(Q38552126)

4 September 2017

1 reference

title

Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis (English)

1 reference

4 September 2017

0 references

endoplasmic reticulum

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0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Javier González-Gallego

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

José L. Mauriz

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

author name string

Raquel Ordóñez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Russel J Reiter

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

publication date

22 July 2015

1 reference

Journal of Pineal Research

4 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

page(s)

292-307

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26201382%20AND%20SRC:MED&resulttype=core&format=json

Cisternal organization of the endoplasmic reticulum during mitosis

14 June 2020

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ER stress-induced cell death mechanisms

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Endoplasmic reticulum stress triggers autophagy

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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

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Melatonin as a natural ally against oxidative stress: a physicochemical examination.

21 January 2018

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21 January 2018

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Cyclic-3-hydroxymelatonin (C3HOM), a potent antioxidant, scavenges free radicals and suppresses oxidative reactions

21 January 2018

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A review of the molecular aspects of melatonin's anti-inflammatory actions: recent insights and new perspectives.

21 January 2018

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Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus

21 January 2018

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Melatonin induces cell cycle arrest and apoptosis in hepatocarcinoma HepG2 cell line

21 January 2018

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Melatonin protects against alcoholic liver injury by attenuating oxidative stress, inflammatory response, and apoptosis.

21 January 2018

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Cytoprotective effects of melatonin against necrosis and apoptosis induced by ischemia/reperfusion injury in rat liver

21 January 2018

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Melatonin attenuates lipopolysaccharide (LPS)-induced apoptotic liver damage in D-galactosamine-sensitized mice.

21 January 2018

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Melatonin treatment reduces endoplasmic reticulum stress and modulates the unfolded protein response in rabbits with lethal fulminant hepatitis of viral origin.

21 January 2018

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Melatonin modulates the autophagic response in acute liver failure induced by the rabbit hemorrhagic disease virus.

21 January 2018

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Endoplasmic reticulum stress in health and disease

21 January 2018

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Unfolded Protein Response (UPR) is activated during normal lens development

21 January 2018

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The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development.

21 January 2018

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Molecular mechanisms regulating oxidative activity of the Ero1 family in the endoplasmic reticulum

21 January 2018

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The UPR and the anti-oxidant response: relevance to sleep and sleep loss

21 January 2018

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Lipase maturation factor 1 (lmf1) is induced by endoplasmic reticulum stress through activating transcription factor 6α (Atf6α) signaling.

21 January 2018

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ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

21 January 2018

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Fasudil protects the heart against ischemia-reperfusion injury by attenuating endoplasmic reticulum stress and modulating SERCA activity: the differential role for PI3K/Akt and JAK2/STAT3 signaling pathways

21 January 2018

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Endoplasmic reticulum Ca(2+) release through ryanodine and IP(3) receptors contributes to neuronal excitotoxicity.

21 January 2018

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Modulation of STIM1 and capacitative Ca2+ entry by the endoplasmic reticulum luminal oxidoreductase ERp57

21 January 2018

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Heat stress induces apoptosis through a Ca²⁺-mediated mitochondrial apoptotic pathway in human umbilical vein endothelial cells

21 January 2018

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Functional roles of calreticulin in cancer biology

21 January 2018

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Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response.

21 January 2018

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N-linked sugar-regulated protein folding and quality control in the ER

21 January 2018

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Protein folding assisted by chaperones

21 January 2018

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Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis

21 January 2018

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Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells

21 January 2018

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Decrease in membrane phospholipid unsaturation induces unfolded protein response

21 January 2018

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Membrane lipid saturation activates IRE1α without inducing clustering

21 January 2018

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ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload

21 January 2018

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Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

21 January 2018

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The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment

21 January 2018

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Endoplasmic reticulum stress responses

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Roles of GRP78 in physiology and cancer

21 January 2018

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

Regulatory crosstalk within the mammalian unfolded protein response

21 January 2018

1 reference

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

21 January 2018

1 reference

ER stress triggers apoptosis by activating BH3-only protein Bim

21 January 2018

1 reference

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

21 January 2018

1 reference

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

21 January 2018

1 reference

Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis

21 January 2018

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Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

21 January 2018

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Stress management at the ER: regulators of ER stress-induced apoptosis

21 January 2018

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IRE1, a double-edged sword in pre-miRNA slicing and cell death

21 January 2018

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Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

21 January 2018

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Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress

21 January 2018

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A thrombospondin-dependent pathway for a protective ER stress response

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Physiological unfolded protein response regulated by OASIS family members, transmembrane bZIP transcription factors

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A review of the mammalian unfolded protein response.

