(Q37785298)

23 August 2017

title

BACE: Therapeutic target and potential biomarker for Alzheimer's disease (English)

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23 August 2017

0 references

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3

Colin L Masters

1 reference

23 August 2017

Geneviève Evin

1

1 reference

23 August 2017

Adel Barakat

2

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23 August 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20817005

6 July 2024

publication date

15 September 2010

1 reference

full work available at URL

23 August 2017

https://api.elsevier.com/content/article/PII:S1357272510002992?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BIOCEL.2010.08.017

https://api.elsevier.com/content/article/PII:S1357272510002992?httpAccept=text/plain

6 July 2024

1 reference

https://api.crossref.org/works/10.1016/J.BIOCEL.2010.08.017

International Journal of Biochemistry & Cell Biology

6 July 2024

published in

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23 August 2017

volume

42

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23 August 2017

issue

12

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23 August 2017

page(s)

1923-1926

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

23 August 2017

cites work

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6 July 2024

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A splice variant of beta-secretase deficient in the amyloidogenic processing of the amyloid precursor protein

6 July 2024

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Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein

6 July 2024

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BACE inhibitors as potential therapeutics for Alzheimer's disease

6 July 2024

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Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets

6 July 2024

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Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

6 July 2024

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Beta-secretase activity increases with aging in human, monkey, and mouse brain.

6 July 2024

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BACE1 (beta-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes

6 July 2024

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GGA proteins mediate the recycling pathway of memapsin 2 (BACE).

6 July 2024

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Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

6 July 2024

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Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor

6 July 2024

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Bace1 modulates myelination in the central and peripheral nervous system.

6 July 2024

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BACE1 deficiency causes altered neuronal activity and neurodegeneration

6 July 2024

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Cell biology, regulation and inhibition of beta-secretase (BACE-1).

6 July 2024

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

6 July 2024

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Ubiquitin regulates GGA3-mediated degradation of BACE1

6 July 2024

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Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

6 July 2024

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Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway

6 July 2024

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Promotion of BACE1 mRNA alternative splicing reduces amyloid beta-peptide production

6 July 2024

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BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

6 July 2024

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Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice

6 July 2024

23

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Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model

6 July 2024

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Understanding BACE1: essential protease for amyloid-beta production in Alzheimer's disease.

6 July 2024

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The beta-secretase, BACE: a prime drug target for Alzheimer's disease

6 July 2024

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

6 July 2024

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The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

6 July 2024

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Control of amyloid-beta-peptide generation by subcellular trafficking of the beta-amyloid precursor protein and beta-secretase

6 July 2024

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Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

6 July 2024

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6 July 2024

Identifiers

1 reference

23 August 2017

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