(Q37866712)

24 August 2017

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title

Targeting mitochondria as a therapeutic target in cancer (English)

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24 August 2017

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Charles E Wenner

1

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24 August 2017

1 February 2012

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Journal of Cellular Physiology

24 August 2017

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24 August 2017

227

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24 August 2017

2

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24 August 2017

450-456

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Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment

24 August 2017

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Targeting mitochondrial permeability in cancer drug development

21 January 2018

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Metabolic flexibility and cell hierarchy in metastatic cancer

21 January 2018

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mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition

21 January 2018

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Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

21 January 2018

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ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence

21 January 2018

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Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

21 January 2018

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FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor

21 January 2018

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The role of p53 in glucose metabolism

21 January 2018

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Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect

21 January 2018

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Akt stimulates aerobic glycolysis in cancer cells

21 January 2018

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Big wheel keeps on turning: apoptosome regulation and its role in chemoresistance

21 January 2018

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Targeting mitochondria for cancer therapy

21 January 2018

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Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax.

21 January 2018

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The Warburg effect and mitochondrial stability in cancer cells

21 January 2018

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Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

21 January 2018

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An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

21 January 2018

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Mnk earmarks eIF4E for cancer therapy

21 January 2018

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FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1.

21 January 2018

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Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

21 January 2018

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Tumor cell metabolism: cancer's Achilles' heel

21 January 2018

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Autophagy for the avoidance of degenerative, inflammatory, infectious, and neoplastic disease

21 January 2018

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HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells.

21 January 2018

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Mitochondrial function and energy metabolism in cancer cells: past overview and future perspectives

21 January 2018

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Hypoxia-induced autophagy: cell death or cell survival?

21 January 2018

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Encoding of Ca2+ signals by differential expression of IP3 receptor subtypes

21 January 2018

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Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF).

21 January 2018

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

21 January 2018

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Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat.

21 January 2018

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Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals

21 January 2018

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Regulation of autophagy by ROS: physiology and pathology

21 January 2018

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A functional RNAi screen identifies hexokinase 1 as a modifier of type II apoptosis

21 January 2018

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The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression

21 January 2018

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Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

21 January 2018

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HIF-1: upstream and downstream of cancer metabolism

21 January 2018

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A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

21 January 2018

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Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo

21 January 2018

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Ethanol sensitizes mitochondria to the permeability transition by inhibiting deacetylation of cyclophilin-D mediated by sirtuin-3

21 January 2018

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Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism

21 January 2018

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Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria

21 January 2018

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Resveratrol: challenges in translation to the clinic--a critical discussion.

21 January 2018

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Inositol 1,4,5-trisphosphate-induced Ca2+ signalling is involved in estradiol-induced breast cancer epithelial cell growth

21 January 2018

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HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

21 January 2018

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Small mitochondria-targeting molecules as anti-cancer agents

21 January 2018

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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

21 January 2018

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Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.22788

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24 August 2017

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PubMed ID

21503875