(Q38134049)

29 August 2017

title

Poly(ADP-ribose) polymerase 1 (PARP1) in atherosclerosis: from molecular mechanisms to therapeutic implications (English)

1 reference

29 August 2017

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3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24002940%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Pei-Qing Liu

series ordinal

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24002940%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Suowen Xu

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24002940%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Peter Bai

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24002940%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

publication date

3 September 2013

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Medicinal Research Reviews

29 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24002940%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24002940%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24002940%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

644-675

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24002940%20AND%20SRC:MED&resulttype=core&format=json

Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

12 June 2020

cites work

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The pathogenesis of atherosclerosis: a perspective for the 1990s

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Morphologic features of unstable atherothrombotic plaques underlying acute coronary syndromes

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Stability and instability: two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995.

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Pharmacotherapy of coronary atherosclerosis

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Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications

21 January 2018

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Hyperelongated biglycan: the surreptitious initiator of atherosclerosis

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Cellular and cytokine-based inflammatory processes as novel therapeutic targets for the prevention and treatment of atherosclerosis

21 January 2018

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Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

21 January 2018

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Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell dea

21 January 2018

1 reference

Nicotinamide mononucleotide activation of a new DNA-dependent polyadenylic acid synthesizing nuclear enzyme

21 January 2018

1 reference

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites

21 January 2018

1 reference

Poly(ADP-ribose)-polymerase-catalyzed hydrolysis of NAD+: QM/MM simulation of the enzyme reaction

21 January 2018

1 reference

Size and shape of poly(ADP-ribose): examination by gel filtration, gel electrophoresis and electron microscopy

21 January 2018

1 reference

21 January 2018

1 reference

In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)

21 January 2018

1 reference

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

21 January 2018

1 reference

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

21 January 2018

1 reference

Coenzymatic activity of randomly broken or intact double-stranded DNAs in auto and histone H1 trans-poly(ADP-ribosylation), catalyzed by poly(ADP-ribose) polymerase (PARP I).

21 January 2018

1 reference

Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-2 depletion reduces doxorubicin-induced damage through SIRT1 induction.

21 January 2018

1 reference

Mass spectrometry-based functional proteomics of poly(ADP-ribose) polymerase-1.

21 January 2018

1 reference

Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry

21 January 2018

1 reference

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases.

21 January 2018

1 reference

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation

21 January 2018

1 reference

The diverse roles and clinical relevance of PARPs in DNA damage repair: current state of the art.

21 January 2018

1 reference

Role of poly(ADP-ribose) polymerases in the regulation of inflammatory processes

21 January 2018

1 reference

The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy

21 January 2018

1 reference

Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors

21 January 2018

1 reference

Inhibitors of poly(adenosine diphosphate-ribose) synthesis: effect on other metabolic processes

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-2: emerging transcriptional roles of a DNA-repair protein

21 January 2018

1 reference

PARP-2 regulates SIRT1 expression and whole-body energy expenditure

21 January 2018

1 reference

Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques

21 January 2018

1 reference

iNOS induction and PARP-1 activation in human atherosclerotic lesions: an immunohistochemical and ultrastructural approach

21 January 2018

1 reference

Inhibition of the activity of poly (ADP-ribose) polymerase reduces heart ischaemia/reperfusion injury via suppressing JNK-mediated AIF translocation

21 January 2018

1 reference

Poly(ADP-ribose) polymerase 1 inhibition protects human aortic endothelial cells against LPS-induced inflammation response.

21 January 2018

1 reference

Poly(ADP-ribose) polymerase inhibition prevents homocysteine-induced endothelial dysfunction in the isolated rat aorta

21 January 2018

1 reference

Poly (ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by hyperhomocysteinemia in rats

21 January 2018

1 reference

Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

21 January 2018

1 reference

Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation

21 January 2018

1 reference

Poly(ADP-ribose) polymerase 1 inhibition protects against low shear stress induced inflammation

21 January 2018

1 reference

Poly(ADP-Ribose) polymerase inhibition improves endothelial dysfunction induced by hypochlorite

21 January 2018

1 reference

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-1 (PARP-1) and its therapeutic implications

21 January 2018

1 reference

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

21 January 2018

1 reference

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)

21 January 2018

1 reference

Inflammation in atherosclerosis

21 January 2018

1 reference

PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes.

21 January 2018

1 reference

Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation

21 January 2018

1 reference

Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism

21 January 2018

1 reference

The macroPARP genes Parp-9 and Parp-14 are developmentally and differentially regulated in mouse tissues.

