(Q37990683)

26 August 2017

title

Mammalian homologues of Drosophila fused kinase (English)

1 reference

26 August 2017

Mammalian Homologues of Drosophila Fused Kinase (English)

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

26 December 2024

0 references

Alla Maloverjan

1

1 reference

26 August 2017

Marko Piirsoo

2

1 reference

26 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22391301

26 December 2024

publication date

1 January 2012

1 reference

26 August 2017

2012

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22391301

full work available at URL

26 December 2024

https://api.elsevier.com/content/article/PII:B9780123946225000055?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

https://api.elsevier.com/content/article/PII:B9780123946225000055?httpAccept=text/plain

26 December 2024

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

26 December 2024

published in

Vitamins and Hormones

1 reference

26 August 2017

volume

88

1 reference

26 August 2017

page(s)

91-113

1 reference

Molecular characterization of Pegarn: a Drosophila homolog of UNC-51 kinase

26 August 2017

cites work

1

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Modulation of Hedgehog target gene expression by the Fused serine-threonine kinase in wing imaginal discs.

26 December 2024

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An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling

26 December 2024

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Evolutionary developmental biology and genomics

26 December 2024

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Evolution of Atg1 function and regulation

26 December 2024

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Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism

26 December 2024

9

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Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus

26 December 2024

10

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Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development

26 December 2024

11

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Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

26 December 2024

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Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.

26 December 2024

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Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules

26 December 2024

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Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused

26 December 2024

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Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

26 December 2024

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Expression of the human FUSED protein in Drosophila

26 December 2024

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Essential role of stromally induced hedgehog signaling in B-cell malignancies

26 December 2024

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Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

26 December 2024

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Mapping the phosphorylation sites of Ulk1.

26 December 2024

21

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A model for anteroposterior patterning of the vertebrate limb based on sequential long- and short-range Shh signalling and Bmp signalling

26 December 2024

22

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Characterization of the physical interaction of Gli proteins with SUFU proteins

26 December 2024

23

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Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs

26 December 2024

24

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Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus

26 December 2024

25

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The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development

26 December 2024

26

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction

26 December 2024

27

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells

26 December 2024

28

1 reference

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Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

26 December 2024

29

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Evidence for the Involvement of theGliGene Family in Embryonic Mouse Lung Development

26 December 2024

30

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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

26 December 2024

31

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Cilia and Hedgehog responsiveness in the mouse

26 December 2024

32

1 reference

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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

26 December 2024

33

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter

26 December 2024

34

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Sonic hedgehog induces the segregation of patched and smoothened in endosomes

26 December 2024

35

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus

26 December 2024

36

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail

26 December 2024

37

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia

26 December 2024

38

1 reference

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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

26 December 2024

39

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Fused kinase is stabilized by Cdc37/Hsp90 and enhances Gli protein levels

26 December 2024

40

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy

26 December 2024

41

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development

26 December 2024

42

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Genetic dissection of the Drosophila Cubitus interruptus signaling complex

26 December 2024

43

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2

26 December 2024

44

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathway

26 December 2024

45

1 reference

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Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway

26 December 2024

46

1 reference

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A possible role of mouse Fused (STK36) in Hedgehog signaling and Gli transcription factor regulation

26 December 2024

47

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

The last 59 amino acids of Smoothened cytoplasmic tail directly bind the protein kinase Fused and negatively regulate the Hedgehog pathway.

26 December 2024

48

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1

26 December 2024

49

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development

26 December 2024

50

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus

26 December 2024

51

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium

26 December 2024

53

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Suppressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway

26 December 2024

54

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Hedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the kinesin-related protein Costal2.

26 December 2024

55

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus

26 December 2024

56

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Gli regulation by the opposing activities of fused and suppressor of fused

26 December 2024

57

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Autophagy facilitates oncogene-induced senescence

26 December 2024

58

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused

26 December 2024

59

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

26 December 2024

60

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator

26 December 2024

61

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

The FU gene and its possible protein isoforms

26 December 2024

62

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila

26 December 2024

64

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.

26 December 2024

66

1 reference

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Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling

26 December 2024

67

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Protein kinase C-delta and mitogen-activated protein/extracellular signal-regulated kinase-1 control GLI activation in hedgehog signaling

26 December 2024

68

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

26 December 2024

69

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Hedgehog Elicits Signal Transduction by Means of a Large Complex Containing the Kinesin-Related Protein Costal2

26 December 2024

70

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog

26 December 2024

71

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling

26 December 2024

72

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog

26 December 2024

73

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Expression of hedgehog proteins in the human thymus

26 December 2024

74

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal

26 December 2024

76

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Costal2, a Novel Kinesin-Related Protein in the Hedgehog Signaling Pathway

26 December 2024

77

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Regulation of Ci-SCFSlimb binding, Ci proteolysis, and hedgehog pathway activity by Ci phosphorylation.

26 December 2024

78

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

26 December 2024

79

1 reference

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Identification of a tetrameric hedgehog signaling complex

26 December 2024

80

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

26 December 2024

81

1 reference

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Patched acts catalytically to suppress the activity of Smoothened

26 December 2024

82

1 reference

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Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

26 December 2024

83

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Molecular organisation and expression pattern of the segment polarity gene fused of Drosophila melanogaster.

26 December 2024

84

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Phosphorylation of the fused protein kinase in response to signaling from hedgehog

26 December 2024

85

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A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons

26 December 2024

87

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https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Role of Unc51.1 and its binding partners in CNS axon outgrowth

26 December 2024

88

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Sonic hedgehog pathway genes are expressed and transcribed in the adult mouse epididymis

26 December 2024

89

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling

26 December 2024

90

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus

26 December 2024

92

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

26 December 2024

93

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus

26 December 2024

94

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

26 December 2024

95

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis

26 December 2024

96

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo

26 December 2024

97

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains

26 December 2024

98

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https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Autophagy mediates the mitotic senescence transition

26 December 2024

99

1 reference

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Extensive phosphorylation of Smoothened in Hedgehog pathway activation

26 December 2024

100

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus.

26 December 2024

101

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A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

26 December 2024

102

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Hedgehog regulates smoothened activity by inducing a conformational switch

26 December 2024

103

1 reference

https://api.crossref.org/works/10.1016/B978-0-12-394622-5.00005-5

Hedgehog Activates Fused through Phosphorylation to Elicit a Full Spectrum of Pathway Responses

26 December 2024

104

1 reference

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26 December 2024

Identifiers

1 reference

26 August 2017

1 reference