(Q37811027)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

The dawning of a 'Golden era' in lantibiotic bioengineering (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Colin Hill

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Des Field

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Reynolds Paul Ross

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Des Field

1

1 reference

23 August 2017

R Paul Ross

4

1 reference

23 August 2017

language of work or name

English

0 references

publication date

12 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

published in

Molecular Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

78

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

1077-1087

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21091497%20AND%20SRC:MED&resulttype=core&format=json

Dissecting structural and functional diversity of the lantibiotic mersacidin

16 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Distinct contributions of the nisin biosynthesis enzymes NisB and NisC and transporter NisT to prenisin production by Lactococcus lactis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Lantibiotics: mode of action, biosynthesis and bioengineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Organization of the genes encoding the biosynthesis of actagardine and engineering of a variant generation system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Insights into in vivo activities of lantibiotics from gallidermin and epidermin mode-of-action studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Lipid II as a target for antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Nisin, alone and combined with peptidoglycan-modulating antibiotics: activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

A novel lantibiotic acting on bacterial cell wall synthesis produced by the uncommon actinomycete Planomonospora sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Biosynthesis and mode of action of lantibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Structure-activity relationship studies of the two-component lantibiotic haloduracin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Bacterial lantibiotics: strategies to improve therapeutic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Manipulation of charged residues within the two-peptide lantibiotic lacticin 3147.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Thiol-disulfide oxidoreductases are essential for the production of the lantibiotic sublancin 168.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

The generation of nisin variants with enhanced activity against specific gram-positive pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Studies with bioengineered Nisin peptides highlight the broad-spectrum potency of Nisin V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

In vitro reconstitution and substrate specificity of a lantibiotic protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Bacteriocin-based strategies for food biopreservation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Microbial antagonists to food-borne pathogens and biocontrol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Lacticin 3147 displays activity in buffer against gram-positive bacterial pathogens which appear insensitive in standard plate assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Macedocin, a food-grade lantibiotic produced by Streptococcus macedonicus ACA-DC 198

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Inhalation of Moli1901 in patients with cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Isolation and identification of a Paenibacillus polymyxa strain that coproduces a novel lantibiotic and polymyxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Combination of antibiotic mechanisms in lantibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Evaluation of essential and variable residues of nukacin ISK-1 by NNK scanning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

SapT, a lanthionine-containing peptide involved in aerial hyphae formation in the streptomycetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Protein engineering of lantibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Sec-mediated transport of posttranslationally dehydrated peptides in Lactococcus lactis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Mechanistic dissection of the enzyme complexes involved in biosynthesis of lacticin 3147 and nisin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Translocation of a thioether-bridged azurin peptide fragment via the sec pathway in Lactococcus lactis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Two-peptide lantibiotics: a medical perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Use of lantibiotic synthetases for the preparation of bioactive constrained peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

In vitro mutasynthesis of lantibiotic analogues containing nonproteinogenic amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Investigation of the substrate specificity of lacticin 481 synthetase by using nonproteinogenic amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Identification of essential catalytic residues of the cyclase NisC involved in the biosynthesis of nisin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Influence of shifting positions of Ser, Thr, and Cys residues in prenisin on the efficiency of modification reactions and on the antimicrobial activities of the modified prepeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

The flavoprotein MrsD catalyzes the oxidative decarboxylation reaction involved in formation of the peptidoglycan biosynthesis inhibitor mersacidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Labyrinthopeptins: a new class of carbacyclic lantibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Nucleotide sequence of the lantibiotic Pep5 biosynthetic gene cluster and functional analysis of PepP and PepC. Evidence for a role of PepC in thioether formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

MICs of mutacin B-Ny266, nisin A, vancomycin, and oxacillin against bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Activity of mersacidin, a novel peptide, compared with that of vancomycin, teicoplanin, and daptomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

The application of a fermented food ingredient containing 'variacin', a novel antimicrobial produced by Kocuria varians, to control the growth of Bacillus cereus in chilled dairy products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Insights into the mode of action of the two-peptide lantibiotic haloduracin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

The importance of the leader sequence for directing lanthionine formation in lacticin 481.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Discovery of medically significant lantibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

A comparison of the activities of lacticin 3147 and nisin against drug-resistant Staphylococcus aureus and Enterococcus species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Production of dehydroamino acid-containing peptides by Lactococcus lactis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

To protect peptide pharmaceuticals against peptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Preservation and fermentation: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Biosynthesis and biological activities of lantibiotics with unique post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

The lantibiotic mersacidin is an autoinducing peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Biosynthesis of lantibiotic nisin. Posttranslational modification of its prepeptide occurs at a multimeric membrane-associated lanthionine synthetase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Gardimycin, a New Antibiotic Inhibiting Peptidoglycan Synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

AmfS, an extracellular peptidic morphogen in Streptomyces griseus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Lantibiotic biosynthesis: interactions between prelacticin 481 and its putative modification enzyme, LctM

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Streptococcal bacteriocins and the case for Streptococcus salivarius as model oral probiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Lipid II-based antimicrobial activity of the lantibiotic plantaricin C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Lantibiotics: peptides of diverse structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Heterologous expression and purification of SpaB involved in subtilin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

Site-directed mutagenesis of the hinge region of nisinZ and properties of nisinZ mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X

The three-dimensional solution structure of the lantibiotic murein-biosynthesis-inhibitor actagardine determined by NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2010.07406.X