(Q37852704)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

1 reference

title

IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

Agueda Gonzalez-rodriguez

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Angela M Valverde

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

publication date

14 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

Archives of Physiology and Biochemistry

25 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

105-115

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies

25 January 2020

cites work

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Cytoplasmic protein tyrosine phosphatases, regulation and function: the roles of PTP1B and TC-PTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Regulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Insulin resistance: a metabolic pathway to chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Pathogenesis of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Genetic ablation of protein tyrosine phosphatase 1B accelerates lymphomagenesis of p53-null mice through the regulation of B-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

PTP1B deficiency enhances liver growth during suckling by increasing the expression of insulin-like growth factor-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Nonalcoholic fatty liver disease: from steatosis to cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Mechanisms of hepatic fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Protein-tyrosine phosphatase 1B (PTP1B): a novel therapeutic target for type 2 diabetes mellitus, obesity and related states of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Levels of protein tyrosine phosphatase 1B determine susceptibility to apoptosis in serum-deprived hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Single nucleotide polymorphisms of protein tyrosine phosphatase 1B gene are associated with obesity in morbidly obese French subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Insulin resistance, adiponectin, cytokines in NASH: Which is the best target to treat?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Insulin/IGF-I rescues immortalized brown adipocytes from apoptosis down-regulating Bcl-xS expression, in a PI 3-kinase- and map kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Acute exercise reverses aged-induced impairments in insulin signaling in rodent skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Protein-tyrosine phosphatase 1B deficiency protects against Fas-induced hepatic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Critical nodes in signalling pathways: insights into insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Regulating insulin signaling and beta-cell function through IRS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Functional proteomic analysis of nonalcoholic fatty liver disease in rat models: enoyl-coenzyme a hydratase down-regulation exacerbates hepatic steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

Increased Expression and Activity of the Transcription Factor FOXO1 in Nonalcoholic Steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13813455.2011.557386

10.3109/13813455.2011.557386

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401320%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference