(Q38418286)

PubMed publication ID

2 September 2017

3 references

31 July 2020

23 November 2020

Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

1 reference

31 July 2020

1 reference

23 November 2020

heparan sulfate proteoglycans

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

3

Chiara Urbinati

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

2

Antonella Bugatti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

1

Paola Chiodelli

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

10 April 2015

3 references

PubMed publication ID

2 September 2017

31 July 2020

23 November 2020

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

31 July 2020

23 November 2020

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

page(s)

6342-6388

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

Creative Commons Attribution

13 May 2020

copyright license

2 references

31 July 2020

23 November 2020

0 references

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Angiogenesis in cancer, vascular, rheumatoid and other disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Integrin function in vascular biology: a view from 2013.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Vascular endothelial-cadherin and vascular stability

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Extracellular angiogenic growth factor interactions: an angiogenesis interactome survey

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Role of uPA/uPAR in the modulation of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1: possible involvement of c-Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Vascular endothelial growth factor A (VEGF-A) induces endothelial and cancer cell migration through direct binding to integrin {alpha}9{beta}1: identification of a specific {alpha}9{beta}1 binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Isoforms of receptors of fibroblast growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Cellular signaling by fibroblast growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

alphavbeta3 integrin mediates the cell-adhesive capacity and biological activity of basic fibroblast growth factor (FGF-2) in cultured endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The impact of heparanese and heparin on cancer metastasis and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Activated blood coagulation factor X (FXa) induces angiogenic growth factor expression in human retinal pigment epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Induction of endothelial cell proliferation by angiogenic factors released by activated monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interleukin-8 differentially regulates migration of tumor-associated and normal human brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Basic fibroblast growth factor (bFGF) regulates the expression of the CC chemokine monocyte chemoattractant protein-1 (MCP-1) in autocrine-activated endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Viruses as key regulators of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Significance of heparin-binding growth factor expression on cells of solid pediatric tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Inhibition of angiogenesis and the angiogenesis/invasion shift

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Demystifying heparan sulfate-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Pathophysiology of heparan sulphate: many diseases, few drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Molecular diversity of heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Endothelial cells interact with the core protein of basement membrane perlecan through beta 1 and beta 3 integrins: an adhesion modulated by glycosaminoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interaction of angiogenic basic fibroblast growth factor with endothelial cell heparan sulfate proteoglycans. Biological implications in neovascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Anticoagulant heparan sulfate: structural specificity and biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

21 January 2018

The lipase gene family

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Antithrombin: in control of coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Biotechnological engineering of heparin/heparan sulphate: a novel area of multi-target drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The heparin-binding site of antithrombin is crucial for antiangiogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interactions between heparan sulfate and proteins: the concept of specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The heparin-binding protein interactome in pancreatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Angiopoietin-3 is tethered on the cell surface via heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

A heparin-binding form of placenta growth factor (PlGF-2) is expressed in human umbilical vein endothelial cells and in placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterization of heparin and heparan sulfate domains binding to the long splice variant of platelet-derived growth factor A chain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Glycosaminoglycan structures required for strong binding to midkine, a heparin-binding growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

HB-EGF function in cardiac valve development requires interaction with heparan sulfate proteoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparan sulfate proteoglycans mediate the angiogenic activity of the vascular endothelial growth factor receptor-2 agonist gremlin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin/heparan sulphate binding in the TGF-beta cytokine superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

WSS25 Inhibits Growth of Xenografted Hepatocellular Cancer Cells in Nude Mice by Disrupting Angiogenesis via Blocking Bone Morphogenetic Protein (BMP)/Smad/Id1 Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin inhibits interferon-γ signaling in human endometrial stromal cells by interference with the cellular binding of interferon-γ.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Quantitative investigation of the interaction between granulocyte-macrophage colony-stimulating factor and heparin by capillary zone electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterization of the interaction of interleukin-8 with hyaluronan, chondroitin sulfate, dermatan sulfate and their sulfated derivatives by spectroscopy and molecular modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Differentiation of 3-O-sulfated heparin disaccharide isomers: identification of structural aspects of the heparin CCL2 binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

RANTES/CCL5-induced pro-angiogenic effects depend on CCR1, CCR5 and glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin disrupts the CXCR4/SDF-1 axis and impairs the functional capacity of bone marrow-derived mononuclear cells used for cardiovascular repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Molecular interaction studies of HIV-1 matrix protein p17 and heparin: identification of the heparin-binding motif of p17 as a target for the development of multitarget antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Pregnancy-specific glycoprotein 1 induces endothelial tubulogenesis through interaction with cell surface proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparan sulfate regulates the antiangiogenic activity of endothelial monocyte-activating polypeptide-II at acidic pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Mechanistic study of the proangiogenic effect of osteoprotegerin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Fibrinogen and fibrin structure and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin cofactor II, a serine protease inhibitor, promotes angiogenesis via activation of the AMP-activated protein kinase-endothelial nitric-oxide synthase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Binding of heparin/heparan sulfate to fibroblast growth factor receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Molecular interplay between endostatin, integrins, and heparan sulfate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Mapping of heparin/heparan sulfate binding sites on αvβ3 integrin by molecular docking

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparan sulfate modification of the transmembrane receptor CD47 is necessary for inhibition of T cell receptor signaling by thrombospondin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterisation of the conformational changes in platelet factor 4 induced by polyanions: towards in vitro prediction of antigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Histidine-Rich Glycoprotein and Platelet Factor 4 Mask Heparan Sulfate Proteoglycans Recognized by Acidic and Basic Fibroblast Growth Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin displaces interferon-gamma-inducible chemokines (IP-10, I-TAC, and Mig) sequestered in the vasculature and inhibits the transendothelial migration and arterial recruitment of T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Pigment epithelium-derived factor (PEDF) shares binding sites in collagen with heparin/heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfated glycosaminoglycans control the extracellular trafficking and the activity of the metalloprotease inhibitor TIMP-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Laminin alpha5 chain metastasis- and angiogenesis-inhibiting peptide blocks fibroblast growth factor 2 activity by binding to the heparan sulfate chains of CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

In vitro and in vivo antiangiogenic properties of the serpin protease nexin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterization of the human sulfatase Sulf1 and its high affinity heparin/heparan sulfate interaction domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Binding of the NG2 proteoglycan to kringle domains modulates the functional properties of angiostatin and plasmin(ogen).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Multiple mechanisms for exogenous heparin modulation of vascular endothelial growth factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

A surface plasmon resonance-based solution affinity assay for heparan sulfate-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Variations in the Size and Sulfation of Heparin Modulate the Effect of Heparin on the Binding of VEGF165 to Its Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Structural features in heparin that interact with VEGF165 and modulate its biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The interaction of the transforming growth factor-betas with heparin/heparan sulfate is isoform-specific.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Structural requirements of heparan sulfate for the binding to the tumor-derived adhesion factor/angiomodulin that induces cord-like structures to ECV-304 human carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The basic domain in HIV-1 Tat protein as a target for polysulfonated heparin-mimicking extracellular Tat antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Defining the interleukin-8-binding domain of heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterization of the stromal cell-derived factor-1alpha-heparin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Effects of sulfate position on heparin octasaccharide binding to CCL2 examined by tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Profiling heparin-chemokine interactions using synthetic tools

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Distinct role of 2-O-, N-, and 6-O-sulfate groups of heparin in the formation of the ternary complex with basic fibroblast growth factor and soluble FGF receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interaction of thrombospondin-1 and heparan sulfate from endothelial cells. Structural requirements of heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Role of heparan sulfate domain organization in endostatin inhibition of endothelial cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Binding of endostatin to endothelial heparan sulphate shows a differential requirement for specific sulphates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Molecular docking of heparin oligosaccharides with Hep-II heparin-binding domain of fibronectin reveals an interplay between the different positions of sulfate groups

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Three-dimensional structure of human basic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Fibroblast growth factor-specific modulation of cellular response by syndecan-4

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Internalization of basic fibroblast growth factor (bFGF) in cultured endothelial cells: role of the low affinity heparin-like bFGF receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interaction of heparin with human basic fibroblast growth factor: protection of the angiogenic protein from proteolytic degradation by a glycosaminoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Short heparin sequences spaced by glycol-split uronate residues are antagonists of fibroblast growth factor 2 and angiogenesis inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

