(Q46976403)

27 December 2017

title

Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus (English)

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27 December 2017

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6

Iannis Aifantis

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27 December 2017

author name string

Abdeljabar El Andaloussi

1

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27 December 2017

Stephanie Graves

2

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27 December 2017

Fanyong Meng

3

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27 December 2017

Malay Mandal

4

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27 December 2017

Mona Mashayekhi

5

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27 December 2017

language of work or name

English

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publication date

5 March 2006

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27 December 2017

published in

Nature Immunology

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27 December 2017

volume

7

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issue

4

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27 December 2017

page(s)

418-426

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27 December 2017

The impact of pre-T-cell receptor signals on gene expression in developing T cells

cites work

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Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor beta locus.

21 January 2018

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On the role of the pre-T cell receptor in alphabeta versus gammadelta T lineage commitment

21 January 2018

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Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

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Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

21 January 2018

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Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

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Wnt signaling in the thymus

21 January 2018

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Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

21 January 2018

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The origin of pattern and polarity in the Drosophila embryo

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Signal integration during development: insights from the Drosophila eye.

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Mutations affecting segment number and polarity in Drosophila

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The world according to hedgehog

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More surprises in the Hedgehog signaling pathway

21 January 2018

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Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte

21 January 2018

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Reduced thymocyte development in sonic hedgehog knockout embryos

21 January 2018

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Expression of hedgehog proteins in the human thymus

21 January 2018

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Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node

21 January 2018

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T-cell development made simple

21 January 2018

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

21 January 2018

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 January 2018

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Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

21 January 2018

1 reference

A mouse model for medulloblastoma and basal cell nevus syndrome

21 January 2018

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Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

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Gli and hedgehog in cancer: tumours, embryos and stem cells.

21 January 2018

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Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

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BMP signaling is required for normal thymus development.

21 January 2018

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Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos

21 January 2018

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Sonic hedgehog promotes cell cycle progression in activated peripheral CD4(+) T lymphocytes

21 January 2018

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Sonic hedgehog is produced by follicular dendritic cells and protects germinal center B cells from apoptosis.

21 January 2018

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Hedgehog signaling and human disease

21 January 2018

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RAG-1-deficient mice have no mature B and T lymphocytes

21 January 2018

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Circulating hematopoietic progenitors with T lineage potential

21 January 2018

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7 January 2021

Notch and the immune system

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7 January 2021

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

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7 January 2021

Sonic hedgehog regulates early human thymocyte differentiation by counteracting the IL-7-induced development of CD34+ precursor cells

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7 January 2021

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain

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7 January 2021

Sonic Hedgehog Signaling Modulates Activation of and Cytokine Production by Human Peripheral CD4+ T Cells

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7 January 2021

Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT

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7 January 2021

A critical role for the cytoplasmic tail of pTα in T lymphocyte development

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7 January 2021

Identifiers

DOI

10.1038/NI1313

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27 December 2017

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27 December 2017