(Q38095502)

28 August 2017

title

A daunting task: manipulating leukocyte function with RNAi (English)

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28 August 2017

1

Dan Peer

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28 August 2017

publication date

1 May 2013

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28 August 2017

published in

Immunological Reviews

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28 August 2017

volume

253

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28 August 2017

issue

1

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28 August 2017

page(s)

185-197

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

28 August 2017

cites work

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Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation

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RNA inhibition highlights cyclin D1 as a potential therapeutic target for mantle cell lymphoma

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Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

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In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

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Downregulation of monocyte chemoattractant protein-1 involving short interfering RNA attenuates hapten-induced contact hypersensitivity

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T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

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Targeted Delivery of Small Interfering RNA to Human Dendritic Cells To Suppress Dengue Virus Infection and Associated Proinflammatory Cytokine Production

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Transvascular delivery of small interfering RNA to the central nervous system.

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Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1.

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Adhesion receptors of the immune system

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Integrins: bidirectional, allosteric signaling machines

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Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation

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Induction of therapeutic gene silencing in leukocyte-implicated diseases by targeted and stabilized nanoparticles: a mini-review.

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Dynamic partitioning into lipid rafts controls the endo-exocytic cycle of the alphaL/beta2 integrin, LFA-1, during leukocyte chemotaxis

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Conformational regulation of integrin structure and function

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Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles

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Altering the immune response with lipid-based nanoparticles.

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Hyaluronan is a key component in cryoprotection and formulation of targeted unilamellar liposomes

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Loading mitomycin C inside long circulating hyaluronan targeted nano-liposomes increases its antitumor activity in three mice tumor models

21 January 2018

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Tumor-targeted hyaluronan nanoliposomes increase the antitumor activity of liposomal Doxorubicin in syngeneic and human xenograft mouse tumor models

21 January 2018

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Polysaccharides as building blocks for nanotherapeutics

21 January 2018

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Hyaluronan-coated nanoparticles: the influence of the molecular weight on CD44-hyaluronan interactions and on the immune response.

21 January 2018

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Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells

21 January 2018

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Targeting cyclins and cyclin-dependent kinases in cancer: lessons from mice, hopes for therapeutic applications in human

21 January 2018

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Cyclin D1: polymorphism, aberrant splicing and cancer risk

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Minireview: Cyclin D1: normal and abnormal functions

21 January 2018

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Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression

21 January 2018

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Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes

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Targeting Stat3 in cancer therapy

21 January 2018

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Cyclin D1 in breast cancer pathogenesis

21 January 2018

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Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics

21 January 2018

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Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

21 January 2018

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The RB and p53 pathways in cancer

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Pathogenesis of mantle-cell lymphoma: all oncogenic roads lead to dysregulation of cell cycle and DNA damage response pathways

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Antibody-mediated delivery of siRNAs for anti-HIV therapy

21 January 2018

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Molecular biology. The art of assembly

21 January 2018

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Hyaluronan-grafted particle clusters loaded with Mitomycin C as selective nanovectors for primary head and neck cancers

21 January 2018

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Hyaluronan grafted lipid-based nanoparticles as RNAi carriers for cancer cells

21 January 2018

1 reference

Role of Toll-like receptors in antisense and siRNA [corrected].

21 January 2018

1 reference

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

21 January 2018

1 reference

Activation of the interferon system by short-interfering RNAs

21 January 2018

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

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Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses

21 January 2018

1 reference

Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization

21 January 2018

1 reference

siRNA and isRNA: two edges of one sword

21 January 2018

1 reference

Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification

21 January 2018

1 reference

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

21 January 2018

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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

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Nanomedicine based approaches for the delivery of siRNA in cancer

21 January 2018

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Cationic liposomes as vaccine adjuvants

21 January 2018

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Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design

21 January 2018

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Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery

21 January 2018

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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

21 January 2018

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Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer.

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Assessing cellular toxicities in fibroblasts upon exposure to lipid-based nanoparticles: a high content analysis approach

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Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair

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21 January 2018

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21 January 2018

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Accelerated clearance of a second injection of PEGylated liposomes in mice

21 January 2018

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Alendronate liposomes for antitumor therapy: activation of γδ T cells and inhibition of tumor growth

21 January 2018

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Liposome-cell interactions in vitro: effect of liposome surface charge on the binding and endocytosis of conventional and sterically stabilized liposomes

21 January 2018

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Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition

21 January 2018

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Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver

21 January 2018

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Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy.

21 January 2018

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Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery

21 January 2018

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Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth

21 January 2018

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On future's doorstep: RNA interference and the pharmacopeia of tomorrow

21 January 2018

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Sustained small interfering RNA delivery by mesoporous silicon particles

21 January 2018

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Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA.

21 January 2018

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Nanoparticle hydrophobicity dictates immune response

21 January 2018

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Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction

21 January 2018

1 reference

Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/IMR.12044

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28 August 2017

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