(Q38081956)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414361%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

New targets for glycosaminoglycans and glycosaminoglycans as novel targets (English)

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24 February 2020

1

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24 February 2020

author name string

Martina Theuer

2

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24 February 2020

Daniela Schweiger

3

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24 February 2020

Tiziana Adage

4

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24 February 2020

Andreas J Kungl

5

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24 February 2020

publication date

1 February 2013

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Expert Review of Proteomics

24 February 2020

published in

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24 February 2020

volume

10

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24 February 2020

issue

1

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24 February 2020

page(s)

77-95

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The structure of glycosaminoglycans and their interactions with proteins.

24 February 2020

cites work

1 reference

Proteoglycanomics: tools to unravel the biological function of glycosaminoglycans.

21 January 2018

1 reference

21 January 2018

Proteoglycan sequence

1 reference

Heparin-protein interactions

21 January 2018

1 reference

Role of glycosaminoglycans in cellular communication.

21 January 2018

1 reference

Heparan sulphate proteoglycans: the sweet side of development

21 January 2018

1 reference

Transmembrane signaling proteoglycans

21 January 2018

1 reference

Glycosaminoglycans as regulators of stem cell differentiation.

21 January 2018

1 reference

Glycosaminoglycans: key players in cancer cell biology and treatment

21 January 2018

1 reference

21 January 2018

Sugar codes for axons?

1 reference

The anticoagulant activation of antithrombin by heparin

21 January 2018

1 reference

The anticoagulant and antithrombotic mechanisms of heparin

21 January 2018

1 reference

Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation

21 January 2018

1 reference

The role of heparan sulphate in inflammation

21 January 2018

1 reference

Therapeutic value of glycosaminoglycans in cancer

21 January 2018

1 reference

The sweet and sour of cancer: glycans as novel therapeutic targets

21 January 2018

1 reference

Heparan sulfate as a therapeutic target in amyloidogenesis: prospects and possible complications

21 January 2018

1 reference

Glycosaminoglycans, protein aggregation and neurodegeneration

21 January 2018

1 reference

Diverse functions of glycosaminoglycans in infectious diseases.

21 January 2018

1 reference

Insight into a conserved lifestyle: protein-carbohydrate adhesion strategies of vector-borne pathogens.

21 January 2018

1 reference

Therapeutically targeting protein-glycan interactions

21 January 2018

1 reference

Sulfated oligosaccharides: new targets for drug development?

21 January 2018

1 reference

A systems biology approach for the investigation of the heparin/heparan sulfate interactome

21 January 2018

1 reference

Enzymatic degradation of glycosaminoglycans

21 January 2018

1 reference

Formation of anhydrosugars in the chemical depolymerization of heparin

21 January 2018

1 reference

Disaccharide compositional analysis of heparan sulfate and heparin polysaccharides using UV or high-sensitivity fluorescence (BODIPY) detection.

21 January 2018

1 reference

Separation of a complex mixture of heparin-derived oligosaccharides using reversed-phase high-performance liquid chromatography

21 January 2018

1 reference

Quantification of heparan sulfate disaccharides using ion-pairing reversed-phase microflow high-performance liquid chromatography with electrospray ionization trap mass spectrometry.

21 January 2018

1 reference

Comparative glycomics of connective tissue glycosaminoglycans

21 January 2018

1 reference

A chip-based amide-HILIC LC/MS platform for glycosaminoglycan glycomics profiling

21 January 2018

1 reference

Chip electrospray mass spectrometry for carbohydrate analysis

21 January 2018

1 reference

Nanoliquid chromatography-mass spectrometry of oligosaccharides employing graphitized carbon chromatography on microchip with a high-accuracy mass analyzer.

21 January 2018

1 reference

Mass spectrometric method for determining the uronic acid epimerization in heparan sulfate disaccharides generated using nitrous acid

21 January 2018

1 reference

Capillary electrophoresis of complex natural polysaccharides

21 January 2018

1 reference

Capillary electrophoretic separation of heparin oligosaccharides under conditions amenable to mass spectrometric detection

21 January 2018

1 reference

Determination of twelve heparin- and heparan sulfate-derived disaccharides as 2-aminoacridone derivatives by capillary zone electrophoresis using ultraviolet and laser-induced fluorescence detection.

21 January 2018

1 reference

Electrophoretic approaches to the analysis of complex polysaccharides.

