(Q37809967)

23 August 2017

title

Fundamental functionality: recent developments in understanding the structure-activity relationships of lantibiotic peptides (English)

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23 August 2017

author

John Christopher Vederas

series ordinal

2

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author name string

Avena C Ross

series ordinal

1

1 reference

23 August 2017

publication date

17 November 2010

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The Journal of Antibiotics

23 August 2017

published in

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23 August 2017

volume

64

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23 August 2017

issue

1

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23 August 2017

page(s)

27-34

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https://scigraph.springernature.com/pub.10.1038/ja.2010.136

23 August 2017

exact match

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cites work

Drug discovery and natural products: end of an era or an endless frontier?

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In vitro and in vivo evaluation of A-56268 (TE-031), a new macrolide

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Lantibiotics: peptides of diverse structure and function.

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Biosynthesis and mode of action of lantibiotics.

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Bacterial lantibiotics: strategies to improve therapeutic potential.

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Insights into the mode of action of the two-peptide lantibiotic haloduracin

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Oxidation of lanthionines renders the lantibiotic nisin inactive.

21 January 2018

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Lantibiotics: diverse activities and unique modes of action

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Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin

21 January 2018

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Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation

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The generation of nisin variants with enhanced activity against specific gram-positive pathogens.

21 January 2018

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Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity

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Maturation by LctT is required for biosynthesis of full-length lantibiotic lacticin 481.

21 January 2018

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New developments in lantibiotic biosynthesis and mode of action.

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Structure-activity relationship studies of the two-component lantibiotic haloduracin

21 January 2018

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Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin

21 January 2018

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Dissecting structural and functional diversity of the lantibiotic mersacidin

21 January 2018

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Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase.

21 January 2018

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The biology of lantibiotics from the lacticin 481 group is coming of age.

21 January 2018

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Bacteriocin detection from whole bacteria by matrix-assisted laser desorption ionization-time of flight mass spectrometry

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In vitro mutasynthesis of lantibiotic analogues containing nonproteinogenic amino acids

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A novel lantibiotic, nukacin ISK-1, of Staphylococcus warneri ISK-1: cloning of the structural gene and identification of the structure

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Mersacidin eradicates methicillin-resistant Staphylococcus aureus (MRSA) in a mouse rhinitis model.

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Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

21 January 2018

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Developing applications for lactococcal bacteriocins

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Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147

21 January 2018

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Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design.

21 January 2018

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Solid-supported synthesis and biological evaluation of the lantibiotic peptide bis(desmethyl) lacticin 3147 A2.

21 January 2018

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Fracturing rings to understand lantibiotics

21 January 2018

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The mode of action of the lantibiotic lacticin 3147--a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II

21 January 2018

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7 January 2021

Cloning, expression, and nucleotide sequence of genes involved in production of lactococcin DR, a bacteriocin from lactococcus lactis subsp. lactis.

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https://api.crossref.org/works/10.1038%2FJA.2010.136

7 January 2021

Purification and Partial Characterization of Lacticin 481, a Lanthionine-Containing Bacteriocin Produced by Lactococcus lactis subsp. lactis CNRZ 481

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.136

7 January 2021

Mersacidin, a new antibiotic from Bacillus. Fermentation, isolation, purification and chemical characterization

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7 January 2021

Mersacidin, a new antibiotic from Bacillus. In vitro and in vivo antibacterial activity

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https://api.crossref.org/works/10.1038%2FJA.2010.136

7 January 2021

The lantibiotic mersacidin inhibits peptidoglycan synthesis by targeting lipid II.

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https://api.crossref.org/works/10.1038%2FJA.2010.136

7 January 2021

An application in cheddar cheese manufacture for a strain of Lactococcus lactis producing a novel broad-spectrum bacteriocin, lacticin 3147.

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.136

7 January 2021

A system for the random mutagenesis of the two-peptide lantibiotic lacticin 3147: analysis of mutants producing reduced antibacterial activities

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.136

7 January 2021

Synthesis and Biological Activity of Oxa-Lacticin A2, a Lantibiotic Analogue with Sulfur Replaced by Oxygen

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.136

7 January 2021

Multiple On-Resin Olefin Metathesis to Form Ring-Expanded Analogues of the Lantibiotic Peptide, Lacticin 3147 A2

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.136

7 January 2021

Identifiers

DOI

10.1038/JA.2010.136

1 reference

Dimensions Publication ID

23 August 2017

1037072964

0 references

1 reference