of TNFalpha from isolated mouse hearts

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12 December 2020

TNF-alpha antibodies are as effective as ischemic preconditioning in reducing infarct size in rabbits

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12 December 2020

Adenosine prevents activation of transcription factor NF-kappa B and enhances activator protein-1 binding activity in ischemic rat heart

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12 December 2020

Case reports of heart failure after therapy with a tumor necrosis factor antagonist

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12 December 2020

Differential effects of amrinone and milrinone upon myocardial inflammatory signaling.

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12 December 2020

Tumor necrosis factor-alpha converting enzyme

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12 December 2020

Innate immunity and myocardial adaptation to ischemia

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12 December 2020

TNF receptors differentially signal and are differentially expressed and regulated in the human heart.

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12 December 2020

The anti-inflammatory effect of exercise

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12 December 2020

Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway

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12 December 2020

The immune system and cardiac repair.

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12 December 2020

1 reference

12 December 2020

Selective decrease in cell surface expression and mRNA level of the 55-kDa tumor necrosis factor receptor during differentiation of HL-60 cells into macrophage-like but not granulocyte-like cells

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12 December 2020

The role of TNF-alpha receptors p55 and p75 in acute myocardial ischemia/reperfusion injury and late preconditioning

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12 December 2020

Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production.

1 reference

12 December 2020

Endotoxin-Induced Myocardial Tumor Necrosis Factor-α Synthesis Depresses Contractility of Isolated Rat Hearts

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12 December 2020

The role of ceramide in cell signaling

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12 December 2020

Endothelial activation by hydrogen peroxide. Selective increases of intercellular adhesion molecule-1 and major histocompatibility complex class I.

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12 December 2020

Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice

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12 December 2020

Pathophysiologic quantities of endotoxin-induced tumor necrosis factor-alpha release in whole blood from patients with chronic heart failure

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12 December 2020

Regulating RISK: a role for JAK-STAT signaling in postconditioning?

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12 December 2020

Histamine antagonizes tumor necrosis factor (TNF) signaling by stimulating TNF receptor shedding from the cell surface and Golgi storage pool

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12 December 2020

Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis

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12 December 2020

Effect of tumor necrosis factor-alpha on endothelial and inducible nitric oxide synthase messenger ribonucleic acid expression and nitric oxide synthesis in ischemic and nonischemic isolated rat heart.

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12 December 2020

Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection

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12 December 2020

Ageing, tumour necrosis factor-alpha (TNF-alpha) and atherosclerosis

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12 December 2020

Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy

1 reference

12 December 2020

Tumor necrosis factor-alpha is expressed by monocytes/macrophages following cardiac microembolization and is antagonized by cyclosporine

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12 December 2020

Results of a non-specific immunomodulation therapy in chronic heart failure (ACCLAIM trial): a placebo-controlled randomised trial.

1 reference

12 December 2020

TNFR1 and TNFR2 signaling interplay in cardiac myocytes.

1 reference

12 December 2020

Circulating TNFR1 exosome-like vesicles partition with the LDL fraction of human plasma

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12 December 2020

Inflammatory cytokines in heart failure: roles in aetiology and utility as biomarkers

1 reference

12 December 2020

Coronary microembolization: the role of TNF-alpha in contractile dysfunction

1 reference

12 December 2020

Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration

1 reference

12 December 2020

Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Baseline low-density lipoprotein cholesterol levels and outcome in patients with heart failure

1 reference

12 December 2020

Plasma concentrations of tumour necrosis factor-alpha, tumour necrosis factor-related apoptosis-inducing ligand, and FasLigand/CD95L in patients with Chagas cardiomyopathy correlate with left ventricular dysfunction.

1 reference

12 December 2020

Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction

1 reference

12 December 2020

Cloning and characterization of human TNF alpha promoter region.