21 January 2018

1 reference

Fluorophore-assisted carbohydrate electrophoresis (FACE) of glycosaminoglycans

21 January 2018

1 reference

Tandem mass spectrometry of sulfated heparin-like glycosaminoglycan oligosaccharides

21 January 2018

1 reference

Analysis of Glycosaminoglycans Using Mass Spectrometry

21 January 2018

1 reference

Modern developments in mass spectrometry of chondroitin and dermatan sulfate glycosaminoglycans

21 January 2018

1 reference

Mass spectrometry of oligosaccharides.

21 January 2018

1 reference

Utility of non-covalent complexes in the matrix-assisted laser desorption ionization mass spectrometry of heparin-derived oligosaccharides

21 January 2018

1 reference

Matrix-assisted laser desorption/ionization mass spectrometric analysis of uncomplexed highly sulfated oligosaccharides using ionic liquid matrices

21 January 2018

1 reference

Towards GAG glycomics: analysis of highly sulfated heparins by MALDI-TOF mass spectrometry

21 January 2018

1 reference

Complete mass spectral characterization of a synthetic ultralow-molecular-weight heparin using collision-induced dissociation

21 January 2018

1 reference

Electron detachment dissociation of glycosaminoglycan tetrasaccharides

21 January 2018

1 reference

Distinguishing glucuronic from iduronic acid in glycosaminoglycan tetrasaccharides by using electron detachment dissociation.

21 January 2018

1 reference

Negative electron transfer dissociation of glycosaminoglycans.

21 January 2018

1 reference

Tandem mass spectrometry of heparan sulfate negative ions: sulfate loss patterns and chemical modification methods for improvement of product ion profiles

21 January 2018

1 reference

The proteoglycan bikunin has a defined sequence

21 January 2018

1 reference

Recent advances in the analysis of carbohydrates for biomedical use.

21 January 2018

1 reference

Heparin sequencing using enzymatic digestion and ESI-MSn with HOST: a heparin/HS oligosaccharide sequencing tool

21 January 2018

1 reference

Software tool for the structural determination of glycosaminoglycans by mass spectrometry.

21 January 2018

1 reference

Exposure to common food additive carrageenan leads to reduced sulfatase activity and increase in sulfated glycosaminoglycans in human epithelial cells

21 January 2018

1 reference

A comprehensive compositional analysis of heparin/heparan sulfate-derived disaccharides from human serum

21 January 2018

1 reference

Validation of disaccharide compositions derived from dermatan sulfate and heparan sulfate in mucopolysaccharidoses and mucolipidoses II and III by tandem mass spectrometry.

21 January 2018

1 reference

A structural analysis of glycosaminoglycans from lethal and nonlethal breast cancer tissues: toward a novel class of theragnostics for personalized medicine in oncology?

21 January 2018

1 reference

Analysis of oversulfation in biglycan chondroitin/dermatan sulfate oligosaccharides by chip-based nanoelectrospray ionization multistage mass spectrometry.

21 January 2018

1 reference

Human follicular fluid heparan sulfate contains abundant 3-O-sulfated chains with anticoagulant activity

21 January 2018

1 reference

Effects on molecular conformation and anticoagulant activities of 1,6-anhydrosugars at the reducing terminal of antithrombin-binding octasaccharides isolated from low-molecular-weight heparin enoxaparin.

21 January 2018

1 reference

Determination of the primary structure and carboxyl pK (A)s of heparin-derived oligosaccharides by band-selective homonuclear-decoupled two-dimensional (1)H NMR.

21 January 2018

1 reference

Nuclear magnetic resonance of mass-limited samples using small RF coils

21 January 2018

1 reference

On-line NMR detection of microgram quantities of heparin-derived oligosaccharides and their structure elucidation by microcoil NMR.

21 January 2018

1 reference

Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney

21 January 2018

1 reference

Heparan sulfate phage display antibodies identify distinct epitopes with complex binding characteristics: insights into protein binding specificities

21 January 2018

1 reference

Heterogeneity of heparan sulfates in human lung

21 January 2018

1 reference

Localization and functional characterization of glycosaminoglycan domains in the normal human kidney as revealed by phage display-derived single chain antibodies.

21 January 2018

1 reference

Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera

21 January 2018

1 reference

Spatiotemporal distribution of heparan sulfate epitopes during myogenesis and synaptogenesis: a study in developing mouse intercostal muscle

21 January 2018

1 reference

Human single chain antibodies against heparin: selection, characterization, and effect on coagulation

21 January 2018

1 reference

Differential Expression of Heparan Sulfate Domains in Rat Spleen

21 January 2018

1 reference

Glycanogenomics: a qPCR-approach to investigate biological glycan function

21 January 2018

1 reference

Regulation of glycan structures in animal tissues: transcript profiling of glycan-related genes

21 January 2018

1 reference

Glycomics of proteoglycan biosynthesis in murine embryonic stem cell differentiation

21 January 2018

1 reference

Quantitative and qualitative alterations of heparan sulfate in fibrogenic liver diseases and hepatocellular cancer

21 January 2018

1 reference

Analysis of affinity and structural selectivity in the binding of proteins to glycosaminoglycans: development of a sensitive electrophoretic approach

21 January 2018

1 reference

A new strategy for defining critical functional groups on heparan sulfate

21 January 2018

1 reference

Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.