21 January 2018

1 reference

Poly (ADP-ribose) polymerase 14 and its enzyme activity regulates T(H)2 differentiation and allergic airway disease

21 January 2018

1 reference

PARP-14 functions as a transcriptional switch for Stat6-dependent gene activation

21 January 2018

1 reference

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

21 January 2018

1 reference

Regulation of transcription factor NFAT by ADP-ribosylation

21 January 2018

1 reference

Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells.

21 January 2018

1 reference

Activator protein-1 signalling pathway and apoptosis are modulated by poly(ADP-ribose) polymerase-1 in experimental colitis

21 January 2018

1 reference

Genetic ablation of PARP-1 protects against oxazolone-induced contact hypersensitivity by modulating oxidative stress

21 January 2018

1 reference

Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia

21 January 2018

1 reference

Interaction of the transcription factor YY1 with human poly(ADP-ribosyl) transferase.

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia

21 January 2018

1 reference

Prolonged poly(ADP-ribose) polymerase-1 activity regulates JP-8-induced sustained cytokine expression in alveolar macrophages

21 January 2018

1 reference

Enhanced NF-κB activity impairs vascular function through PARP-1-, SP-1-, and COX-2-dependent mechanisms in type 2 diabetes.

21 January 2018

1 reference

Mechanical stretch enhances NF-kappaB-dependent gene expression and poly(ADP-ribose) synthesis in synovial cells

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation

21 January 2018

1 reference

Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes.

21 January 2018

1 reference

Opposing roles of PARP-1 in MMP-9 and TIMP-2 expression and mast cell degranulation in dyslipidemic dilated cardiomyopathy

21 January 2018

1 reference

Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

21 January 2018

1 reference

A randomized, placebo-controlled trial to evaluate the tolerability, safety, pharmacokinetics, and pharmacodynamics of a potent inhibitor of poly(ADP-ribose) polymerase (INO-1001) in patients with ST-elevation myocardial infarction undergoing primar

21 January 2018

1 reference

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

21 January 2018

1 reference

Toward specific functions of poly(ADP-ribose) polymerase-2.

21 January 2018

1 reference

Sirtuin 1 and sirtuin 3: physiological modulators of metabolism

21 January 2018

1 reference

Franklin H. Epstein Lecture: Sirtuins, aging, and medicine

21 January 2018

1 reference

The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity

21 January 2018

1 reference

Cloning and characterization of four SIR genes of Saccharomyces cerevisiae

21 January 2018

1 reference

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

1 reference

Seven sirtuins for seven deadly diseases of aging

21 January 2018

1 reference

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways

21 January 2018

1 reference

Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?

21 January 2018

1 reference

Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes

21 January 2018

1 reference

SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism

21 January 2018

1 reference

21 January 2018

Sirtuins at a glance.

1 reference

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

1 reference

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

21 January 2018

1 reference

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

21 January 2018

1 reference

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

21 January 2018

1 reference

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

21 January 2018

1 reference

The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease

21 January 2018

1 reference

Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked?

21 January 2018

1 reference

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

21 January 2018

1 reference

Serum or target deprivation-induced neuronal death causes oxidative neuronal accumulation of Zn2+ and loss of NAD+.

21 January 2018

1 reference

Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons

21 January 2018

1 reference

Preventing NAD(+) depletion protects neurons against excitotoxicity: bioenergetic effects of mild mitochondrial uncoupling and caloric restriction

21 January 2018

1 reference

SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1

21 January 2018

1 reference

Identification of the Aryl Hydrocarbon Receptor Target Gene TiPARP as a Mediator of Suppression of Hepatic Gluconeogenesis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and of Nicotinamide as a Corrective Agent for This Effect

21 January 2018

1 reference

SIRT1: new avenues of discovery for disorders of oxidative stress

21 January 2018

1 reference

Regulation of SIRT1 in cellular functions: role of polyphenols

21 January 2018

1 reference

Vascular smooth muscle cell sirtuin 1 protects against DNA damage and inhibits atherosclerosis

21 January 2018

1 reference

Restoration of the endothelial function in the aortic rings of apolipoprotein E deficient mice by pharmacological inhibition of the nuclear enzyme poly(ADP-ribose) polymerase

21 January 2018

1 reference

Crosstalk between components of circadian and metabolic cycles in mammals

21 January 2018

1 reference

Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging

21 January 2018

1 reference

PARP1 is required for adhesion molecule expression in atherogenesis

21 January 2018

1 reference

The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders

21 January 2018

1 reference

The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function

21 January 2018

1 reference

Negative regulation of inflammation by SIRT1.

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.

21 January 2018

1 reference

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

21 January 2018

1 reference

Protective effects of PARP-1 knockout on dyslipidemia-induced autonomic and vascular dysfunction in ApoE mice: effects on eNOS and oxidative stress

21 January 2018

1 reference

Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1.

21 January 2018

1 reference

21 January 2018

1 reference

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

21 January 2018

1 reference

Interference between PARPs and SIRT1: a novel approach to healthy ageing?

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-2 [corrected] controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the retinoid X receptor/peroxisome proliferator-activated receptor-gamma [corrected] heterodimer

21 January 2018

1 reference

Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury

21 January 2018

1 reference

Poly(ADP-ribose) polymerase 1 inhibition improves coronary arteriole function in type 2 diabetes mellitus.

21 January 2018

1 reference

Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure

21 January 2018

1 reference

A new, potent poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging

21 January 2018

1 reference

Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation

21 January 2018

1 reference

Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite

21 January 2018

1 reference

Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells

21 January 2018

1 reference

Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease

21 January 2018

1 reference

Nitric oxide and peroxynitrite in health and disease

21 January 2018

1 reference

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

21 January 2018

1 reference

Selective pharmacological inhibition of distinct nitric oxide synthase isoforms

21 January 2018

1 reference

Poly (ADP-Ribose) polymerase inhibition attenuates atherosclerotic plaque development in ApoE-/- mice with hyperhomocysteinemia

21 January 2018

1 reference

Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-κB activation.

21 January 2018

1 reference

Differential effects of PARP inhibition on vascular cell survival and ACAT-1 expression favouring atherosclerotic plaque stability

21 January 2018

1 reference

Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content

21 January 2018

1 reference

SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

21 January 2018

1 reference

PARP inhibition in atherosclerosis and its effects on dendritic cells, T cells and auto-antibody levels

21 January 2018

1 reference

LOX-1 in atherosclerosis: biological functions and pharmacological modifiers.

21 January 2018

1 reference

Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.

21 January 2018

1 reference

Minocycline reduces plaque size in diet induced atherosclerosis via p27(Kip1).

21 January 2018

1 reference

Poly(ADP-ribose) polymerase 1 is indispensable for transforming growth factor-β Induced Smad3 activation in vascular smooth muscle cell

21 January 2018

1 reference

Glucagon-like peptide 1 protects microvascular endothelial cells by inactivating the PARP-1/iNOS/NO pathway

21 January 2018

1 reference

Poly (ADP) ribose synthetase inhibition in alveolar macrophages undergoing hypoxia and reoxygenation

21 January 2018

1 reference

Effect of an antimicrobial agent on atherosclerotic plaques: assessment of metalloproteinase activity by molecular imaging

21 January 2018

1 reference

Chlamydia pneumoniae infection induces differentiation of monocytes into macrophages

21 January 2018

1 reference

Novel modulators of poly(ADP-ribose) polymerase

21 January 2018

1 reference

Non-antibacterial tetracyclines modulate mediators of periodontitis and atherosclerotic cardiovascular disease: a mechanistic link between local and systemic inflammation

21 January 2018

1 reference

Identification of pim kinases as novel targets for PJ34 with confounding effects in PARP biology.

21 January 2018

1 reference

Poly(ADP-ribose) polymerase inhibitors

21 January 2018

1 reference

Inhibition of matrix metalloproteinase-2 by PARP inhibitors

21 January 2018

1 reference

Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase

21 January 2018

1 reference

Attenuation of neointima formation through the inhibition of DNA repair enzyme PARP-1 in balloon-injured rat carotid artery

21 January 2018

1 reference

PARP inhibitors: polypharmacology versus selective inhibition

21 January 2018

1 reference

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

21 January 2018

1 reference

Doxycycline modulates smooth muscle cell growth, migration, and matrix remodeling after arterial injury

21 January 2018

1 reference

Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms.

21 January 2018

1 reference

Clinical and biochemical results of the metalloproteinase inhibition with subantimicrobial doses of doxycycline to prevent acute coronary syndromes (MIDAS) pilot trial.

21 January 2018

1 reference

Matrix metalloproteinase inhibition with tetracyclines for the treatment of coronary artery disease

21 January 2018

1 reference

The emerging role of poly(ADP-Ribose) polymerase inhibitors in cancer treatment

21 January 2018

1 reference

PARP inhibition: PARP1 and beyond

21 January 2018

1 reference

Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome

21 January 2018

1 reference

Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress

21 January 2018

1 reference

Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites

21 January 2018

1 reference

Insulin Resistance and Atherosclerosis

21 January 2018

1 reference