(Q38402247)

2 September 2017

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title

Cellular stress responses in hepatitis C virus infection: Mastering a two-edged sword (English)

1 reference

2 September 2017

1 reference

1 reference

Pablo Gastaminza Landart

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25836277%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Claudia Vasallo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25836277%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

30 March 2015

1 reference

2 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25836277%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

209

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25836277%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

100-117

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25836277%20AND%20SRC:MED&resulttype=core&format=json

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Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence

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Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy

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In situ detection of oxidative DNA damage, 8-hydroxydeoxyguanosine, in chronic human liver disease

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Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes

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Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production

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Hepatitis C virus NS5A protein enhances gluconeogenesis through upregulation of Akt-/JNK-PEPCK signalling pathways

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Aggrephagy: selective disposal of protein aggregates by macroautophagy.

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Visualizing hepatitis C virus infections in human liver by two-photon microscopy

7 January 2021

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Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD

7 January 2021

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Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production

7 January 2021

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The ins and outs of hepatitis C virus entry and assembly

7 January 2021

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Critical Role of Cyclophilin A and Its Prolyl-Peptidyl Isomerase Activity in the Structure and Function of the Hepatitis C Virus Replication Complex

7 January 2021

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Hepatitis C Virus Triggers Mitochondrial Permeability Transition with Production of Reactive Oxygen Species, Leading to DNA Damage and STAT3 Activation

7 January 2021

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Endoplasmic reticulum stress in liver disease

7 January 2021

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Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

7 January 2021

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Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication

7 January 2021

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Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

7 January 2021

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σ-1 receptor at the mitochondrial-associated endoplasmic reticulum membrane is responsible for mitochondrial metabolic regulation

7 January 2021

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Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

7 January 2021

1 reference

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Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF.

7 January 2021

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Getting RIDD of RNA: IRE1 in cell fate regulation

7 January 2021

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Lack of sigma-1 receptor exacerbates ALS progression in mice

7 January 2021

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Signal transducer and activator of transcription 3 is a proviral host factor for hepatitis C virus.

7 January 2021

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No evidence of the unfolded protein response in patients with chronic hepatitis C virus infection

7 January 2021

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HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response

7 January 2021

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Sigma-1 receptors regulate Bcl-2 expression by reactive oxygen species-dependent transcriptional regulation of nuclear factor kappaB

7 January 2021

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Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants

7 January 2021

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Function of sigma1 receptors in Parkinson's disease

7 January 2021

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Low density of sigma1 receptors in early Alzheimer's disease

7 January 2021

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Sigma-1Rs are upregulated via PERK/eIF2α/ATF4 pathway and execute protective function in ER stress.

7 January 2021

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The lipid droplet is an important organelle for hepatitis C virus production

7 January 2021

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The role of the Atg1/ULK1 complex in autophagy regulation

7 January 2021

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Autophagy: renovation of cells and tissues

7 January 2021

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Hepatitis C virus-induced autophagy is independent of the unfolded protein response

7 January 2021

1 reference

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Sigma-1 receptor chaperone at the ER-mitochondrion interface mediates the mitochondrion-ER-nucleus signaling for cellular survival

7 January 2021

1 reference

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Compromising σ-1 receptors at the endoplasmic reticulum render cytotoxicity to physiologically relevant concentrations of dopamine in a nuclear factor-κB/Bcl-2-dependent mechanism: potential relevance to Parkinson's disease

7 January 2021

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The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice

7 January 2021

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Nrf2-Keap1 defines a physiologically important stress response mechanism

7 January 2021

1 reference

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Hepatitis C virus nonstructural proteins are localized in a modified endoplasmic reticulum of cells expressing viral subgenomic replicons

7 January 2021

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Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice

7 January 2021

1 reference

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Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1 and Stimulates the Synthesis of Vascular Endothelial Growth Factor

7 January 2021

1 reference

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Abnormalities of lipid metabolism in hepatitis C virus infection

7 January 2021

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Hepatitis C virus, steatosis and lipid abnormalities: clinical and pathogenic data

7 January 2021

1 reference

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Hepatitis C virus-induced cytoplasmic organelles use the nuclear transport machinery to establish an environment conducive to virus replication

