(Q38102786)

28 August 2017

title

Antiglaucoma carbonic anhydrase inhibitors: a patent review (English)

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28 August 2017

3

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28 August 2017

Fabrizio Carta

2

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Claudiu T Supuran

series ordinal

4

object named as

Claudiu T Supuran

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28 August 2017

Emanuela Masini

1

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28 August 2017

language of work or name

English

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publication date

30 April 2013

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Expert Opinion on Therapeutic Patents

28 August 2017

published in

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28 August 2017

volume

23

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28 August 2017

issue

6

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28 August 2017

page(s)

705-716

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Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma

28 August 2017

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Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

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Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?

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Structure-based drug discovery of carbonic anhydrase inhibitors

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Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds.

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The first activation study of a bacterial carbonic anhydrase (CA). The thermostable α-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines.

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The development of topically acting carbonic anhydrase inhibitors as anti-glaucoma agents

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Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma

21 January 2018

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Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors

21 January 2018

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Irreversible corneal decompensation in patients treated with topical dorzolamide

21 January 2018

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Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.

21 January 2018

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Synthesis of novel nitric oxide (NO)-releasing esters of timolol

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Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma

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Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action

21 January 2018

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Carbonic anhydrase inhibitors and activators for novel therapeutic applications

21 January 2018

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Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulphonamides

21 January 2018

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Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule

21 January 2018

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Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors

21 January 2018

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Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins

21 January 2018

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Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.

21 January 2018

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Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations

21 January 2018

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Dithiocarbamates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Action in Vivo

21 January 2018

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21 January 2018

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21 January 2018

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1α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor

21 January 2018

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1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates

21 January 2018

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α-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters

21 January 2018

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Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases

21 January 2018

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21 January 2018

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21 January 2018

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DNA Cloning, Characterization, and Inhibition Studies of an α-Carbonic Anhydrase from the Pathogenic Bacterium Vibrio cholerae

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Carbonic Anhydrase Inhibitors. Synthesis of Water-Soluble, Topically Effective, Intraocular Pressure-Lowering Aromatic/Heterocyclic Sulfonamides Containing Cationic or Anionic Moieties: Is the Tail More Important than the Ring?1

21 January 2018

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Carbonic Anhydrase Inhibitors: Synthesis of Water-Soluble, Aminoacyl/Dipeptidyl Sulfonamides Possessing Long-Lasting Intraocular Pressure-Lowering Properties via the Topical Route1

21 January 2018

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Carbonic Anhydrase Inhibitors: Perfluoroalkyl/Aryl-Substituted Derivatives of Aromatic/Heterocyclic Sulfonamides as Topical Intraocular Pressure-Lowering Agents with Prolonged Duration of Action

21 January 2018

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Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata

21 January 2018

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10.1517/13543776.2013.794788

21 January 2018

Identifiers

DOI

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28 August 2017

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