(Q38335714)

2 September 2017

2 references

1 May 2021

Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs (English)

1 reference

2 September 2017

1 reference

1 May 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25630541%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Dimitris Lagos

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25630541%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Michael J Plevin

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25630541%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

2

Dimitris Lagos

1 reference

2 September 2017

Alex Heyam

1

1 reference

25630541

2 September 2017

Michael Plevin

series ordinal

3

1 reference

25630541

2 September 2017

language of work or name

1 reference

28 January 2015

2 references

Wiley interdisciplinary reviews. RNA

2 September 2017

1 May 2021

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25630541%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 May 2021

6

1 reference

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1 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25630541%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

271-289

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25630541%20AND%20SRC:MED&resulttype=core&format=json

Biogenesis of small RNAs in animals

1 June 2020

cites work

1 reference

The response of mammalian cells to double-stranded RNA

21 January 2018

1 reference

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

21 January 2018

1 reference

PACT, a protein activator of the interferon-induced protein kinase, PKR.

21 January 2018

1 reference

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

21 January 2018

1 reference

TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

21 January 2018

1 reference

A conserved double-stranded RNA-binding domain

21 January 2018

1 reference

Modular structure of PACT: distinct domains for binding and activating PKR

21 January 2018

1 reference

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

21 January 2018

1 reference

Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs

21 January 2018

1 reference

Crystal structure of human DGCR8 core

21 January 2018

1 reference

A human sequence homologue of Staufen is an RNA-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum

21 January 2018

1 reference

The double-stranded RNA-binding motif, a versatile macromolecular docking platform

21 January 2018

1 reference

RNA-binding proteins: modular design for efficient function

21 January 2018

1 reference

Multiple sequence alignment with hierarchical clustering

21 January 2018

1 reference

ESPript/ENDscript: Extracting and rendering sequence and 3D information from atomic structures of proteins

21 January 2018

1 reference

Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III.

21 January 2018

1 reference

Structure of RDE-4 dsRBDs and mutational studies provide insights into dsRNA recognition in the Caenorhabditis elegans RNAi pathway

21 January 2018

1 reference

The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans

21 January 2018

1 reference

The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domains

21 January 2018

1 reference

Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein

21 January 2018

1 reference

RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA.

21 January 2018

1 reference

dsRNA binding properties of RDE-4 and TRBP reflect their distinct roles in RNAi

21 January 2018

1 reference

Distinguishable in vitro binding mode of monomeric TRBP and dimeric PACT with siRNA

21 January 2018

1 reference

Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR

21 January 2018

1 reference

Staufen1 senses overall transcript secondary structure to regulate translation

21 January 2018

1 reference

RNA editing by adenosine deaminases that act on RNA

21 January 2018

1 reference

RNA recognition by a Staufen double-stranded RNA-binding domain

21 January 2018

1 reference

Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay

21 January 2018

1 reference

'Black sheep' that don't leave the double-stranded RNA-binding domain fold

21 January 2018

1 reference

In vitro reconstitution of the human RISC-loading complex

21 January 2018

1 reference

Characterization of the TRBP domain required for dicer interaction and function in RNA interference

21 January 2018

1 reference

The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity

21 January 2018

1 reference

Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity

21 January 2018

1 reference

The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo

21 January 2018

1 reference

Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain

21 January 2018

1 reference

Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop.

21 January 2018

1 reference

Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions

21 January 2018

1 reference

Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation

21 January 2018

1 reference

Increased interaction between PACT molecules in response to stress signals is required for PKR activation.

21 January 2018

1 reference

Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression

21 January 2018

1 reference

Biochemical principles of small RNA pathways

21 January 2018

1 reference

Small RNAs as guardians of the genome

21 January 2018

1 reference

Recognition of siRNA asymmetry by TAR RNA binding protein.

21 January 2018

1 reference

Multiple sensors ensure guide strand selection in human RNAi pathways

21 January 2018

1 reference

Widespread regulatory activity of vertebrate microRNA* species

21 January 2018

1 reference

Deep-sequencing of human Argonaute-associated small RNAs provides insight into miRNA sorting and reveals Argonaute association with RNA fragments of diverse origin.

21 January 2018

1 reference

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

1 reference

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

21 January 2018

1 reference

The role of PACT in the RNA silencing pathway

21 January 2018

1 reference

Structural basis for double-stranded RNA processing by Dicer

21 January 2018

1 reference

Substrate-specific kinetics of Dicer-catalyzed RNA processing

21 January 2018

1 reference

Ribonuclease activity and RNA binding of recombinant human Dicer

21 January 2018

1 reference

ATP-dependent human RISC assembly pathways

21 January 2018

1 reference

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

21 January 2018

1 reference

MicroRNA biogenesis and cancer

21 January 2018

1 reference

RETRACTED: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

21 January 2018

1 reference

The activity and expression of microRNAs in prostate cancers

21 January 2018

1 reference

Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma

21 January 2018

1 reference

Up-regulation and worse prognostic marker of cytoplasmic TARBP2 expression in obstinate breast cancer

21 January 2018

1 reference

Structure of the human Dicer-TRBP complex by electron microscopy

21 January 2018

1 reference

The molecular architecture of human Dicer

21 January 2018

1 reference

Structural insights into RNA processing by the human RISC-loading complex

21 January 2018

1 reference

RNA helicase A interacts with RISC in human cells and functions in RISC loading

21 January 2018

1 reference

Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies

21 January 2018

1 reference

Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

21 January 2018

1 reference

Enoxacin inhibits growth of prostate cancer cells and effectively restores microRNA processing.

