(Q37843462)

24 August 2017

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title

Molecular targets of phytochemicals for cancer prevention (English)

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24 August 2017

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2

Ann M Bode

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24 August 2017

3

Zigang Dong

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24 August 2017

Ki Won Lee

1

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PubMed ID

21326325

24 August 2017

language of work or name

English

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publication date

10 February 2011

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24 August 2017

Nature Reviews Cancer

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24 August 2017

11

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24 August 2017

3

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24 August 2017

211-218

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https://scigraph.springernature.com/pub.10.1038/nrc3017

24 August 2017

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cites work

Cancer prevention research - then and now

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Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial

31 March 2020

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Molecular targets for cancer chemoprevention

31 March 2020

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Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study

31 March 2020

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Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

31 March 2020

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Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial

31 March 2020

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Evidence for a biopsy derived grade artifact among larger prostate glands

31 March 2020

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Estimating rates of true high-grade disease in the prostate cancer prevention trial

31 March 2020

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Finasteride does not increase the risk of high-grade prostate cancer: a bias-adjusted modeling approach

31 March 2020

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The influence of finasteride on the development of prostate cancer

31 March 2020

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Taxanes: an overview of the pharmacokinetics and pharmacodynamics

31 March 2020

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Resveratrol directly targets COX-2 to inhibit carcinogenesis.

31 March 2020

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The resveratrol analogue 3,5,3',4',5'-pentahydroxy-trans-stilbene inhibits cell transformation via MEK

31 March 2020

1 reference

(-)-Epigallocatechin gallate regulates CD3-mediated T cell receptor signaling in leukemia through the inhibition of ZAP-70 kinase

31 March 2020

1 reference

Fyn is a novel target of (-)-epigallocatechin gallate in the inhibition of JB6 Cl41 cell transformation

31 March 2020

1 reference

(-)-Epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78.

31 March 2020

1 reference

[6]-Gingerol suppresses colon cancer growth by targeting leukotriene A4 hydrolase

31 March 2020

1 reference

Myricetin suppresses UVB-induced skin cancer by targeting Fyn.

31 March 2020

1 reference

Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo

31 March 2020

1 reference

Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf.

31 March 2020

1 reference

The art and design of genetic screens: RNA interference.

31 March 2020

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Utilizing RNA interference to enhance cancer drug discovery

31 March 2020

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Building mammalian signalling pathways with RNAi screens

31 March 2020

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Virtual screening strategies in drug discovery

31 March 2020

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ZINC--a free database of commercially available compounds for virtual screening

31 March 2020

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The Protein Data Bank: a computer-based archival file for macromolecular structures

31 March 2020

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Advances in Homology Protein Structure Modeling

31 March 2020

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Web services at the European Bioinformatics Institute-2009

31 March 2020

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Target profiling of small molecules by chemical proteomics

31 March 2020

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Reverse-docking study of the TADDOL-catalyzed asymmetric hetero-Diels-Alder reaction

31 March 2020

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PHASE: a new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results

31 March 2020

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IKKbeta inhibitors identification part I: homology model assisted structure based virtual screening

31 March 2020

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Optimization methods for virtual screening on novel computational architectures

31 March 2020

1 reference

Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase

31 March 2020

1 reference

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.

31 March 2020

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Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine

31 March 2020

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Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1.

31 March 2020

1 reference

Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway

31 March 2020

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Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors

31 March 2020

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Chemoprevention meets glucose control

31 March 2020

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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

31 March 2020

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CDKs and cyclins in transition(s).

31 March 2020

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CDK inhibitors: positive and negative regulators of G1-phase progression

31 March 2020

1 reference

7,3',4'-Trihydroxyisoflavone inhibits epidermal growth factor-induced proliferation and transformation of JB6 P+ mouse epidermal cells by suppressing cyclin-dependent kinases and phosphatidylinositol 3-kinase

31 March 2020

1 reference

Luteolin inhibits protein kinase C(epsilon) and c-Src activities and UVB-induced skin cancer

31 March 2020

1 reference

5-deoxykaempferol plays a potential therapeutic role by targeting multiple signaling pathways in skin cancer.

