(Q38363015)

2 September 2017

E2F activity is essential for survival of Myc-overexpressing human cancer cells (English)

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2 September 2017

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7

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2 September 2017

1

Eric Santoni-Rugiu

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Jiří Bártek

6

object named as

Jiri Bartek

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2 September 2017

Eric Santoni-Rugiu

1

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2 September 2017

Dominique Duro

2

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2 September 2017

Thomas Farkas

3

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2 September 2017

Ida S Mathiasen

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2 September 2017

Marja Jäättelä

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2 September 2017

language of work or name

English

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publication date

1 September 2002

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2 September 2017

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2 September 2017

21

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2 September 2017

6498-6509

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2 September 2017

42

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205828

2 September 2017

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cites work

The retinoblastoma protein pathway and the restriction point

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Repression of c-Myc responsive genes in cycling cells causes G1 arrest through reduction of cyclin E/CDK2 kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Tissue-specific inactivation of p53 tumor suppression in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

p53 oncogene mutations in three human prostate cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

E-cadherin mediates aggregation-dependent survival of prostate and mammary epithelial cells through the retinoblastoma cell cycle control pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

The human protein p19ARF is not detected in hemopoietic human cell lines that abundantly express the alternative beta transcript of the p16INK4a/MTS1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

p53 functions as a cell cycle control protein in osteosarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

p53 gene mutation and ink4a-arf deletion appear to be two mutually exclusive events in human glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Caspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Involvement of CPP32/Caspase-3 in c-Myc-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

The retinoblastoma protein binds to a family of E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

c-Myc overexpression uncouples DNA replication from mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Apoptotic and growth-promoting activity of E2F modulated by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Amplification, rearrangement, and elevated expression of c-myc in the human prostatic carcinoma cell line LNCaP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

MYC oncogenes and human neoplastic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

The Rb/E2F pathway and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Apoptosis and cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

INK4a/ARF locus alterations in human non-Hodgkin's lymphomas mainly occur in tumors with wild-type p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Mechanisms of apoptosis by c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

The INK4 family of cell cycle inhibitors in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Double minutes arise from circular extrachromosomal DNA intermediates which integrate into chromosomal sites in human HL-60 leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

p53-independent functions of the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Interaction between the retinoblastoma protein and the oncoprotein MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Retinoblastoma protein-dependent growth signal conflict and caspase activity are required for protein kinase C-signaled apoptosis of prostate epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

Effects of sex steroids on cell growth and C-myc oncogene expression in LN-CaP and DU-145 prostatic carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Sensitivity to myc-induced apoptosis is retained in spontaneous and transplanted lymphomas of CD2-mycER mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Activation of protein kinase C induces nuclear translocation of RFX1 and down-regulates c-myc via an intron 1 X box in undifferentiated leukemia HL-60 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Cell anchorage regulates apoptosis through the retinoblastoma tumor suppressor/E2F pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

The proto-oncogene c-myc and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

RB regulates the stability and the apoptotic function of p53 via MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Myc requires distinct E2F activities to induce S phase and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Chimeric amplicons containing the c-myc gene in HL60 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

The E2F transcription factors: key regulators of cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205828

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205828

1 reference

Dimensions Publication ID

2 September 2017

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1 reference