A dual receptor system is required for basic fibroblast growth factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Different effects of mucosal, bovine lung and chemically modified heparin on selected biological properties of basic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Basic fibroblast growth factor: lysine 134 is essential for its neuroprotective activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Solution structure of midkine, a new heparin-binding growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Identification and dynamics of a heparin-binding site in hepatocyte growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The N-terminal domain of hepatocyte growth factor inhibits the angiogenic behavior of endothelial cells independently from binding to the c-met receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Effect of HGF-like basic hexapeptides on angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Investigation of lysine side chain interactions of interleukin-8 with heparin and other glycosaminoglycans studied by a methylation-NMR approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interferon-gamma binds to heparan sulfate by a cluster of amino acids located in the C-terminal part of the molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Transforming growth factor-beta 1 is a heparin-binding protein: identification of putative heparin-binding regions and isolation of heparins with varying affinity for TGF-beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin-binding sites in granulocyte-macrophage colony-stimulating factor. Localization and regulation by histidine ionization.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Lysine 58 and histidine 66 at the C-terminal alpha-helix of monocyte chemoattractant protein-1 are essential for glycosaminoglycan binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

A molecular mechanism for the heparan sulfate dependence of slit-robo signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparan sulfates mediate the binding of basic fibroblast growth factor to a specific receptor on neural precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Identification of heparin-binding sites in proteins by selective labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Endostatin phenylalanines 31 and 34 define a receptor binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Structure of murine angiogenin: features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Nuclear translocation of angiogenin in proliferating endothelial cells is essential to its angiogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Limited proteolysis by chymotrypsin of midkine and inhibition by heparin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Chondroitin sulfate chains on syndecan-1 and syndecan-4 from normal murine mammary gland epithelial cells are structurally and functionally distinct and cooperate with heparan sulfate chains to bind growth factors. A novel function to control bindin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

HGF/c-MET targeted therapeutics: novel strategies for cancer medicine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Dissociation of heparan sulfate and receptor binding domains of hepatocyte growth factor reveals that heparan sulfate-c-met interaction facilitates signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterization of heparan sulfate oligosaccharides that bind to hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin-mediated selective release of hepatocyte growth factor in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfated oligosaccharides promote hepatocyte growth factor association and govern its mitogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Substrate-immobilized HIV-1 Tat drives VEGFR2/α(v)β(3)-integrin complex formation and polarization in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

BSA conjugates bearing multiple copies of the basic domain of HIV-1 Tat: Prototype for the development of multitarget inhibitors of extracellular Tat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Pentosan polysulfate as an inhibitor of extracellular HIV-1 Tat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Identification of specific molecular structures of human immunodeficiency virus type 1 Tat relevant for its biological effects on vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Differential binding of platelet-derived growth factor isoforms to glycosaminoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Compartmentalization of PDGF on extracellular binding sites dependent on exon-6-encoded sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin amplifies platelet-derived growth factor (PDGF)- BB-induced PDGF alpha -receptor but not PDGF beta -receptor tyrosine phosphorylation in heparan sulfate-deficient cells. Effects on signal transduction and biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Transforming growth factor β family members in regulation of vascular function: in the light of vascular conditional knockouts

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Monocyte chemotactic protein (MCP)-1 promotes angiogenesis via a novel transcription factor, MCP-1-induced protein (MCPIP)

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Chemokine-glycosaminoglycan binding: specificity for CCR2 ligand binding to highly sulfated oligosaccharides using FTICR mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Collagen XVIII, a basement membrane heparan sulfate proteoglycan, interacts with L-selectin and monocyte chemoattractant protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin decreases the blood clearance of interferon-gamma and increases its activity by limiting the processing of its carboxyl-terminal sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Examination of the mechanism by which heparin antagonizes activation of a model endothelium by interferon-gamma (IFN-gamma).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

HIV-1 p17 matrix protein interacts with heparan sulfate side chain of CD44v3, syndecan-2, and syndecan-4 proteoglycans expressed on human activated CD4+ T cells affecting tumor necrosis factor alpha and interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Acidic pH modulates the interaction between human granulocyte-macrophage colony-stimulating factor and glycosaminoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