21 January 2018

1 reference

Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer

21 January 2018

1 reference

Structural determinants of RNA recognition and cleavage by Dicer

21 January 2018

1 reference

Autoinhibition of human dicer by its internal helicase domain

21 January 2018

1 reference

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

21 January 2018

1 reference

Substrate-specific structural rearrangements of human Dicer

21 January 2018

1 reference

siRNA repositioning for guide strand selection by human Dicer complexes

21 January 2018

1 reference

TRBP alters human precursor microRNA processing in vitro

21 January 2018

1 reference

Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing

21 January 2018

1 reference

Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA

21 January 2018

1 reference

IsomiRs--the overlooked repertoire in the dynamic microRNAome.

21 January 2018

1 reference

The role of Dicer protein partners in the processing of microRNA precursors

21 January 2018

1 reference

Dicer partner proteins tune the length of mature miRNAs in flies and mammals

21 January 2018

1 reference

RNA interference directs innate immunity against viruses in adult Drosophila

21 January 2018

1 reference

Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells

21 January 2018

1 reference

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

21 January 2018

1 reference

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

21 January 2018

1 reference

A protein sensor for siRNA asymmetry

21 January 2018

1 reference

Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

21 January 2018

1 reference

Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

21 January 2018

1 reference

Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences

21 January 2018

1 reference

Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila

21 January 2018

1 reference

Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

21 January 2018

1 reference

The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells

21 January 2018

1 reference

RAX is required for fly neuronal development and mouse embryogenesis.

21 January 2018

1 reference

ATP-independent diffusion of double-stranded RNA binding proteins

21 January 2018

1 reference

Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling

21 January 2018

1 reference

Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

Intracellular localization and routing of miRNA and RNAi pathway components

21 January 2018

1 reference

Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells

21 January 2018

1 reference

MicroRNA silencing through RISC recruitment of eIF6

21 January 2018

1 reference

The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

21 January 2018

1 reference

Traffic into silence: endomembranes and post-transcriptional RNA silencing

21 January 2018

1 reference

The chase for the RIG-I ligand--recent advances

21 January 2018

1 reference

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

21 January 2018

1 reference

Structural Insights into RNA Recognition by RIG-I

21 January 2018

1 reference

A structure-based model of RIG-I activation

21 January 2018

1 reference

RNA recognition and signal transduction by RIG-I-like receptors

21 January 2018

1 reference

MDA5/RIG-I and virus recognition.

21 January 2018

1 reference

Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome

21 January 2018

1 reference

Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response.

21 January 2018

1 reference

SF1 and SF2 helicases: family matters

21 January 2018

1 reference

PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus.

21 January 2018

1 reference

Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein

21 January 2018

1 reference

Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein.

21 January 2018

1 reference

Ebolavirus proteins suppress the effects of small interfering RNA by direct interaction with the mammalian RNA interference pathway

21 January 2018

1 reference

Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network

21 January 2018

1 reference

The cellular TAR RNA binding protein, TRBP, promotes HIV-1 replication primarily by inhibiting the activation of double-stranded RNA-dependent kinase PKR.

21 January 2018

1 reference

A re-examination of global suppression of RNA interference by HIV-1.

21 January 2018

1 reference

The role of PACT in mediating gene induction, PKR activation, and apoptosis in response to diverse stimuli

21 January 2018

1 reference

The eIF2α kinases: their structures and functions

21 January 2018

1 reference

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

21 January 2018

1 reference

Activation of PKR: an open and shut case?

21 January 2018

1 reference

Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2).

21 January 2018

1 reference

The dsRNA protein kinase PKR: virus and cell control

21 January 2018

1 reference

Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis

21 January 2018

1 reference

Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.

21 January 2018

1 reference

Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

21 January 2018

1 reference

Molecular basis for PKR activation by PACT or dsRNA

21 January 2018

1 reference

TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress

21 January 2018

1 reference

The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)

21 January 2018

1 reference

PACT-mediated enhancement of reporter gene expression at the translational level

21 January 2018

1 reference

Biochemical analysis of PKR activation by PACT.

21 January 2018

1 reference

Is RNA interference involved in intrinsic antiviral immunity in mammals?

21 January 2018

1 reference

RNA silencing in the antiviral innate immune defence--role of DEAD-box RNA helicases

21 January 2018

1 reference

A role of the double-stranded RNA-binding protein PACT in mouse ear development and hearing

21 January 2018

1 reference

DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA

21 January 2018

1 reference

Deletion of human tarbp2 reveals cellular microRNA targets and cell-cycle function of TRBP.

21 January 2018

1 reference

Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis

21 January 2018

1 reference

The TAR RNA-binding Protein, TRBP, Stimulates the Expression of TAR-containing RNAsin Vitroandin VivoIndependently of Its Ability to Inhibit the dsRNA-dependent Kinase PKR

21 January 2018

1 reference

DICER1 and PRKRA in Colon Adenocarcinoma.

21 January 2018

1 reference

12 December 2020

The Th2 transcription factor c-Maf inhibits IL-12p35 gene expression in activated macrophages by targeting NF-kappaB nuclear translocation

1 reference

12 December 2020

HIV-1 TAR RNA subverts RNA interference in transfected cells through sequestration of TAR RNA-binding protein, TRBP

1 reference

12 December 2020

The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response

1 reference

12 December 2020

RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence

1 reference

12 December 2020

Identifiers

DOI

10.1002/WRNA.1272

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25630541%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25630541%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

25630541

1 reference