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12 December 2020

Abnormal cardiac and skeletal muscle mitochondrial function in pacing-induced cardiac failure

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12 December 2020

TNF-alpha inhibition attenuates adverse myocardial remodeling in a rat model of volume overload

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12 December 2020

Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failu

1 reference

12 December 2020

The emerging role of the gut in chronic heart failure

1 reference

12 December 2020

Innate immunity and the heart

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12 December 2020

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

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12 December 2020

Cytokine-induced modulation of cardiac function

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12 December 2020

Ischemic preconditioning or p38 MAP kinase inhibition attenuates myocardial TNF alpha production and mitochondria damage in brief myocardial ischemia

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12 December 2020

Immune function in sport and exercise

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12 December 2020

Cloning and partial characterization of the promoter for the human p55 tumor necrosis factor (TNF) receptor.

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12 December 2020

Signal transduction of ischemic preconditioning

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12 December 2020

Serum but not myocardial TNF-α concentration is increased in pacing-induced heart failure in rabbits

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12 December 2020

Inflammation and atherosclerosis

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12 December 2020

Polymorphisms of tumor necrosis factor-alpha and interleukin-10 genes in Japanese patients with idiopathic dilated cardiomyopathy

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12 December 2020

Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness

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12 December 2020

Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway

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12 December 2020

TNFalpha in atherosclerosis, myocardial ischemia/reperfusion and heart failure

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12 December 2020

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

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12 December 2020

Clinical implications of inflammation for cardiovascular primary prevention

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12 December 2020

The sphingomyelin cycle and the second messenger function of ceramide.

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12 December 2020

Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning

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12 December 2020

Tumor Necrosis Factor Soluble Receptors in Patients With Various Degrees of Congestive Heart Failure

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12 December 2020

Endotoxin and cytokines alter contractile protein expression in cardiac myocytes in vivo

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12 December 2020

Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: role of nuclear factor-kappaB and inflammatory activation

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12 December 2020

The mitochondrial permeability transition pore and the Ca2+-activated K+ channel contribute to the cardioprotection conferred by tumor necrosis factor-alpha

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12 December 2020

Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes

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12 December 2020

IL-1 inhibits beta-adrenergic control of cardiac calcium current: role of L-arginine/nitric oxide pathway

1 reference

12 December 2020

Plasma levels of TNF-alpha, IL-6, and IL-10 and their relationship with left ventricular diastolic function in patients with stable angina pectoris and preserved left ventricular systolic performance

1 reference

12 December 2020

The immune system and chronic heart failure: is the heart in control?

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12 December 2020

Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3Kgamma-dependent manner

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12 December 2020

Role of tumor necrosis factor alpha and its receptor I in preconditioning by hyperoxia

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12 December 2020

Excessive Tumor Necrosis Factor Activation After Infarction Contributes to Susceptibility of Myocardial Rupture and Left Ventricular Dysfunction

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12 December 2020

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

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12 December 2020

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

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12 December 2020

Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy

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12 December 2020

Tumor necrosis factor-induced protection of the murine heart is independent of p38-MAPK activation.

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12 December 2020

Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor

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12 December 2020

Increased production of tumor necrosis factor and interleukin-6 by arterial wall of aged rats

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12 December 2020

Oxidative stress promotes ligand-independent and enhanced ligand-dependent tumor necrosis factor receptor signaling

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12 December 2020

An endotoxin-induced serum factor that causes necrosis of tumors

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12 December 2020

Targeted overexpression of transmembrane tumor necrosis factor provokes a concentric cardiac hypertrophic phenotype.

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12 December 2020

Safety and efficacy of a soluble P75 tumor necrosis factor receptor (Enbrel, etanercept) in patients with advanced heart failure.

1 reference

12 December 2020

Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure

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12 December 2020

IL-1beta and TNF-alpha upregulate angiotensin II type 1 (AT1) receptors on cardiac fibroblasts and are associated with increased AT1 density in the post-MI heart

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12 December 2020

Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha

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12 December 2020

Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart

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12 December 2020

TNF-alpha-mediated cardiomyocyte apoptosis involves caspase-12 and calpain

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12 December 2020

The importance of the gastrointestinal system in the pathogenesis of heart failure

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12 December 2020

WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte death

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12 December 2020

Survival pathways in hypertrophy and heart failure: the gp130-STAT axis

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12 December 2020

Definition of a new score for severity of generalizedNeisseria meningitidis infection

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12 December 2020

Tumour necrosis factor in chronic heart failure: a peripheral view on pathogenesis, clinical manifestations and therapeutic implications