On the binding of tumor necrosis factor (TNF) to heparin and the release in vivo of the TNF-binding protein I by heparin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Tumour necrosis factor-alpha interacts with biglycan and decorin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The fourth immunoglobulin-like loop in the extracellular domain of FLT-1, a VEGF receptor, includes a major heparin-binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The morphogenic properties of oligomeric endostatin are dependent on cell surface heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The chemokine system -- a major regulator of angiogenesis in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Different affinities of glycosaminoglycan oligosaccharides for monomeric and dimeric interleukin-8: a model for chemokine regulation at inflammatory sites

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

A chemokine self-presentation mechanism involving formation of endothelial surface microstructures

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interleukin-8 binds to syndecan-2 on human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Noncompetitive, chemokine-mediated inhibition of basic fibroblast growth factor-induced endothelial cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Cell adhesion and signaling on the fibronectin 1st type III repeat; requisite roles for cell surface proteoglycans and integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Zn2+ mediates high affinity binding of heparin to the αC domain of fibrinogen

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin-binding epidermal growth factor-like growth factor: p91 activation induction of plasminogen activator/inhibitor, and tubular morphogenesis in human microvascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

A distinct basic fibroblast growth factor (FGF-2)/FGF receptor interaction distinguishes urokinase-type plasminogen activator induction from mitogenicity in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

A fragment of histidine-rich glycoprotein is a potent inhibitor of tumor vascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The anti-angiogenic His/Pro-rich fragment of histidine-rich glycoprotein binds to endothelial cell heparan sulfate in a Zn2+-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interaction of platelet factor 4 with fibroblast growth factor 2 is stabilised by heparan sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The repertoire of glycan determinants in the human glycome

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Therapeutically targeting protein-glycan interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

HSPG-binding peptide corresponding to the exon 6a-encoded domain of VEGF inhibits tumor growth by blocking angiogenesis in murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Inhibition of the mitogenic, angiogenic and tumorigenic activities of pleiotrophin by a synthetic peptide corresponding to its C-thrombospondin repeat-I domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Bovine lactoferricin inhibits basic fibroblast growth factor- and vascular endothelial growth factor165-induced angiogenesis by competing for heparin-like binding sites on endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Recombinant platelet factor 4: a therapeutic, anti-neoplastic chimera?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Inhibition of tumor cell migration by LD22-4, an N-terminal fragment of 24-kDa FGF2, is mediated by Neuropilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Bioactivity screening of partially desulfated low-molecular-weight heparins: a structure/activity relationship study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Binding affinities of vascular endothelial growth factor (VEGF) for heparin-derived oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Antiangiogenic and anticancer effect of an orally active low molecular weight heparin conjugates and its application to lung cancer chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

LHT7, a chemically modified heparin, inhibits multiple stages of angiogenesis by blocking VEGF, FGF2 and PDGF-B signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Undersulfated, low-molecular-weight glycol-split heparin as an antiangiogenic VEGF antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

A small oxazine compound as an anti-tumor agent: a novel pyranoside mimetic that binds to VEGF, HB-EGF, and TNF-α.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Vascular endothelial growth factor 165 (VEGF(165)) activities are inhibited by carboxymethyl benzylamide dextran that competes for heparin binding to VEGF(165) and VEGF(165).KDR Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Synthesis of a heparan sulfate mimetic library targeting FGF and VEGF via click chemistry on a monosaccharide template

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Undersulfated and glycol-split heparins endowed with antiangiogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Anti-proliferative effects of O-acyl-low-molecular-weight heparin derivatives on bovine pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfated malto-oligosaccharides bind to basic FGF, inhibit endothelial cell proliferation, and disrupt endothelial cell tube formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Inhibition by Pentosan Polysulfate (PPS) of Heparin-Binding Growth Factors Released From Tumor Cells and Blockage by PPS of Tumor Growth in Animals

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Enzymatic redesigning of biologically active heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Studies of marine sulfated polymannuroguluronate on endothelial cell proliferation and endothelial immunity and related mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Application of the four-component Ugi condensation for the preparation of sulfated glycoconjugate libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