21 January 2018

1 reference

Bivalent and co-operative binding of complement factor H to heparan sulfate and heparin

21 January 2018

1 reference

Eotaxin selectively binds heparin. An interaction that protects eotaxin from proteolysis and potentiates chemotactic activity in vivo.

21 January 2018

1 reference

Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase

21 January 2018

1 reference

A surface plasmon resonance-based solution affinity assay for heparan sulfate-binding proteins

21 January 2018

1 reference

Kinetic studies on the interactions of heparin and complement proteins using surface plasmon resonance

21 January 2018

1 reference

The HIV-1 envelope glycoprotein gp120 features four heparan sulfate binding domains, including the co-receptor binding site.

21 January 2018

1 reference

A biophysical insight into the RANTES-glycosaminoglycan interaction

21 January 2018

1 reference

Different affinities of glycosaminoglycan oligosaccharides for monomeric and dimeric interleukin-8: a model for chemokine regulation at inflammatory sites

21 January 2018

1 reference

Active conformations of glycosaminoglycans. NMR determination of the conformation of heparin sequences complexed with antithrombin and fibroblast growth factors in solution

21 January 2018

1 reference

NMR structural studies of oligosaccharides related to cancer processes.

21 January 2018

1 reference

Conformational selection of the AGA*IA(M) heparin pentasaccharide when bound to the fibroblast growth factor receptor.

21 January 2018

1 reference

Structural view of glycosaminoglycan-protein interactions

21 January 2018

1 reference

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

21 January 2018

1 reference

Crystallographic analysis of calcium-dependent heparin binding to annexin A2.

21 January 2018

1 reference

Chemokine-glycosaminoglycan binding: specificity for CCR2 ligand binding to highly sulfated oligosaccharides using FTICR mass spectrometry

21 January 2018

1 reference

Effects of sulfate position on heparin octasaccharide binding to CCL2 examined by tandem mass spectrometry

21 January 2018

1 reference

Sulfated oligosaccharides (heparin and fucoidan) binding and dimerization of stromal cell-derived factor-1 (SDF-1/CXCL 12) are coupled as evidenced by affinity CE-MS analysis

21 January 2018

1 reference

Identification of heparin-binding sites in proteins by selective labeling

21 January 2018

1 reference

Heparin binding domain peptides of antithrombin III: analysis by isothermal titration calorimetry and circular dichroism spectroscopy

21 January 2018

1 reference

Circular dichroism spectroscopy of heparin-antithrombin interactions

21 January 2018

1 reference

Thermodynamic analysis of heparin binding to human antithrombin

21 January 2018

1 reference

Protein-GAG interactions: new surface-based techniques, spectroscopies and nanotechnology probes.

21 January 2018

1 reference

The interaction between heparin and Lys49 phospholipase A2 reveals the natural binding of heparin on the enzyme.

21 January 2018

1 reference

Evaluation of critical groups required for the binding of heparin to antithrombin

21 January 2018

1 reference

Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.

21 January 2018

1 reference

The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation

21 January 2018

1 reference

Microarrays of synthetic heparin oligosaccharides.

21 January 2018

1 reference

Signal amplification of target protein on heparin glycan microarray

21 January 2018

1 reference

Array-based functional screening of heparin glycans

21 January 2018

1 reference

Fabrication of carbohydrate microarrays on gold surfaces: direct attachment of nonderivatized oligosaccharides to hydrazide-modified self-assembled monolayers

21 January 2018

1 reference

A versatile gold surface approach for fabrication and interrogation of glycoarrays

21 January 2018

1 reference

Generating heparan sulfate saccharide libraries for glycomics applications.

21 January 2018

1 reference

Rapid purification and high sensitivity analysis of heparan sulfate from cells and tissues: toward glycomics profiling.

21 January 2018

1 reference

Automated solid-phase synthesis of oligosaccharides

21 January 2018

1 reference

Modular synthesis of heparin oligosaccharides

21 January 2018

1 reference

Highly diverse heparan sulfate analogue libraries: providing access to expanded areas of sequence space for bioactivity screening

21 January 2018

1 reference

Chemoenzymatic design of heparan sulfate oligosaccharides

21 January 2018

1 reference

Using an enzymatic combinatorial approach to identify anticoagulant heparan sulfate structures

21 January 2018

1 reference

Composition and structure elucidation of human milk glycosaminoglycans.