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12 December 2020

Altered signalling and gene expression associated with the immune system and the inflammatory response in obesity

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12 December 2020

Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy

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12 December 2020

Characterization of tumor necrosis factor-deficient mice

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12 December 2020

Inflammation in atherosclerosis

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12 December 2020

Tumor necrosis factor-alpha induces a biphasic effect on myocardial contractility in conscious dogs

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12 December 2020

Nitric oxide-dependent and -independent mechanisms are involved in TNF-alpha -induced depression of cardiac myocyte contractility

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12 December 2020

Oxidative modification of tropomyosin and myocardial dysfunction following coronary microembolization

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12 December 2020

Mitochondrial Ca(2+)homeostasis in the regulation of apoptotic and necrotic cell deaths

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12 December 2020

Inflammation: the link between insulin resistance, obesity and diabetes

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12 December 2020

Revisiting the role of tumor necrosis factor alpha and the response to surgical injury and inflammation.

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12 December 2020

Tumor necrosis factor (TNF) up-regulates the expression of p75 but not p55 TNF receptors, and both receptors mediate, independently of each other, up-regulation of transforming growth factor alpha and epidermal growth factor receptor mRNA

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12 December 2020

Inhibition of mitochondrial permeability transition pore opening: the Holy Grail of cardioprotection

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12 December 2020

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

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12 December 2020

Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning

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12 December 2020

Genomic organization and promoter function of the murine tumor necrosis factor receptor beta gene

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12 December 2020

Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha

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12 December 2020

Inflammatory process in type 2 diabetes: The role of cytokines.

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12 December 2020

Selective intestinal decontamination in advanced chronic heart failure: a pilot trial

1 reference

12 December 2020

Tumor necrosis factor antagonist mechanisms of action: a comprehensive review

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12 December 2020

Tumor necrosis factor-alpha and its receptors 1 and 2: Yin and Yang in myocardial infarction?

1 reference

12 December 2020

The myocardial JAK/STAT pathway: from protection to failure

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12 December 2020

Cardioprotection: nitric oxide, protein kinases, and mitochondria

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12 December 2020

Elevated plasma levels of TNF-alpha and interleukin-6 in patients with diastolic dysfunction and glucose metabolism disorders

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12 December 2020

Analysis of the cytokine-stimulated human inducible nitric oxide synthase (iNOS) gene: characterization of differences between human and mouse iNOS promoters.

1 reference

12 December 2020

Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region

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12 December 2020

Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes

1 reference

12 December 2020

Neutrophils contribute to TNF induced myocardial tolerance to ischaemia

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12 December 2020

Selective up-regulation of the 75-kDa tumor necrosis factor (TNF) receptor and its mRNA by TNF and IL-1

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12 December 2020

Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction

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12 December 2020

Apoptosis-inducing agents cause rapid shedding of tumor necrosis factor receptor 1 (TNFR1). A nonpharmacological explanation for inhibition of TNF-mediated activation

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12 December 2020

Influence of metabolic syndrome on biomarkers of oxidative stress and inflammation in obese adults

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12 December 2020

Role of STAT3 in ischemic preconditioning

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12 December 2020

Transcriptional regulation of inducible nitric oxide synthase in cultured neonatal rat cardiac myocytes

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12 December 2020

Results of targeted anti-tumor necrosis factor therapy with etanercept (ENBREL) in patients with advanced heart failure

1 reference

12 December 2020

Immune modulation: role of the inflammatory cytokine cascade in the failing human heart

1 reference

12 December 2020

Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes

1 reference

12 December 2020

Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression

1 reference

12 December 2020

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

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12 December 2020

Cytokines are not a requisite part of the pathophysiology leading to cardiac decompensation

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12 December 2020

Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization

1 reference

12 December 2020

The time course of cardiac NF-kappaB activation and TNF-alpha secretion by cardiac myocytes after burn injury: contribution to burn-related cardiac contractile dysfunction

1 reference

12 December 2020

Cellular basis for the acute inhibitory effects of IL-6 and TNF- alpha on excitation-contraction coupling

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12 December 2020

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

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12 December 2020

Inhibition of TNF-alpha reduces myocardial injury and proinflammatory pathways following ischemia-reperfusion in the dog

1 reference

12 December 2020

Free radicals trigger TNF alpha-induced cardioprotection

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12 December 2020

Genetic variation associated with ischemic heart failure: a HuGE review and meta-analysis

1 reference

12 December 2020

Cardiac inflammation and innate immunity in septic shock: is there a role for toll-like receptors?