7 January 2021

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Stearoyl coenzyme A desaturase 1 is associated with hepatitis C virus replication complex and regulates viral replication

7 January 2021

1 reference

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Autophagy is activated for cell survival after endoplasmic reticulum stress

7 January 2021

1 reference

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Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

7 January 2021

1 reference

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A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication

7 January 2021

1 reference

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Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein

7 January 2021

1 reference

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Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins

7 January 2021

1 reference

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Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents

7 January 2021

1 reference

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Modulation of hepatitis C virus RNA abundance and virus release by dispersion of processing bodies and enrichment of stress granules

7 January 2021

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The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements

7 January 2021

1 reference

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Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation

7 January 2021

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Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines

7 January 2021

1 reference

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Hepatitis viruses and the MAPK pathway: is this a survival strategy?

7 January 2021

1 reference

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Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease

7 January 2021

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The heat shock cognate protein 70 is associated with hepatitis C virus particles and modulates virus infectivity

7 January 2021

1 reference

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1Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with tumor necrosis factor receptor-associated factor 2.

7 January 2021

1 reference

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Hepatitis C virus nonstructural protein 5A favors upregulation of gluconeogenic and lipogenic gene expression leading towards insulin resistance: a metabolic syndrome

7 January 2021

1 reference

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Mitophagy and mitochondrial balance

7 January 2021

1 reference

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Dengue virus modulates the unfolded protein response in a time-dependent manner

7 January 2021

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HCV infection induces mitochondrial bioenergetic unbalance: causes and effects

7 January 2021

1 reference

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Hepatitis C virus protein expression causes calcium-mediated mitochondrial bioenergetic dysfunction and nitro-oxidative stress

7 January 2021

1 reference

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Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis

7 January 2021

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Targeting mitochondria in the infection strategy of the hepatitis C virus

7 January 2021

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Stress-responsive regulation of mitochondria through the ER unfolded protein response.

7 January 2021

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A small-molecule probe for hepatitis C virus replication that blocks protein folding.

7 January 2021

1 reference

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The sigma1 receptor interacts with N-alkyl amines and endogenous sphingolipids.

7 January 2021

1 reference

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Activity of hexokinase is increased by its interaction with hepatitis C virus protein NS5A.

7 January 2021

1 reference

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Changes in autophagic response in patients with chronic hepatitis C virus infection

7 January 2021

1 reference

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How positive-strand RNA viruses benefit from autophagosome maturation

7 January 2021

1 reference

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Hepatitis C Virus-Linked Mitochondrial Dysfunction Promotes Hypoxia-Inducible Factor 1 -Mediated Glycolytic Adaptation

7 January 2021

1 reference

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Metabolomic profile of hepatitis C virus-infected hepatocytes

7 January 2021

1 reference

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Hepatitis C virus infection alters lipid metabolism depending on IL28B polymorphism and viral genotype and modulates gene expression in vivo and in vitro.

7 January 2021

1 reference

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Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication

7 January 2021

1 reference

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

7 January 2021

1 reference

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Interplay between Hepatitis C Virus and Redox Cell Signaling

7 January 2021

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Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection

7 January 2021

1 reference

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Hepatitis C virus, mitochondria and auto/mitophagy: exploiting a host defense mechanism

7 January 2021

1 reference

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Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

7 January 2021

1 reference

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Role of the endoplasmic reticulum-associated degradation (ERAD) pathway in degradation of hepatitis C virus envelope proteins and production of virus particles

7 January 2021

1 reference

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ER stress-induced cell death mechanisms

7 January 2021

1 reference

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Impaired mitochondrial β-oxidation in patients with chronic hepatitis C: relation with viral load and insulin resistance

7 January 2021

1 reference

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HCV and host lipids: an intimate connection

7 January 2021

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Understanding the hepatitis C virus life cycle paves the way for highly effective therapies.

7 January 2021

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Endoplasmic reticulum stress responses

7 January 2021

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Targeting of hepatitis C virus core protein to mitochondria through a novel C-terminal localization motif

7 January 2021

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Global epidemiology of hepatitis C virus infection

7 January 2021

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Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagy

7 January 2021

1 reference

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Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling.