21 January 2018

1 reference

Identification of a candidate glycosaminoglycan-binding adhesin of the Lyme disease spirochete Borrelia burgdorferi

21 January 2018

1 reference

Decorin-binding adhesins from Borrelia burgdorferi.

21 January 2018

1 reference

Structure of the antithrombin-binding site in heparin

21 January 2018

1 reference

Mechanism of heparin activation of antithrombin. Role of individual residues of the pentasaccharide activating sequence in the recognition of native and activated states of antithrombin.

21 January 2018

1 reference

Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation

21 January 2018

1 reference

Cleavage of the antithrombin III binding site in heparin by heparinases and its implication in the generation of low molecular weight heparin

21 January 2018

1 reference

Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans

21 January 2018

1 reference

Antithrombin: in control of coagulation

21 January 2018

1 reference

Dermatan sulfate: new functions from an old glycosaminoglycan

21 January 2018

1 reference

Heparan sulfate fibroblast growth factor receptor complex: structure-function relationships

21 January 2018

1 reference

The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

21 January 2018

1 reference

Structural basis for fibroblast growth factor receptor activation

21 January 2018

1 reference

Receptor specificity of the fibroblast growth factor family

21 January 2018

1 reference

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

21 January 2018

1 reference

Insights into the role of heparan sulphate in fibroblast growth factor signalling

21 January 2018

1 reference

Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.

21 January 2018

1 reference

Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms

21 January 2018

1 reference

Highly sulfated nonreducing end-derived heparan sulfate domains bind fibroblast growth factor-2 with high affinity and are enriched in biologically active fractions

21 January 2018

1 reference

Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies

21 January 2018

1 reference

Biology of vascular endothelial growth factors

21 January 2018

1 reference

VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase

21 January 2018

1 reference

Binding affinities of vascular endothelial growth factor (VEGF) for heparin-derived oligosaccharides

21 January 2018

1 reference

Synthetic heparan sulfate oligosaccharides inhibit endothelial cell functions essential for angiogenesis

21 January 2018

1 reference

Synthetic oligosaccharide stimulates and stabilizes angiogenesis: structure-function relationships and potential mechanisms

21 January 2018

1 reference

PI-88 and novel heparan sulfate mimetics inhibit angiogenesis.

21 January 2018

1 reference

Characterization of a heparan sulfate octasaccharide that binds to herpes simplex virus type 1 glycoprotein D.

21 January 2018

1 reference

Herpes simplex virus type-1 (HSV-1) entry into human mesenchymal stem cells is heavily dependent on heparan sulfate

21 January 2018

1 reference

Viral and Cellular Determinants of the Hepatitis C Virus Envelope-Heparan Sulfate Interaction

21 January 2018

1 reference

N- and 6-O-sulfated heparan sulfates mediate internalization of coxsackievirus B3 variant PD into CHO-K1 cells

21 January 2018

1 reference

Specificity and selectivity profile of EP217609: a new neutralizable dual-action anticoagulant that targets thrombin and factor Xa

21 January 2018

1 reference

Evaluation of a new heparin agent in percutaneous coronary intervention: results of the phase 2 evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) Trial

21 January 2018

1 reference

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

21 January 2018

1 reference

GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice

21 January 2018

1 reference

Eprodisate for the treatment of renal disease in AA amyloidosis.

21 January 2018

1 reference

Automated oligosaccharide synthesis

21 January 2018

1 reference

Antiatherosclerotic effect of an antibody that binds to extracellular matrix glycosaminoglycans

21 January 2018

1 reference

Structure-based design of decoy chemokines as a way to explore the pharmacological potential of glycosaminoglycans.

21 January 2018

1 reference

Engineering the glycosaminoglycan-binding affinity, kinetics and oligomerization behavior of RANTES: a tool for generating chemokine-based glycosaminoglycan antagonists.

21 January 2018

1 reference

A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis

21 January 2018

1 reference

Following Protein–Glycosaminoglycan Polysaccharide Interactions with Differential Scanning Fluorimetry

21 January 2018

1 reference

Heparan sulphate epitope-expression is associated with the inflammatory response in metastatic malignant melanoma

21 January 2018

1 reference

A New Monocyte Chemotactic Protein-1/Chemokine CC Motif Ligand-2 Competitor Limiting Neointima Formation and Myocardial Ischemia/Reperfusion Injury in Mice

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/EPR.12.75

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414361%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414361%20AND%20SRC:MED&resulttype=core&format=json