An experimental and molecular-modeling study of the binding of linked sulfated tetracyclitols to FGF-1 and FGF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Chemically sulfated Escherichia coli K5 polysaccharide derivatives as extracellular HIV-1 Tat protein antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interaction of the transactivating protein HIV-1 tat with sulphated polysaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfated polymannuroguluronate, a novel anti-AIDS drug candidate, inhibits HIV-1 Tat-induced angiogenesis in Kaposi's sarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Fucoidan modulates the effect of transforming growth factor (TGF)-beta1 on fibroblast proliferation and wound repopulation in in vitro models of dermal wound repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Synthesis of tailor-made glycoconjugate mimetics of heparan sulfate that bind IFN-gamma in the nanomolar range

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Inhibition of heparanase activity and heparanase-induced angiogenesis by suramin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Discovery of novel sulfonated small molecules that inhibit vascular tube formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Polysulfated/sulfonated compounds for the development of drugs at the crossroad of viral infection and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Polyanionic drugs and viral oncogenesis: a novel approach to control infection, tumor-associated inflammation and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Emerging sulfated flavonoids and other polyphenols as drugs: nature as an inspiration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin-mimicking sulfonic acid polymers as multitarget inhibitors of human immunodeficiency virus type 1 Tat and gp120 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Compositional analysis of heparin/heparan sulfate interacting with fibroblast growth factor.fibroblast growth factor receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

The marine-derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Suppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Interfering with UDP-GlcNAc metabolism and heparan sulfate expression using a sugar analogue reduces angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Novel glycosaminoglycan biosynthetic inhibitors affect tumor-associated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin regulates vascular endothelial growth factor165-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells. Comparison of the effects of heparin and modified heparins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfate moieties in the subendothelial extracellular matrix are involved in basic fibroblast growth factor sequestration, dimerization, and stimulation of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparan sulfate proteoglycans function as receptors for fibroblast growth factor-2 activation of extracellular signal-regulated kinases 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparinase inhibits neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Cell surface biology mediated by low affinity multivalent protein-glycan interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Raman spectroscopic investigation of peptide-glycosaminoglycan interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Conformational requirements of suramin to target angiogenic growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Chemoenzymatic synthesis of glycosaminoglycans: re-creating, re-modeling and re-designing nature's longest or most complex carbohydrate chains

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Toward the solid-phase synthesis of heparan sulfate oligosaccharides: evaluation of iduronic acid and idose building blocks

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Use of sulfated linked cyclitols as heparan sulfate mimetics to probe the heparin/heparan sulfate binding specificity of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Characterization of the effects of two polysulfonated distamycin A derivatives, PNU145156E and PNU153429, on HIV type 1 Tat protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Finding a needle in a haystack: development of a combinatorial virtual screening approach for identifying high specificity heparin/heparan sulfate sequence(s).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Identification of inhibitors of heparin-growth factor interactions from combinatorial libraries of four-component condensation reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Cyclic RGDyk-conjugated LMWH-taurocholate derivative as a targeting angiogenesis inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfated K5 Escherichia coli polysaccharide derivatives: A novel class of candidate antiviral microbicides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Sulfated Derivatives of Escherichia coli K5 Polysaccharides as Modulators of Fibroblast Growth Factor Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Modulatory effects of Escherichia coli capsular-derived sulfaminoheparosans and heparins on tissue factor-mediated activation of platelets: flow cytometric analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Semi-synthetic heparinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Glycosaminoglycans Mediate Cell Surface Oligomerization of Chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Heparin-integrin interaction in endothelial cells: Downstream signaling and heparan sulfate expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Fibroblast Growth Factor Receptors 1 and 2 Interact Differently with Heparin/Heparan Sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Protamine is an inhibitor of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Suramin is a Potent Inhibitor of Vascular Endothelial Growth Factor. A Contribution to the Molecular Basis of its Antiangiogenic Action

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20046342

Angiogenic response of endothelial cells to heparin-binding domain of fibronectin

21 January 2018

1 reference

12 December 2020

Selective inhibition of cell proliferation and DNA synthesis by the polysulphated carbohydrate l-carrageenan

1 reference

12 December 2020

Antiangiogenic activity of semisynthetic biotechnological heparins: low-molecular-weight-sulfated Escherichia coli K5 polysaccharide derivatives as fibroblast growth factor antagonists

1 reference

12 December 2020

Endostatin competes with bFGF for binding to heparin-like glycosaminoglycans

1 reference

12 December 2020

Platelet factor 4 gene transfection into tumor cells inhibits angiogenesis, tumor growth and metastasis.

