(Q37962336)

26 August 2017

title

HDAC inhibitors in parasitic diseases (English)

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26 August 2017

1

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26 August 2017

3

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26 August 2017

Ashraful Haque

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publication date

29 November 2011

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Immunology & Cell Biology

26 August 2017

published in

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26 August 2017

volume

90

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26 August 2017

issue

1

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26 August 2017

page(s)

66-77

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Artemisinin Resistance in Plasmodium falciparum Malaria

26 August 2017

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The genome of the kinetoplastid parasite, Leishmania major

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Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation

21 January 2018

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A Leishmania major protein with extensive homology to silent information regulator 2 of Saccharomyces cerevisiae

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Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death.

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The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD+ -dependent deacetylase and ADP-ribosyltransferase

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Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation.

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The contribution of Toll-like receptor 2 to the innate recognition of a Leishmania infantum silent information regulator 2 protein.

21 January 2018

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Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum

21 January 2018

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Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum

21 January 2018

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Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

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Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 2.

21 January 2018

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Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.

21 January 2018

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Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

21 January 2018

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Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

21 January 2018

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Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro

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Heat shock protein 90 as a drug target against protozoan infections: biochemical characterization of HSP90 from Plasmodium falciparum and Trypanosoma evansi and evaluation of its inhibitor as a candidate drug

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21 January 2018

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21 January 2018

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A series of potent and selective, triazolylphenyl-based histone deacetylases inhibitors with activity against pancreatic cancer cells and Plasmodium falciparum

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Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components

21 January 2018

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Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage.

21 January 2018

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Histone acetylation and methylation at sites initiating divergent polycistronic transcription in Trypanosoma cruzi

21 January 2018

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Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton

21 January 2018

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In vitro antimalarial activity of hyperforin, a prenylated acylphloroglucinol. A structure-activity study

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity

21 January 2018

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A survey of synthetic and natural phytotoxic compounds and phytoalexins as potential antimalarial compounds.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Stage-specific antileishmanial activity of an inhibitor of SIR2 histone deacetylase.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

In vitro antileishmanial activity of nicotinamide.

21 January 2018

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Bisnaphthalimidopropyl derivatives as inhibitors of Leishmania SIR2 related protein 1.

21 January 2018

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The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site

21 January 2018

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Isoform-selective histone deacetylase inhibitors

21 January 2018

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Resistance to antimalarial compounds: methods and applications

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Defining the role of gene regulation in resistance to HDAC inhibitors--mechanisms beyond P-glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Depsipeptide-resistant KU812 cells show reversible P-glycoprotein expression, hyper-acetylated histones, and modulated gene expression profile

21 January 2018

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Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes

21 January 2018

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21 January 2018

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21 January 2018

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Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection

21 January 2018

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The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice

21 January 2018

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Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

21 January 2018

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Adjunctive therapy for cerebral malaria and other severe forms of Plasmodium falciparum malaria

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

21 January 2018

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21 January 2018

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Implementation of human schistosomiasis control: Challenges and prospects

21 January 2018

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Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

A proteomic view of the Plasmodium falciparum life cycle

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

A protein interaction network of the malaria parasite Plasmodium falciparum

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

ToxoDB: accessing the Toxoplasma gondii genome

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Leishmania major: cell type dependent distribution of a 43 kDa antigen related to silent information regulatory-2 protein family.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

SchistoDB: a Schistosoma mansoni genome resource

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Histone deacetylase inhibitors: overview and perspectives

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Histone deacetylase inhibitors in cancer therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

Antimalarial and antileishmanial activities of aroyl-pyrrolyl-hydroxyamides, a new class of histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.97

Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin

21 January 2018

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Proof of interaction between Leishmania SIR2RP1 deacetylase and chaperone HSP83

21 January 2018

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Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies

21 January 2018

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Loss of stages after continuous passage of Toxoplasma gondii and Besnoitia jellisoni

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2011.97

7 January 2021

Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.97

7 January 2021

Synthesis of apicidin-derived quinolone derivatives: parasite-selective histone deacetylase inhibitors and antiproliferative agents

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.97

7 January 2021

A novel ISWI is involved in VSG expression site downregulation in African trypanosomes

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.97

7 January 2021

Comparative protein modeling and surface analysis of Leishmania sirtuin: A potential target for antileishmanial drug discovery

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.97

7 January 2021

Cutaneous leishmaniasis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.97

7 January 2021

Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.97

7 January 2021

Identifiers

DOI

10.1038/ICB.2011.97

1 reference

26 August 2017

1 reference