31 March 2020

1 reference

Kaempferol inhibits UVB-induced COX-2 expression by suppressing Src kinase activity

31 March 2020

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Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-alpha

31 March 2020

1 reference

Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression

31 March 2020

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Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1.

31 March 2020

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MKK4 is a novel target for the inhibition of tumor necrosis factor-alpha-induced vascular endothelial growth factor expression by myricetin

31 March 2020

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Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase

31 March 2020

1 reference

A regulatory mechanism for RSK2 NH(2)-terminal kinase activity

31 March 2020

1 reference

Attenuation of proteasome-induced proteolysis in skeletal muscle by {beta}-hydroxy-{beta}-methylbutyrate in cancer-induced muscle loss

31 March 2020

1 reference

Prostaglandins and leukotrienes: advances in eicosanoid biology

31 March 2020

1 reference

Leukotrienes and lipoxins: structures, biosynthesis, and biological effects

31 March 2020

1 reference

Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions.

31 March 2020

1 reference

Altered inflammatory responses in leukotriene-deficient mice

31 March 2020

1 reference

Lipoxygenase inhibitors prevent lung carcinogenesis and inhibit non-small cell lung cancer growth

31 March 2020

1 reference

Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography †

31 March 2020

1 reference

Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells

31 March 2020

1 reference

The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy

31 March 2020

1 reference

Direct inhibition of insulin-like growth factor-I receptor kinase activity by (-)-epigallocatechin-3-gallate regulates cell transformation

31 March 2020

1 reference

Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein

31 March 2020

1 reference

Epigallocatechin gallate suppresses lung cancer cell growth through Ras-GTPase-activating protein SH3 domain-binding protein 1.

31 March 2020

1 reference

The intermediate filament protein vimentin is a new target for epigallocatechin gallate

31 March 2020

1 reference

31 March 2020

The Hallmarks of Cancer

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Principles of cancer therapy: oncogene and non-oncogene addiction

31 March 2020

1 reference

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

31 March 2020

1 reference

Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer

31 March 2020

1 reference

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

31 March 2020

1 reference

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

31 March 2020

1 reference

Molecular signatures of lung cancer--toward personalized therapy

31 March 2020

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Gene expression profiling predicts clinical outcome of breast cancer

31 March 2020

1 reference

Highlighting the science of cancer prevention

31 March 2020

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Unprecedented opportunities and promise for cancer prevention research

31 March 2020

1 reference

Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells

31 March 2020

1 reference

Structural basis for depletion of heat shock protein 90 client proteins by deguelin.

31 March 2020

1 reference

Delphinidin attenuates neoplastic transformation in JB6 Cl41 mouse epidermal cells by blocking Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling

31 March 2020

1 reference

Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin

31 March 2020

1 reference

Phosphatidylinositol 3-kinase, a novel target molecule for the inhibitory effects of kaempferol on neoplastic cell transformation

31 March 2020

1 reference

Myricetin directly targets JAK1 to inhibit cell transformation

31 March 2020

1 reference

Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase

31 March 2020

1 reference

Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin

31 March 2020

1 reference

Protective effect of quercetin against arsenite-induced COX-2 expression by targeting PI3K in rat liver epithelial cells

31 March 2020

1 reference

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

31 March 2020

1 reference

12 December 2020

Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase

1 reference

12 December 2020

Identification and characterization of molecular targets of natural products by mass spectrometry.

1 reference

12 December 2020

Chemoprevention by lipoxygenase and leukotriene pathway inhibitors of vinyl carbamate-induced lung tumors in mice

1 reference

12 December 2020

Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation

1 reference

12 December 2020

Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol.

1 reference

12 December 2020

Approaches to prevention of epithelial cancer during the preneoplastic period

1 reference

12 December 2020

The National Program for Cancer Chemotherapy

1 reference

12 December 2020

Chemoprevention of cancer

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12 December 2020

Identifiers

DOI

10.1038/NRC3017

1 reference

PubMed ID

21326325

Dimensions Publication ID

24 August 2017

0 references

1 reference

PubMed ID

21326325