(Q38029555)

27 August 2017

Insights into cancer metastasis from a clinicopathologic perspective: Epithelial-Mesenchymal Transition is not a necessary step (English)

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27 August 2017

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Michael Herman Chui

1

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PubMed ID

22833228

27 August 2017

language of work or name

English

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publication date

28 September 2012

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International Journal of Cancer

27 August 2017

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27 August 2017

132

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27 August 2017

7

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27 August 2017

1487-1495

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The fallacy of epithelial mesenchymal transition in neoplasia

27 August 2017

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The basics of epithelial-mesenchymal transition

21 January 2018

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The ins and outs of the epithelial to mesenchymal transition in health and disease

21 January 2018

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Distinct tyrosine autophosphorylation sites mediate induction of epithelial mesenchymal like transition by an activated ErbB-2/Neu receptor.

21 January 2018

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TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

21 January 2018

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A positive role of cadherin in Wnt/β-catenin signalling during epithelial-mesenchymal transition

21 January 2018

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NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

21 January 2018

1 reference

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

21 January 2018

1 reference

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

Inappropriate gene expression in human cancer and its far-reaching biological and clinical significance

21 January 2018

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Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

21 January 2018

1 reference

Evidence for mesenchymal-epithelial transition associated with mouse hepatic stem cell differentiation

21 January 2018

1 reference

Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?

21 January 2018

1 reference

Molecular definition of breast tumor heterogeneity

21 January 2018

1 reference

Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

21 January 2018

1 reference

Apoptosis and genomic instability

21 January 2018

1 reference

Mutations of mitotic checkpoint genes in human cancers

21 January 2018

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The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability

21 January 2018

1 reference

Genetic instabilities in human cancers

21 January 2018

1 reference

Accumulation of driver and passenger mutations during tumor progression

21 January 2018

1 reference

Making sense of cancer genomic data

21 January 2018

1 reference

Expression of melanocyte-related genes in human breast cancer and its implications

21 January 2018

1 reference

Human breast cancer cell lines co-express neuronal, epithelial, and melanocytic differentiation markers in vitro and in vivo

21 January 2018

1 reference

Tumour metastasis: is tissue an issue?

21 January 2018

1 reference

Collective cell migration in morphogenesis, regeneration and cancer

21 January 2018

1 reference

The colony forming efficiency of single cells and cell aggregates from a spontaneous mouse mammary tumour using the lung colony assay

21 January 2018

1 reference

An invasion-independent pathway of blood-borne metastasis: a new murine mammary tumor model

21 January 2018

1 reference

Morphological evidence for an invasion-independent metastasis pathway exists in multiple human cancers

21 January 2018

1 reference

Micronodular transformation as a novel mechanism of VEGF-A-induced metastasis

21 January 2018

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Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype

21 January 2018

1 reference

Risk of Mortality by Histologic Type of Breast Cancer Among Women Aged 50 to 79 Years

21 January 2018

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Circulating tumour tissue fragments in patients with pulmonary metastasis of clear cell renal cell carcinoma

21 January 2018

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Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

21 January 2018

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Relevance of disseminated tumour cells in blood and bone marrow of patients with solid epithelial tumours in perspective

21 January 2018

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Visualization of early events in tumor formation of eGFP-transfected rat colon cancer cells in liver

21 January 2018

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Heterogeneity in cancer: cancer stem cells versus clonal evolution

21 January 2018

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The clonal evolution of tumor cell populations

21 January 2018

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Clonal expansion of p53 mutant cells is associated with brain tumour progression

21 January 2018

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Distant metastasis occurs late during the genetic evolution of pancreatic cancer

21 January 2018

1 reference

Analysis of colorectal tumor progression by microdissection and comparative genomic hybridization

21 January 2018

1 reference

Genome remodelling in a basal-like breast cancer metastasis and xenograft

21 January 2018

1 reference

MYC gene amplification is often acquired in lethal distant breast cancer metastases of unamplified primary tumors

21 January 2018

1 reference

Cancer stem cells in solid tumors: an overview

21 January 2018

1 reference

Recent advances in cancer stem cells

21 January 2018

1 reference

Modeling the initiation and progression of human acute leukemia in mice

21 January 2018

1 reference

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

21 January 2018

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myc maintains embryonic stem cell pluripotency and self-renewal

21 January 2018

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Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion

21 January 2018

1 reference

Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation

21 January 2018

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CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells

21 January 2018

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Myc represses primitive endoderm differentiation in pluripotent stem cells.

21 January 2018

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An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

21 January 2018

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Efficient tumour formation by single human melanoma cells

21 January 2018

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Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content

21 January 2018

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Isolation of stem/progenitor cells from normal lung tissue of adult humans.

21 January 2018

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Wnt signaling regulates Snai1 expression and cellular localization in the mouse intestinal epithelial stem cell niche.

21 January 2018

1 reference

Snail2, a mediator of epithelial-mesenchymal transitions, expressed in progenitor cells of the developing endocrine pancreas

21 January 2018

1 reference

The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer

21 January 2018

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Roles of TGF-beta family signaling in stem cell renewal and differentiation

21 January 2018

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Feeder layer- and serum-free culture of human embryonic stem cells

21 January 2018

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TGFbeta and Wnt pathway cross-talk

21 January 2018

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Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling

21 January 2018

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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

21 January 2018

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Molecular portraits of human breast tumours

21 January 2018

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Gene expression profiling identifies molecular subtypes of inflammatory breast cancer

21 January 2018

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21 January 2018

Fibroblasts in cancer

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Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

21 January 2018

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Role of tissue stroma in cancer cell invasion

21 January 2018

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ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients

21 January 2018

1 reference

Highly methylated genes in colorectal neoplasia: implications for screening

21 January 2018

1 reference

Molecular markers and clinical behavior of uterine carcinosarcomas: focus on the epithelial tumor component

21 January 2018

1 reference

Molecular pathogenesis of pulmonary carcinosarcoma as determined by microdissection-based allelotyping.

21 January 2018

1 reference

Histologic evaluation of metastases in renal cell carcinoma with sarcomatoid transformation and its implications for systemic therapy

21 January 2018

1 reference

Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues

21 January 2018

1 reference

Curing metastatic cancer: lessons from testicular germ-cell tumours

21 January 2018

1 reference

International Germ Cell Consensus Classification: a prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group

21 January 2018

1 reference

Pathological definition and clinical significance of vascular invasion in thyroid carcinomas of follicular epithelial derivation

21 January 2018

1 reference

Clinical Significance and Molecular Characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in Patients With Small-Cell Lung Cancer

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.27745

1 reference

27 August 2017

1 reference

PubMed ID

22833228