(Q37997076)

26 August 2017

title

The role of Tec family kinases in the regulation of T-helper-cell differentiation (English)

1 reference

26 August 2017

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2

Wilfried Ellmeier

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26 August 2017

Nicole Boucheron

1

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language of work or name

1 reference

1 April 2012

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International Reviews of Immunology

26 August 2017

published in

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26 August 2017

volume

31

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26 August 2017

issue

2

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26 August 2017

page(s)

133-154

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Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells

26 August 2017

cites work

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Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk

21 January 2018

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TXK, a novel human tyrosine kinase expressed in T cells shares sequence identity with Tec family kinases and maps to 4p12

21 January 2018

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Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage

21 January 2018

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Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

21 January 2018

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Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

21 January 2018

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Novel t(5;9)(q33;q22) fuses ITK to SYK in unspecified peripheral T-cell lymphoma

21 January 2018

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The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma

21 January 2018

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Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec family kinases in T lymphocyte development and function

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Interaction of SLP adaptors with the SH2 domain of Tec family kinases

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Regulatory intramolecular association in a tyrosine kinase of the Tec family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Phylogeny of Tec family kinases identification of a premetazoan origin of Btk, Bmx, Itk, Tec, Txk, and the Btk regulator SH3BP5.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The role of Tec family kinases in mononuclear phagocytes

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Txk, a nonreceptor tyrosine kinase of the Tec family, is expressed in T helper type 1 cells and regulates interferon gamma production in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

c-Maf regulates IL-10 expression during Th17 polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec family kinases modulate thresholds for thymocyte development and selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

ITK and IL-15 support two distinct subsets of CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Naive and innate memory phenotype CD4+ T cells have different requirements for active Itk for their development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Homeostasis of memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

MHC class Ib molecules bridge innate and acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

21 January 2018

The biology of NKT cells

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Raising the NKT cell family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Development and selection of gammadelta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

A key role for Itk in both IFN gamma and IL-4 production by NKT cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Attenuation of Immunological Symptoms of Allergic Asthma in Mice Lacking the Tyrosine Kinase ITK

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The transcription factor PLZF directs the effector program of the NKT cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

SAP Protein-Dependent Natural Killer T-like Cells Regulate the Development of CD8+ T Cells with Innate Lymphocyte Characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Impaired T-cell development in the absence of Vav1 and Itk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec family kinases in lymphocyte signaling and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Adapters in lymphocyte signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

ZAP-70: an essential kinase in T-cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

In vivo significance of ITK-SLP-76 interaction in cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

T-cell signaling regulated by the Tec family kinase, Itk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Differential roles of Lck and Itk in T cell response to antigen recognition revealed by calcium imaging and electron microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Inducible T cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the T cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec kinases, actin, and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Requirement for Tec kinases in chemokine-induced migration and activation of Cdc42 and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Defective Fas ligand expression and activation-induced cell death in the absence of IL-2-inducible T cell kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The role of Tec protein-tyrosine kinase in T cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec regulates platelet activation by GPVI in the absence of Btk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Nucleocytoplasmic shuttling of Bruton's tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

How are T(H)1 and T(H)2 effector cells made?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

How are T(H)2-type immune responses initiated and amplified?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Control of regulatory T cell lineage commitment and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Mechanisms of foxp3+ T regulatory cell-mediated suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Regulatory T cells: history and perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Regulatory T cells and infection: a dangerous necessity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Regulation and pro-inflammatory function of interleukin-17 family cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Differentiation and function of Th17 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Transcriptional regulation of Th17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The biological functions of T helper 17 cell effector cytokines in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

IL-17/Th17 in anti-fungal immunity: what's new?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Cytokines that regulate autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Asthma: mechanisms of disease persistence and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Importance of cytokines in murine allergic airway disease and human asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Heterogeneity and plasticity of T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Effector T cell plasticity: flexibility in the face of changing circumstances

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The functional plasticity of T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

T helper cell populations: as flexible as the skin?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

From interleukin-9 to T helper 9 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The Family of IL-10-secreting CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Type 1 regulatory T cells (Tr1) in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Follicular helper T cells: lineage and location

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Follicular helper CD4 T cells (TFH)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Plasticity of CD4+ T cell lineage differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Genetic proof for the transient nature of the Th17 phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Evidence of autophosphorylation in Txk: Y91 is an autophosphorylation site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Skewed Th1 responses caused by excessive expression of Txk, a member of the Tec family of tyrosine kinases, in patients with Behcet's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Excessive expression of Txk, a member of the Tec family of tyrosine kinases, contributes to excessive Th1 cytokine production by T lymphocytes in patients with Behcet's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Role of Txk, a member of the Tec family of tyrosine kinases, in immune-inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

TEC-family kinases: regulators of T-helper-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Th1-dominant shift of T cell cytokine production, and subsequent reduction of serum immunoglobulin E response by administration in vivo of plasmid expressing Txk/Rlk, a member of Tec family tyrosine kinases, in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

The role of Tec family kinases in myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

ITK inhibitors in inflammation and immune-mediated disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Selective Itk inhibitors block T-cell activation and murine lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

5-Aminomethylbenzimidazoles as potent ITK antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Identification of Itk/Tsk Src homology 3 domain ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Resting lymphocyte kinase (Rlk/Txk) phosphorylates the YVKM motif and regulates PI 3-kinase binding to T-cell antigen CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Structural characterization of a proline-driven conformational switch within the Itk SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec kinases: modulators of lymphocyte signaling and development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

TCR/CD3-Induced activation and binding of Emt/Itk to linker of activated T cell complexes: requirement for the Src homology 2 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

PKCtheta and Itk functionally interact during primary mouse CD3+ T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

A remote substrate docking mechanism for the tec family tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Characterization of a novel interaction between transcription factor TFII-I and the inducible tyrosine kinase in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Phosphorylation of the linker for activation of T-cells by Itk promotes recruitment of Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

Biochemical and genetic analyses of the Tec kinases Itk and Rlk/Txk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.664798

10.3109/08830185.2012.664798

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference