(Q38165759)

30 August 2017

Animal models of neurodegenerative diseases (English)

1 reference

30 August 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24271230%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Leonardo C de Souza

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24271230%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Antonio L Teixeira

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24271230%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Elizabeth Ribeiro da Silva Camargos

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24271230%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

1 January 2013

1 reference

Brazilian Journal of Psychiatry

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24271230%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

35 Suppl 2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24271230%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

S82-91

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24271230%20AND%20SRC:MED&resulttype=core&format=json

The worldwide societal costs of dementia: Estimates for 2009.

8 June 2020

cites work

1 reference

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21 January 2018

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Alzheimer disease models and human neuropathology: similarities and differences

21 January 2018

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21 January 2018

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Pathways by which Abeta facilitates tau pathology

21 January 2018

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Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

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Classification and basic pathology of Alzheimer disease

21 January 2018

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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

21 January 2018

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Amyloid-dependent and amyloid-independent stages of Alzheimer disease

21 January 2018

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

21 January 2018

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Alzheimer's disease is a synaptic failure

21 January 2018

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Rodent models of Alzheimer's disease: rat A beta infusion approaches to amyloid deposits

21 January 2018

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Animal models in the drug discovery pipeline for Alzheimer's disease

21 January 2018

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Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpressing mutant APPSWE

21 January 2018

1 reference

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Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

21 January 2018

1 reference

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Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

21 January 2018

1 reference

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A decade of tau transgenic animal models and beyond

21 January 2018

1 reference

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Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

21 January 2018

1 reference

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Abeta inhibits the proteasome and enhances amyloid and tau accumulation

21 January 2018

1 reference

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Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

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Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Regulation of NMDA receptor trafficking by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Skeletal and CNS defects in Presenilin-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

1 reference

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APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.

21 January 2018

1 reference

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Analysis of Protein Domain Families inCaenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

21 January 2018

1 reference

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Geographic and ethnic variation in Parkinson disease: a population-based study of US Medicare beneficiaries.

21 January 2018

1 reference

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Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease

21 January 2018

1 reference

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Parkinson's disease: clinical features and diagnosis

21 January 2018

1 reference

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21 January 2018

1 reference

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Stages in the development of Parkinson's disease-related pathology

21 January 2018

1 reference

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Missing pieces in the Parkinson's disease puzzle

21 January 2018

1 reference

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A guide to neurotoxic animal models of Parkinson's disease

21 January 2018

1 reference

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Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease

21 January 2018

1 reference

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A tale on animal models of Parkinson's disease

21 January 2018

1 reference

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Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

21 January 2018

1 reference

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Manganese decreases glutamate uptake in cultured astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

MPTP as a mitochondrial neurotoxic model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Modeling Parkinson's disease in primates: The MPTP model

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

From the MPTP-treated primate to the treatment of motor complications in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

The intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a new rodent model to test palliative and neuroprotective agents for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

The role of oxidative stress, impaired glycolysis and mitochondrial respiratory redox failure in the cytotoxic effects of 6-hydroxydopamine in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Inflammation and adaptive immunity in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Genomics and bioinformatics of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Increased serum levels of soluble tumor necrosis factor-alpha receptor-1 in patients with Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

The lipopolysaccharide Parkinson's disease animal model: mechanistic studies and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Huntingtin-protein interactions and the pathogenesis of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Huntingtin in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 January 2018

1 reference

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Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Clinical and neuropathologic assessment of severity in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Neurological abnormalities in a knock-in mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Mouse models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.

21 January 2018

1 reference

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Apoptosis in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Apoptosis in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Influence of species differences on the neuropathology of transgenic Huntington's disease animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

A putative Drosophila homolog of the Huntington's disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Learning and memory in Drosophila: behavior, genetics, and neural systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157

Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2F1516-4446-2013-1157