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Quality control: ER-associated degradation: protein quality control and beyond

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Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy

21 January 2018

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Melatonin as a proteasome inhibitor. Is there any clinical evidence?

21 January 2018

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Melatonin and ubiquitin: what's the connection?

21 January 2018

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A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy.

21 January 2018

1 reference

Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

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Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy

21 January 2018

1 reference

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

21 January 2018

1 reference

The switch from ER stress-induced apoptosis to autophagy via ROS-mediated JNK/p62 signals: A survival mechanism in methotrexate-resistant choriocarcinoma cells

21 January 2018

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Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis

21 January 2018

1 reference

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

21 January 2018

1 reference

Taxol-induced unfolded protein response activation in breast cancer cells exposed to hypoxia: ATF4 activation regulates autophagy and inhibits apoptosis.

21 January 2018

1 reference

Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL.

21 January 2018

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21 January 2018

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21 January 2018

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Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy

21 January 2018

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Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis

21 January 2018

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IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

21 January 2018

1 reference

ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis.

21 January 2018

1 reference

Mechanisms of cytochrome c release by proapoptotic BCL-2 family members

21 January 2018

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Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis

21 January 2018

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The critical molecular interconnections in regulating apoptosis and autophagy.

21 January 2018

1 reference

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

21 January 2018

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Melatonin and mitochondrial function

21 January 2018

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Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review

21 January 2018

1 reference

The Unfolded Protein Response, Degradation from Endoplasmic Reticulum and Cancer

21 January 2018

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

21 January 2018

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Transcriptional regulation of VEGF-A by the unfolded protein response pathway

21 January 2018

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Induction of ER stress protects gastric cancer cells against apoptosis induced by cisplatin and doxorubicin through activation of p38 MAPK.

21 January 2018

1 reference

Melatonin potentiates the anti-tumour effect of pravastatin in rat mammary gland carcinoma model.

21 January 2018

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Melatonin potentiates cisplatin-induced apoptosis and cell cycle arrest in human lung adenocarcinoma cells

21 January 2018

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Melatonin: reducing the toxicity and increasing the efficacy of drugs

21 January 2018

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Circadian and melatonin disruption by exposure to light at night drives intrinsic resistance to tamoxifen therapy in breast cancer

21 January 2018

1 reference

Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

The role of cyclooxygenases in inflammation, cancer, and development

21 January 2018

1 reference

Melatonin reverses tunicamycin-induced endoplasmic reticulum stress in human hepatocellular carcinoma cells and improves cytotoxic response to doxorubicin by increasing CHOP and decreasing survivin

21 January 2018

1 reference

Inhibiting PI3K as a therapeutic strategy against cancer

21 January 2018

1 reference

Targeting phosphoinositide 3-kinase: moving towards therapy

21 January 2018

1 reference

Dual inhibition of (V600E)BRAF and the PI3K/AKT/mTOR pathway cooperates to induce apoptosis in melanoma cells through a MEK-independent mechanism

21 January 2018

1 reference

Clinical utility and economic impact of conventional transbronchial needle aspiration of mediastinal lymphadenopathies in bronchogenic carcinoma.

21 January 2018

1 reference

Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide

21 January 2018

1 reference

Melatonin combined with endoplasmic reticulum stress induces cell death via the PI3K/Akt/mTOR pathway in B16F10 melanoma cells

21 January 2018

1 reference

Protective effect of melatonin on oxaliplatin-induced apoptosis through sustained Mcl-1 expression and anti-oxidant action in renal carcinoma Caki cells

21 January 2018

1 reference

Redox signaling loops in the unfolded protein response

21 January 2018

1 reference

Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?