7 January 2021

1 reference

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Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes

7 January 2021

1 reference

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Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

7 January 2021

1 reference

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Modulation of the autophagy pathway by human tumor viruses

7 January 2021

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Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

7 January 2021

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Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

7 January 2021

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Replication of hepatitis C virus RNA on autophagosomal membranes

7 January 2021

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Perturbation of autophagic pathway by hepatitis C virus

7 January 2021

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XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

7 January 2021

1 reference

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The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade

7 January 2021

1 reference

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Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.

7 January 2021

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Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus

7 January 2021

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AAG8 promotes carcinogenesis by activating STAT3.

7 January 2021

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Hepatitis C virus hijacks host lipid metabolism

7 January 2021

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Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus

7 January 2021

1 reference

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Cochaperone Activity of Human Butyrate-Induced Transcript 1 Facilitates Hepatitis C Virus Replication through an Hsp90-Dependent Pathway

7 January 2021

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Sigma-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells: potential relation to lipid raft reconstitution

7 January 2021

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Autophagic control of RLR signaling

7 January 2021

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Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles

7 January 2021

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Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response

7 January 2021

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Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway

7 January 2021

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Hepatitis C virus, ER stress, and oxidative stress

7 January 2021

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Mitochondrial lipid trafficking

7 January 2021

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Mitochondrial quality control by the ubiquitin-proteasome system

7 January 2021

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Insights into the Sigma-1 receptor chaperone's cellular functions: a microarray report

7 January 2021

1 reference

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Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein

7 January 2021

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Oxidative protein folding in eukaryotes: mechanisms and consequences

7 January 2021

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The interplay between mitochondrial dynamics and mitophagy

7 January 2021

1 reference

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Heat-shock Protein 90 Is Essential for Stabilization of the Hepatitis C Virus Nonstructural Protein NS3

7 January 2021

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MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond

7 January 2021

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A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum.

7 January 2021

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Low oxygen tension enhances hepatitis C virus replication.

7 January 2021

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Oxidative stress in symptom-free HCV carriers: relation with ALT flare-up.

7 January 2021

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Autophagy protects cells from HCV-induced defects in lipid metabolism

7 January 2021

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Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances

7 January 2021

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Hepatitis C virus NS2 protein triggers endoplasmic reticulum stress and suppresses its own viral replication

7 January 2021

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The unfolded protein response: from stress pathway to homeostatic regulation

7 January 2021

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Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes

7 January 2021

1 reference

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Hepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression

7 January 2021

1 reference

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Role of Hepatitis C virus core protein in viral-induced mitochondrial dysfunction

7 January 2021

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Interactions Between Hepatitis C Virus and Mitochondria: Impact on Pathogenesis and Innate Immunity

7 January 2021

1 reference

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Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress

7 January 2021

1 reference

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Hepatitis C Virus Stimulates the Expression of Cyclooxygenase-2 via Oxidative Stress: Role of Prostaglandin E2 in RNA Replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Endoplasmic reticulum (ER) stress: hepatitis C virus induces an ER-nucleus signal transduction pathway and activates NF-kappaB and STAT-3.

7 January 2021

1 reference

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Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

7 January 2021

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JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

7 January 2021

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The emerging role of ROS-generating NADPH oxidase NOX4 in DNA-damage responses

7 January 2021

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The double-edged sword of autophagy modulation in cancer

7 January 2021

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Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver

7 January 2021

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A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Endoplasmic reticulum stress links hepatitis C virus RNA replication to wild-type PGC-1α/liver-specific PGC-1α upregulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Hepatitis C virus co-opts Ras-GTPase-activating protein-binding protein 1 for its genome replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

A time-dependent phase shift in the mammalian unfolded protein response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

PKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

COX5B regulates MAVS-mediated antiviral signaling through interaction with ATG5 and repressing ROS production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Biliverdin inhibits hepatitis C virus nonstructural 3/4A protease activity: mechanism for the antiviral effects of heme oxygenase?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013

Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2015.03.013