(Q38340708)

English

Residence time distributions of solutes in the perfused rat liver using a dispersion model of hepatic elimination: 1. Effect of changes in perfusate flow and albumin concentration on sucrose and taurocholate

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

Residence time distributions of solutes in the perfused rat liver using a dispersion model of hepatic elimination: 1. Effect of changes in perfusate flow and albumin concentration on sucrose and taurocholate (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

author name string

M S Roberts

1

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

S Fraser

2

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

A Wagner

3

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

L McLeod

4

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 June 1990

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Europe PubMed Central

PubMed publication ID

2 September 2017

Journal of Pharmacokinetics and Pharmacodynamics

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Europe PubMed Central

PubMed publication ID

2 September 2017

18

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Europe PubMed Central

PubMed publication ID

2 September 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

209-234

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

https://scigraph.springernature.com/pub.10.1007/bf01062200

0 references

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

Hepatic clearance of drugs. II. Experimental evidence for acceptance of the “well-stirred” model over the “parallel tube” model using lidocaine in the perfused rat liverin situ preparation

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

Hepatic clearance of drugs. III. Additional experimental evidence supporting the "well-stirred" model, using metabolite (MEGX) generated from lidocaine under varying hepatic blood flow rates and linear conditions in the perfused rat liver in situ pr

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

Models of hepatic drug clearance: discrimination between the ‘well stirred’ and ‘parallel-tube’ models

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

Protein binding and hepatic clearance: discrimination between models of hepatic clearance with diazepam, a drug of high intrinsic clearance, in the isolated perfused rat liver preparation.

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

Hepatic elimination of flowing substrates: the distributed model

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

A dispersion model of hepatic elimination: 1. Formulation of the model and bolus considerations.

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

A dispersion model of hepatic elimination: 3. Application to metabolite formation and elimination kinetics.

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

Models of hepatic elimination: Comparison of stochastic models to describe residence time distributions and to predict the influence of drug distribution, enzyme heterogeneity, and systemic recycling on hepatic elimination

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

Physiologically based models and strategic experiments in hepatic pharmacology

1 reference

https://api.crossref.org/works/10.1007%2FBF01062200

21 January 2018

The effect of hepatic blood flow on taurocholate extraction by the isolated perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation from albumin: a potentially rate-limiting step in the clearance of substances by the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver blood flow. I. Intrinsic and nervous control of liver blood flow.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrahepatic distribution of hepatic blood flow: double-input studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Availability predictions by hepatic elimination models for Michaelis-Menten kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

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Uptake of bile acids by isolated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

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Liver blood flow. II. Effects of drugs and hormones on liver blood flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the relation between extended forms of the sinusoidal perfusion and of the convection-dispersion models of hepatic elimination

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flow dependence of propranolol elimination in perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional tissue uptake of deuterium oxide in perfused organs: rat liver, dog heart and gastrocnemius

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of Taurocholic Acid into Isolated Rat-Liver Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the bile acid transport system in normal and transformed hepatocytes. Photoaffinity labeling of the taurocholate carrier protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ligandin in transfer of bilirubin from plasma into liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saturation kinetics in hepatic drug removal: a statistical approach to functional heterogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of sinusoidal perfusion on galactose elimination kinetics in perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the sinusoidal transport process responsible for uptake of chylomicrons by the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoradiographic and kinetic demonstration of acinar heterogeneity of taurocholate transport.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of distribution of D2O and antipyrine in isolated perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of linear correlation between hepatic ligand uptake rate and unbound ligand concentration does not necessarily imply receptor-mediated uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic interpretation of hepatic multiple-indicator dilution studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of metabolite formation and elimination in the perfused rat liver preparation: differences between the elimination of preformed acetaminophen and acetaminophen formed from phenacetin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic bile acid transport: effect of conjugation and position of hydroxyl groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of albumin binding on extraction of sulfobromophthalein by perfused elasmobranch liver: evidence for dissociation-limited uptake.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of plasma protein binding on elimination of taurocholate by isolated perfused rat liver: comparison of venous equilibrium, undistributed and distributed sinusoidal, and dispersion models

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrahepatic distribution of hepatic blood flow: single-input studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A linear method for determining liver sinusoidal and extravascular volumes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Albumin does not mediate the removal of taurocholate by the rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Albumin helps mediate removal of taurocholate by rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discrimination between the venous equilibrium and sinusoidal models of hepatic drug elimination in the isolated perfused rat liver by perturbation of propranolol protein binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lactosylation of albumin reduces uptake rate of dibromosulfophthalein in perfused rat liver and dissociation rate from albumin in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of hypoxia on the disposition of propranolol and sodium taurocholate by the isolated perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic transport kinetics and plasma disappearance curves: distributed modeling versus conventional approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between in-vitro microsomal enzyme activity and whole organ hepatic elimination kinetics: analysis with a dispersion model

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dispersion model of hepatic elimination: 2. Steady-state considerations-influence of hepatic blood flow, binding within blood, and hepatocellular enzyme activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of an albumin receptor in hepatic organic anion uptake: the controversy continues

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor for Albumin on the Liver Cell Surface May Mediate Uptake of Fatty Acids and Other Albumin-Bound Substances

1 reference

https://pubmed.ncbi.nlm.nih.gov/2116519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF01062200

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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