1 reference

12 December 2020

In vivo angiogenic activity of urokinase: role of endogenous fibroblast growth factor-2.

1 reference

12 December 2020

Characterization of sequences within heparin-binding EGF-like growth factor that mediate interaction with heparin

1 reference

12 December 2020

The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules

1 reference

12 December 2020

Interaction of plasminogen activators and plasminogen with heparin: effect of ionic strength

1 reference

12 December 2020

Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells

1 reference

12 December 2020

The heparin-binding domain confers diverse functions of VEGF-A in development and disease: a structure-function study

1 reference

12 December 2020

Sulfated beta-(1-->4)-galacto-oligosaccharides and their effect on angiogenesis

1 reference

12 December 2020

Structural characteristics of heparin-line domain required for interaction of midkine with embryonic neurons

1 reference

12 December 2020

Fibroblast growth factor-2 antagonist activity and angiostatic capacity of sulfated Escherichia coli K5 polysaccharide derivatives

1 reference

12 December 2020

Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors.

1 reference

12 December 2020

Antiangiogenic antithrombin blocks the heparan sulfate-dependent binding of proangiogenic growth factors to their endothelial cell receptors: evidence for differential binding of antiangiogenic and anticoagulant forms of antithrombin to proangiogeni

1 reference

12 December 2020

Hepatocyte growth factor immobilized onto culture substrates through heparin and matrigel enhances DNA synthesis in primary rat hepatocytes

1 reference

12 December 2020

Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: functional analysis of the tumor necrosis factor receptors

1 reference

12 December 2020

Alginate oligosaccharides stimulate VEGF-mediated growth and migration of human endothelial cells

1 reference

12 December 2020

Interaction of heparin with human angiogenin

1 reference

12 December 2020

HIV-tat protein is a heparin-binding angiogenic growth factor

1 reference

12 December 2020

Importance of the spatial display of charged residues in heparin-peptide interactions

1 reference

12 December 2020

Inhibitory effect of platelet factor 4 on human erythroleukemic cells is dependent on cell surface heparan sulfate

1 reference

12 December 2020

Heparin protects basic and acidic FGF from inactivation

1 reference

12 December 2020

A motif within the N-terminal domain of TSP-1 specifically promotes the proangiogenic activity of endothelial colony-forming cells

1 reference

12 December 2020

Synthesis and biological evaluation of 2-amino-2-deoxy- and 6-amino-6-deoxy-cyclomaltoheptaose polysulfates as synergists for angiogenesis inhibition

1 reference

12 December 2020

Platelet factor-4 inhibits the mitogenic activity of VEGF121 and VEGF165 using several concurrent mechanisms

1 reference

12 December 2020

Modulation of fibroblast growth factor-2 receptor binding, signaling, and mitogenic activity by heparin-mimicking polysulfonated compounds.

1 reference

12 December 2020

Neuropilin-1 is a placenta growth factor-2 receptor

1 reference

12 December 2020

2.5 kDa and 5.0 kDa heparin fragments specifically inhibit microvessel sprouting and network formation in VEGF165-mediated mammalian angiogenesis

1 reference

12 December 2020

Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator

1 reference

12 December 2020

Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities

1 reference

12 December 2020

Distinct heparin binding sites on VEGF165 and its receptors revealed by their interaction with a non sulfated glycoaminoglycan (NaPaC)

1 reference

12 December 2020

Identification of novel heparin-releasable proteins, as well as the cytokines midkine and pleiotrophin, in human postheparin plasma.