1 reference

12 December 2020

FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK.

1 reference

12 December 2020

Tumor necrosis factor-alpha is toxic via receptor 1 and protective via receptor 2 in a murine model of myocardial infarction

1 reference

12 December 2020

A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure

1 reference

12 December 2020

Aging and proinflammatory cytokines

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12 December 2020

Complement and dilated cardiomyopathy: a role of sublytic terminal complement complex-induced tumor necrosis factor-alpha synthesis in cardiac myocytes

1 reference

12 December 2020

Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase).

1 reference

12 December 2020

Antioxidant amelioration of dilated cardiomyopathy caused by conditional deletion of NEMO/IKKgamma in cardiomyocytes.

1 reference

12 December 2020

Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats

1 reference

12 December 2020

Immune activation in chronic heart failure

1 reference

12 December 2020

Tumor necrosis factor-alpha decreases sarcoplasmic reticulum Ca2+-ATPase expressions via the promoter methylation in cardiomyocytes

1 reference

12 December 2020

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

1 reference

12 December 2020

c-Fos suppresses systemic inflammatory response to endotoxin

1 reference

12 December 2020

Tumor necrosis factor-alpha receptor 1 is a major predictor of mortality and new-onset heart failure in patients with acute myocardial infarction: the Cytokine-Activation and Long-Term Prognosis in Myocardial Infarction (C-ALPHA) study

1 reference

12 December 2020

Myocardial dysfunction with coronary microembolization: signal transduction through a sequence of nitric oxide, tumor necrosis factor-alpha, and sphingosine

1 reference

12 December 2020

Tumor necrosis factor-α in the failing human heart: Does it play a role in disease progression?

1 reference

12 December 2020

Sphingosine modulates myocyte electrophysiology, induces negative inotropy, and decreases survival after myocardial ischemia

1 reference

12 December 2020

Tumor necrosis factor-alpha provokes a hypertrophic growth response in adult cardiac myocytes

1 reference

12 December 2020

In vivo transfer of soluble TNF-alpha receptor 1 gene improves cardiac function and reduces infarct size after myocardial infarction in rats

1 reference

12 December 2020

Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun

1 reference

12 December 2020

Hemodynamic regulation of tumor necrosis factor-alpha gene and protein expression in adult feline myocardium

1 reference

12 December 2020

Induction of iNOS expression in skeletal muscle by IL-1beta and NFkappaB activation: an in vitro and in vivo study

1 reference

12 December 2020

The role of ADAM protease in the tyrosine kinase-mediated trigger mechanism of ischemic preconditioning

1 reference

12 December 2020

(Un)expected roles of c-IAPs in apoptotic and NFkappaB signaling pathways

1 reference

12 December 2020

Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?

1 reference

12 December 2020

Differential effect of oxpentifylline on tumour necrosis factor and interleukin-6 production

1 reference

12 December 2020

TNF-mediated inflammatory disease.

1 reference

12 December 2020

Cytokine mRNA expression in postischemic/reperfused myocardium.

1 reference

12 December 2020

TNF-alpha-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes

1 reference

12 December 2020

Lactic acidosis increases tumor necrosis factor secretion and transcription in vitro

1 reference

12 December 2020

C-reactive protein, interleukin-6 and tumor necrosis factor alpha as predictors of incident coronary and cardiovascular events and total mortality. A population-based, prospective study

1 reference

12 December 2020

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

12 December 2020

Native and reconstituted HDL activate Stat3 in ventricular cardiomyocytes via ERK1/2: role of sphingosine-1-phosphate

1 reference

12 December 2020

Ischemic postconditioning in pigs: no causal role for RISK activation.

1 reference

12 December 2020

10.1007/S10741-010-9180-8

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20571888