(Q37834642)

24 August 2017

1 reference

title

The phosphoprotein phosphatase family of Ser/Thr phosphatases as principal targets of naturally occurring toxins (English)

1 reference

24 August 2017

3

1 reference

24 August 2017

Susana R Pereira

1

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Vitor Vasconcelos

object named as

Vítor M Vasconcelos

series ordinal

2

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language of work or name

English

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publication date

1 February 2011

1 reference

Critical Reviews in Toxicology

24 August 2017

published in

1 reference

24 August 2017

volume

41

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24 August 2017

issue

2

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24 August 2017

page(s)

83-110

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Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation

24 August 2017

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Protein tyrosine phosphatases in the human genome

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Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein

21 January 2018

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Dynamics of microcystins in the mussel Mytilus galloprovincialis

21 January 2018

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21 January 2018

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PPP family of protein Ser/Thr phosphatases: two distinct branches?

21 January 2018

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An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae

21 January 2018

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Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin

21 January 2018

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Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

21 January 2018

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Total synthesis and biological evaluation of the protein phosphatase 2A inhibitor cytostatin and analogues

21 January 2018

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The tetratricopeptide repeat: a structural motif mediating protein-protein interactions

21 January 2018

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Total synthesis of fostriecin (CI-920).

21 January 2018

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Functional diversity of protein phosphatase-1, a cellular economizer and reset button

21 January 2018

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Alpha 4 associates with protein phosphatases 2A, 4, and 6

21 January 2018

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Targeting of a distinctive protein-serine phosphatase to the protein kinase-like domain of the atrial natriuretic peptide receptor

21 January 2018

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Protein phosphatase 5 in signal transduction.

21 January 2018

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The regulation of protein function by multisite phosphorylation--a 25 year update

21 January 2018

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Okadaic acid: a new probe for the study of cellular regulation

21 January 2018

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Novel protein serine/threonine phosphatases: variety is the spice of life

21 January 2018

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Protein phosphatase 4--from obscurity to vital functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Importance of the β12-β13 Loop in Protein Phosphatase-1 Catalytic Subunit for Inhibition by Toxins and Mammalian Protein Inhibitors

21 January 2018

1 reference

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The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions

21 January 2018

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The toxicology of microcystins

21 January 2018

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Protein tyrosine phosphatases: mechanisms of catalysis and regulation

21 January 2018

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Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

21 January 2018

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Protein phosphatase 2A regulatory subunits and cancer.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Hepatocellular uptake of 3H-dihydromicrocystin-LR, a cyclic peptide toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

The predicted beta12-beta13 loop is important for inhibition of PP2Acalpha by the antitumor drug fostriecin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Arabidopsis PPP family of serine/threonine phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Importance of the C28-C38 hydrophobic domain of okadaic acid for potent inhibition of protein serine-threonine phosphatases 1 and 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Inhibition of protein serine/threonine phosphatases by fumonisin B1, a mycotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

A model for binding of structurally diverse natural product inhibitors of protein phosphatases PP1 and PP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Inhibition of several protein phosphatases by a non-covalently interacting microcystin and a novel cyanobacterial peptide, nostocyclin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Docking motif-guided mapping of the interactome of protein phosphatase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Regulators of serine/threonine protein phosphatases at the dawn of a clinical era?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Molecular cloning, expression, and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

A structural basis for the reduced toxicity of dinophysistoxin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Structure and mechanism of RNA polymerase II CTD phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Identification of amino acids in the tetratricopeptide repeat and C-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Differential induction of apoptosis in B16 melanoma and EL-4 lymphoma cells by cytostatin and bactobolin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure-based Drug Design of Serine/Threonine Phosphatase Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Archaeal protein kinases and protein phosphatases: insights from genomics and biochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Carboxymethylation of nuclear protein serine/threonine phosphatase X

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Purification and identification of a novel subunit of protein serine/threonine phosphatase 4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Post-translational generation of constitutively active cores from larger phosphatases in the malaria parasite, Plasmodium falciparum: implications for proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Protein Ser/Thr phosphatases PPEF interact with calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Fostriecin: chemistry and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Inhibitors of protein kinases and phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Evolution of protein kinase signaling from yeast to man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Thyrsiferyl 23-acetate is a novel specific inhibitor of protein phosphatase PP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

A structural perspective of CTD function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Tautomycetin is a novel and specific inhibitor of serine/threonine protein phosphatase type 1, PP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Cantharidin revisited: a blistering defense of an ancient medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Evolution of protein phosphatases in plants and animals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Permeability of a non-TPA-type tumor promoter, okadaic acid, through lipid bilayer membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Expression of the B56delta subunit of protein phosphatase 2A and Mea1 in mouse spermatogenesis. Identification of a new B56gamma subunit (B56gamma4) specifically expressed in testis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

The alpha4 regulatory subunit exerts opposing allosteric effects on protein phosphatases PP6 and PP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Identification of potential physiological activators of protein phosphatase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Phylogenetic evidence for the early evolution of microcystin synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Microcystin uptake and inhibition of protein phosphatases: effects of chemoprotectants and self-inhibition in relation to known hepatic transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

In vivo and in vitro binding of microcystin to protein phosphatases 1 and 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Characterization of the PP2A alpha gene mutation in okadaic acid-resistant variants of CHO-K1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Evolution of the metazoan protein phosphatase 2C superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

A gene atlas of the mouse and human protein-encoding transcriptomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Structure-activity relationship studies of fostriecin, cytostatin, and key analogs, with PP1, PP2A, PP5, and( beta12-beta13)-chimeras (PP1/PP2A and PP5/PP2A), provide further insight into the inhibitory actions of fostriecin family inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Targeting the PTPome in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Structural basis of protein phosphatase 1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Protein tyrosine phosphatases: from genes, to function, to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Detection of microcystins, a blue-green algal hepatotoxin, in drinking water sampled in Haimen and Fusui, endemic areas of primary liver cancer in China, by highly sensitive immunoassay

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Protein phosphatase 2A inhibitors, phoslactomycins. Effects on the cytoskeleton in NIH/3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Impact of a toxic and a non-toxic strain of Microcystis aeruginosa on the crayfish Procambarus clarkii.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Uptake and depuration of the heptapeptide toxin microcystin-LR in Mytilus galloprovincialis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Medical uses of mylabris in ancient China and recent studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

DNA-PKcs function regulated specifically by protein phosphatase 5

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Structure of the protein phosphatase 2A holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

PP2A:B56ϵ is required for Wnt/β-catenin signaling during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Primary prevention of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Hepatotoxic cyanobacteria: a review of the biological importance of microcystins in freshwater environments

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Inhibition of protein phosphatases-1 and -2A with acanthifolicin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.515564

The structure of tautomycetin, a dialkylmaleic anhydride antibiotic

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.43.890

Studies of new phosphate ester antifungal antibiotics phoslactomycins. II. Structure elucidation of phoslactomycins A to F.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.42.1026

Identifiers

DOI

10.3109/10408444.2010.515564

1 reference

24 August 2017

1 reference