21 January 2018

1 reference

ER stress and neurodegenerative diseases

21 January 2018

1 reference

Enhanced phosphatidylinositol 3-kinase (PI3K)/Akt signaling has pleiotropic targets in hippocampal neurons exposed to iron-induced oxidative stress

21 January 2018

1 reference

Role of iron in neurodegenerative disorders

21 January 2018

1 reference

Biochemical and Molecular Alterations Following Arsenic-Induced Oxidative Stress and Mitochondrial Dysfunction in Rat Brain

21 January 2018

1 reference

Arsenic induces apoptosis in rat cerebellar neurons via activation of JNK3 and p38 MAP kinases

21 January 2018

1 reference

Arsenite-induced formation of hydroxyl radical in the striatum of awake rats.

21 January 2018

1 reference

Melatonin attenuates arsenite-induced apoptosis in rat brain: involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of alpha-synuclein.

21 January 2018

1 reference

Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo

21 January 2018

1 reference

Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons

21 January 2018

1 reference

Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

21 January 2018

1 reference

Melatonin inhibits arsenite-induced peripheral neurotoxicity

21 January 2018

1 reference

Melatonin suppresses cyclosporine A-induced autophagy in rat pituitary GH3 cells

21 January 2018

1 reference

Endoplasmic Reticulum Stress Plays a Key Role in Rotenone-Induced Apoptotic Death of Neurons

21 January 2018

1 reference

Melatonin reduces endoplasmic reticulum stress and preserves sirtuin 1 expression in neuronal cells of newborn rats after hypoxia-ischemia.

21 January 2018

1 reference

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

21 January 2018

1 reference

Hydrogen sulfide inhibits formaldehyde-induced endoplasmic reticulum stress in PC12 cells by upregulation of SIRT-1.

21 January 2018

1 reference

Melatonin and bright-light treatment for rest-activity disruption in institutionalized patients with Alzheimer's disease

21 January 2018

1 reference

The contribution of endoplasmic reticulum stress to liver diseases

21 January 2018

1 reference

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

21 January 2018

1 reference

Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts

21 January 2018

1 reference

Melatonin ameliorates ER stress-mediated hepatic steatosis through miR-23a in the liver

21 January 2018

1 reference

Gene expression profiling indicate role of ER stress in miR-23a~27a~24-2 cluster induced apoptosis in HEK293T cells

21 January 2018

1 reference

Endoplasmic reticulum stress signaling: the microRNA connection

21 January 2018

1 reference

Recent developments in acute liver failure

21 January 2018

1 reference

Melatonin attenuates inflammation and promotes regeneration in rabbits with fulminant hepatitis of viral origin.

21 January 2018

1 reference

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

21 January 2018

1 reference

Melatonin inhibits autophagy and endoplasmic reticulum stress in mice with carbon tetrachloride-induced fibrosis.

21 January 2018

1 reference

Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy

21 January 2018

1 reference

Melatonin alleviates lipopolysaccharide-induced placental cellular stress response in mice

21 January 2018

1 reference

Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

Melatonin Reverses Fas, E2F-1 and Endoplasmic Reticulum Stress Mediated Apoptosis and Dysregulation of Autophagy Induced by the Herbicide Atrazine in Murine Splenocytes

21 January 2018

1 reference

Intracellular calcium level required for calpain activation in a single myocardial cell

21 January 2018

1 reference

Type 2 diabetes mellitus: Role of melatonin and oxidative stress

21 January 2018

1 reference

Melatonin prevents pancreatic β-cell loss due to glucotoxicity: the relationship between oxidative stress and endoplasmic reticulum stress.

21 January 2018

1 reference

Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling

21 January 2018

1 reference

Melatonin-mediated insulin synthesis during endoplasmic reticulum stress involves HuD expression in rat insulinoma INS-1E cells

21 January 2018

1 reference

Arsenic trioxide in patients with hepatocellular carcinoma: a phase II trial

21 January 2018

1 reference