(Q38329422)

2 September 2017

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title

Integrating autophagy and metabolism in cancer (English)

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2 September 2017

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Heesun Cheong

1

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2 September 2017

publication date

24 January 2015

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Archives of Pharmacal Research

2 September 2017

published in

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2 September 2017

volume

38

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2 September 2017

issue

3

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2 September 2017

page(s)

358-371

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Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy restricts proliferation driven by oncogenic phosphatidylinositol 3-kinase in three-dimensional culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Therapeutic targets in cancer cell metabolism and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy positively regulates the CD44(+) CD24(-/low) breast cancer stem-like phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

The nutritional phenome of EMT-induced cancer stem-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Glutaminolysis activates Rag-mTORC1 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

The machinery of macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Metabolic control of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy is required for glucose homeostasis and lung tumor maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Cellular and metabolic functions for autophagy in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy and the integrated stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Cell surface glycan alterations in epithelial mesenchymal transition process of Huh7 hepatocellular carcinoma cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy and cancer--issues we need to digest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Ras, autophagy and glycolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy and cancer cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

DEDD, a novel tumor repressor, reverses epithelial-mesenchymal transition by activating selective autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

PKM2 and the tricky balance of growth and energy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Dynamics and diversity in autophagy mechanisms: lessons from yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Bidirectional transport of amino acids regulates mTOR and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Regulation of cell proliferation and migration by p62 through stabilization of Twist1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Role of glutamine in cancer: therapeutic and imaging implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Combined MTOR and autophagy inhibition: phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

p53 status determines the role of autophagy in pancreatic tumour development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

The glycolytic enzyme PFKFB3/phosphofructokinase regulates autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Atg22 recycles amino acids to link the degradative and recycling functions of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0562-2

10.1007/S12272-015-0562-2

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

2 September 2017

1027085245

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1 reference