(Q37878206)

24 August 2017

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title

Basic mechanisms of antiepileptic drugs and their pharmacokinetic/pharmacodynamic interactions: an update (English)

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24 August 2017

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1 reference

1

Władysław Lasoń

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24 August 2017

3

Konrad Rejdak

1 reference

PubMed ID

21602586

24 August 2017

Stanisław Jerzy Czuczwar

series ordinal

4

object named as

Stanisław J Czuczwar

1 reference

24 August 2017

Monika Dudra-Jastrzębska

series ordinal

2

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24 August 2017

1 March 2011

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24 August 2017

Pharmacological Reports

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24 August 2017

63

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24 August 2017

2

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24 August 2017

271-292

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Ion channels and epilepsy

24 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Ionotropic glutamate receptor biology: effect on synaptic connectivity and function in neurological disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Lacosamide: a review of preclinical properties.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII)

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: an isobolographic analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Felbamate: a new antiepileptic drug

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Effect of caffeine on the anticonvulsant effects of oxcarbazepine, lamotrigine and tiagabine in a mouse model of generalized tonic-clonic seizures

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Calcium currents in rat thalamocortical relay neurones: kinetic properties of the transient, low-threshold current.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Mechanisms of action of antiepileptic drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Pharmacodynamic interactions between antiepileptic drugs: preclinical data based on isobolography

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

The new generation of GABA enhancers. Potential in the treatment of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Polytherapy in epilepsy: the experimental evidence

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Retigabine: the newer potential antiepileptic drug.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Mechanisms of action of antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewed

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Influence of retigabine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

AMPA receptor antagonists as potential anticonvulsant drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

1 reference

7 January 2021

New antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Molecular composition of GABAC receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Induction of ethinylestradiol and levonorgestrel metabolism by oxcarbazepine in healthy women

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Vigabatrin in the treatment of infantile spasms in tuberous sclerosis: literature review

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

1 reference

7 January 2021

Phase 2 trial of talampanel, a glutamate receptor inhibitor, for adults with recurrent malignant gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Future directions for epilepsy research

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Effect of two noncompetitive AMPA receptor antagonists GYKI 52466 and GYKI 53405 on vigilance, behavior and spike-wave discharges in a genetic rat model of absence epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

NMDA receptors in clinical neurology: excitatory times ahead

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Roles of group II metabotropic glutamate receptors in modulation of seizure activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Effects of tiagabine and vigabatrin on GABA uptake into primary cultures of rat cortical astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Lamotrigine inhibits postsynaptic AMPA receptor and glutamate release in the dentate gyrus

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Zonisamide: chemistry, mechanism of action, and pharmacokinetics.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Ion channel defects in idiopathic epilepsies

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Drug glucuronidation in clinical psychopharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Functional, metabolic, and synaptic changes after seizures as potential targets for antiepileptic therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Isobolographic analysis of interaction between drugs with nonparallel dose-response relationship curves: a practical application.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Preclinical profile of combinations of some second-generation antiepileptic drugs: an isobolographic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Synergistic interaction of gabapentin with tiagabine in the hot-plate test in mice: an isobolographic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Pharmacological and behavioral characteristics of interactions between vigabatrin and conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

1 reference

7 January 2021

The dual roles of GABA in seizures and epilepsy generate more excitement

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Efficacy and adverse effects of established and new antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Molecular targets for antiepileptic drug development

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: I. Anticonvulsant profile in mice and rats

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Glutamate metabotropic receptors as targets for drug therapy in epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Effects of retigabine on the neurodegeneration and extracellular glutamate changes induced by 4-aminopyridine in rat hippocampus in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Emerging drugs for partial onset seizures.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Induction of CYP1A2 activity by carbamazepine in children using the caffeine breath test

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Felbamate: consensus of current clinical experience

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Aplastic anemia in a patient receiving felbamate for complex partial seizures

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Clinical pharmacology and therapeutic use of the new antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

EXPERIMENTAL DETERMINATION OF THE ANTICONVULSANT PROPERTIES OF SOME PHENYL DERIVATIVES

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Clinical pharmacokinetic interactions between antiepileptic drugs and hormonal contraceptives

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Comparison of oxcarbazepine and carbamazepine: a double-blind study

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Acetazolamide in the treatment of seizures

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Benzodiazepines in epilepsy: pharmacology and pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Diverse mechanisms of antiepileptic drugs in the development pipeline

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Newer anticonvulsants: comparative review of drug interactions and adverse effects.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Zonisamide enhances slow sodium inactivation in Myxicola

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Zonisamide in the treatment of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Topiramate: preclinical evaluation of structurally novel anticonvulsant.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

The mechanisms of action of gabapentin and pregabalin

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Chromosomal abnormalities and epilepsy: a review for clinicians and gene hunters

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Mechanisms of action of antiepileptic drugs: the search for synergy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Seizure freedom with more than one antiepileptic drug

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Interactions between drugs and occupied receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

A summary of mechanistic hypotheses of gabapentin pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-ray crystallographic studies

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Anticonvulsant sulfonamides/sulfamates/sulfamides with carbonic anhydrase inhibitory activity: drug design and mechanism of action

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Drug selection for the newly diagnosed patient: when is a new generation antiepileptic drug indicated?

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Basis of the antiseizure action of phenytoin

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

New anti-epileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Topiramate: a potent anticonvulsant in the amygdala-kindled rat

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Mechanisms of Action of Antiepileptic Drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Potassium channels as anti-epileptic drug targets

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Voltage-gated potassium channels as therapeutic targets

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Novel anticonvulsant drugs targeting voltage-dependent ion channels

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

Influence of single and repeated doses of oxcarbazepine on the pharmacokinetic profile of felodipine

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970497-2

7 January 2021

10.1016/S1734-1140(11)70497-2

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21602586