1 reference

12 December 2020

Monocyte chemoattractant protein-1-induced angiogenesis is mediated by vascular endothelial growth factor-A

1 reference

12 December 2020

Heparinlike molecules with anticoagulant activity are synthesized by cultured endothelial cells

1 reference

12 December 2020

Heparin inhibits TNF- signaling in human endometrial stromal cells by interaction with NF- B

1 reference

12 December 2020

Selective expression and processing of biglycan during migration of bovine aortic endothelial cells. The role of endogenous basic fibroblast growth factor

1 reference

12 December 2020

A recombinant NH2-terminal heparin-binding domain of the adhesive glycoprotein, thrombospondin-1, promotes endothelial tube formation and cell survival: a possible role for syndecan-4 proteoglycan

1 reference

12 December 2020

The role of human immunodeficiency virus-I in the pathogenesis of acquired immunodeficiency syndrome-related Kaposi's sarcoma: the importance of an inflammatory and angiogenic milieu.

1 reference

12 December 2020

Phase II study of pentosan polysulfate (PPS) in patients with AIDS-related Kaposi's sarcoma

1 reference

12 December 2020

Histidine-rich glycoprotein inhibited high mobility group box 1 in complex with heparin-induced angiogenesis in matrigel plug assay

1 reference

12 December 2020

Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.

1 reference

12 December 2020

Basic fibroblast growth factor is internalized through both receptor-mediated and heparan sulfate-mediated mechanisms.

1 reference

12 December 2020

The heparan sulfate suleparoide inhibits rat corneal angiogenesis and in vitro neovascularization

1 reference

12 December 2020

Activity of pentosan polysulphate and derived compounds on vascular endothelial cell proliferation and migration induced by acidic and basic FGF in vitro

1 reference

12 December 2020

Protection of transforming growth factor-beta 1 activity by heparin and fucoidan

1 reference

12 December 2020

In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF.

1 reference

12 December 2020

Identification of cell-binding site of angiomodulin (AGM/TAF/Mac25) that interacts with heparan sulfates on cell surface

1 reference

12 December 2020

Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate

1 reference

12 December 2020

Tumour necrosis factor and cancer

1 reference

12 December 2020

Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors

1 reference

12 December 2020

High-level expression of angiogenic factors is associated with advanced tumor stage in human neuroblastomas

1 reference

12 December 2020

Structural elements of kallistatin required for inhibition of angiogenesis

1 reference

12 December 2020

Multimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxis

1 reference

12 December 2020

Basic fibroblast growth factor is released from endothelial extracellular matrix in a biologically active form

1 reference

12 December 2020

Energetic characterization of the basic fibroblast growth factor-heparin interaction: identification of the heparin binding domain

1 reference

12 December 2020

PNU-145156E, a novel angiogenesis inhibitor, in patients with solid tumors: a phase I and pharmacokinetic study

1 reference

12 December 2020

Characterization of the binding site on heparan sulfate for macrophage inflammatory protein 1alpha

1 reference

12 December 2020

Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent

1 reference

12 December 2020

Preparation of affinity-fractionated, heparin-derived oligosaccharides and their effects on selected biological activities mediated by basic fibroblast growth factor.

1 reference

12 December 2020

The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1

1 reference

12 December 2020

The potential mechanism for the effect of heparin on tissue plasminogen activator-mediated plasminogen activation

1 reference

12 December 2020

Modulation of human endothelial cell proliferation and migration by fucoidan and heparin

1 reference

12 December 2020

Angiogenic growth factors interactome and drug discovery: The contribution of surface plasmon resonance.

1 reference

12 December 2020

Synthetic peptide F2A4-K-NS mimics fibroblast growth factor-2 in vitro and is angiogenic in vivo.

1 reference

12 December 2020

Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor

1 reference

12 December 2020

Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants

1 reference

12 December 2020

Binding of interferon-gamma to heparan sulfate is restricted to the heparin-like domains and involves carboxylic--but not N-sulfated--groups

1 reference

12 December 2020

Protein specificity of charged sequences in polyanions and heparins

1 reference

12 December 2020

HIV-1 p17 binds heparan sulfate proteoglycans to activated CD4(+) T cells

1 reference

12 December 2020

Protamine sulfate inhibits mitogenic activities of the extracellular matrix and fibroblast growth factor, but potentiates that of epidermal growth factor

1 reference

12 December 2020

10.3390/MOLECULES20046342

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json

13 May 2020

PubMed publication ID

25867824

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272510&resulttype=core&format=json