(Q38618638)

4 September 2017

Oligonucleotide therapeutics: chemistry, delivery and clinical progress (English)

1 reference

4 September 2017

2

1 reference

4 September 2017

Vivek K Sharma

1

1 reference

4 September 2017

29 October 2015

1 reference

Future Medicinal Chemistry

4 September 2017

1 reference

4 September 2017

7

1 reference

4 September 2017

16

1 reference

4 September 2017

2221-2242

1 reference

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

4 September 2017

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Silencing disease genes in the laboratory and the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Mipomersen sodium: first global approval

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Designing chemically modified oligonucleotides for targeted gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Clinical pharmacokinetics of second generation antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Complications in patients after intravitreal injection of bevacizumab.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Aptamer-based therapeutics of the past, present and future: from the perspective of eye-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Does inhibition of apolipoprotein B synthesis produce foie gras?

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Cellular delivery of siRNA and antisense oligonucleotides via receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Targeted delivery systems for oligonucleotide therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

siRNA and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Prodrugs: design and clinical applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Oligonucleotide delivery: a patent review (2010 - 2013).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Dacarbazine with or without oblimersen (a Bcl-2 antisense oligonucleotide) in chemotherapy-naive patients with advanced melanoma and low-normal serum lactate dehydrogenase: 'The AGENDA trial'

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Backbone modification of nucleic acids: synthesis, structure and therapeutic applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Incorporation of positively charged linkages into DNA and RNA backbones: a novel strategy for antigene and antisense agents

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Phosphorothioates, essential components of therapeutic oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Phosphorothioate oligodeoxynucleotides: what is their origin and what is unique about them?

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Physicochemical properties of phosphorothioate oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Antisense therapeutics: from theory to clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Stereodifferentiation--the effect of P chirality of oligo(nucleoside phosphorothioates) on the activity of bacterial RNase H.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Analysis of thermal melting curves.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Thermodynamic characterization of deoxyribooligonucleotide duplexes containing bulges.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Absorbance melting curves of RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Thermodynamic criteria for high hit rate antisense oligonucleotide design

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Improved Estimation of Secondary Structure in Ribonucleic Acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Nearest neighbor parameters for Watson-Crick complementary heteroduplexes formed between 2'-O-methyl RNA and RNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Short antisense oligonucleotides with novel 2'-4' conformationaly restricted nucleoside analogues show improved potency without increased toxicity in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Triazole-Linked Analogue of Deoxyribonucleic Acid (TLDNA): Design, Synthesis, and Double-Strand Formation with Natural DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Synthesis of triazole-linked oligonucleotides with high affinity to DNA complements and an analysis of their compatibility with biosystems.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Synthesis and hybridization data of oligonucleotide analogs with triazole internucleotide linkages, potential antiviral and antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

An overview of sugar-modified oligonucleotides for antisense therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Chemical modification of small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Silencing or stimulation? siRNA delivery and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Perspectives on chemistry and therapeutic applications of Locked Nucleic Acid (LNA).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Discovering the first microRNA-targeted drug

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Silencing of microRNA families by seed-targeting tiny LNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

A Kinetic Model Explains Why Shorter and Less Affine Enzyme-recruiting Oligonucleotides Can Be More Potent

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Fine tuning of electrostatics around the internucleotidic phosphate through incorporation of modified 2',4'-carbocyclic-LNAs and -ENAs leads to significant modulation of antisense properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Design, synthesis, and properties of 2',4'-BNA(NC): a bridged nucleic acid analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA.RNA hybrid duplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Structural requirements at the catalytic site of the heteroduplex substrate for human RNase H1 catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides (2'F-ANA): synthesis and physicochemical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Synthesis and properties of 2'-deoxy-2',4'-difluoroarabinose-modified nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

alpha-L-ribo-configured locked nucleic acid (alpha-L-LNA): synthesis and properties

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

The Eight Stereoisomers of LNA (Locked Nucleic Acid): A Remarkable Family of Strong RNA Binding Molecules We acknowledge the Danish Natural Science Research Council, the Danish Technical Research Council, and Exiqon A/S for financial support. Ms Bri

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

NMR structure of an -L-LNA:RNA hybrid: structural implications for RNase H recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Crystal structure of double helical hexitol nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Synthesis, Improved Antisense Activity and Structural Rationale for the Divergent RNA Affinities of 3′-Fluoro Hexitol Nucleic Acid (FHNA and Ara-FHNA) Modified Oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Improved hybridisation potential of oligonucleotides comprising O-methylated anhydrohexitol nucleoside congeners

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

RNase H mediated cleavage of RNA by cyclohexene nucleic acid (CeNA).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Cyclohexene Nucleic Acids (CeNA): Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Oxepane nucleic acids: synthesis, characterization, and properties of oligonucleotides bearing a seven-membered carbohydrate ring.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Eteplirsen for the treatment of Duchenne muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Efficient splicing correction by PNA conjugation to an R6-Penetratin delivery peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Heterocyclic modifications of oligonucleotides and antisense technology.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Chemical modification of siRNA bases to probe and enhance RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Toll-like receptors in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Activation of toll-like receptor 9 by DNA from different bacterial species

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Site and mechanism of antisense inhibition by C-5 propyne oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Evaluation of C-5 propynyl pyrimidine-containing oligonucleotides in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

C5-amino acid functionalized LNA: positively poised for antisense applications

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Carbohydrate-functionalized locked nucleic acids: oligonucleotides with extraordinary binding affinity, target specificity, and enzymatic stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Cellular penetration and antisense activity by a phenoxazine-substituted heptanucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

A Cytosine Analogue Capable of Clamp-Like Binding to a Guanine in Helical Nucleic Acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

20 years of lipid nanoparticles (SLN and NLC): present state of development and industrial applications

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Polycation-based nanoparticle delivery of RNAi therapeutics: adverse effects and solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Advanced transfection with Lipofectamine 2000 reagent: primary neurons, siRNA, and high-throughput applications

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Synthetic nucleic acid delivery systems: present and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Lipoplex morphologies and their influences on transfection efficiency in gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Three-Dimensional Imaging of Lipid Gene-Carriers: Membrane Charge Density Controls Universal Transfection Behavior in Lamellar Cationic Liposome-DNA Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Supramolecular assemblies in functional siRNA delivery: where do we stand?

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

RNAi-based nanomedicines for targeted personalized therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Rational design of cationic lipids for siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Nonviral delivery of self-amplifying RNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Preclinical and clinical development of siRNA-based therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

A review of stimuli-responsive nanocarriers for drug and gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

On the role of methacrylic acid copolymers in the intracellular delivery of antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

pH-responsive polymeric micelle carriers for siRNA drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Folate receptor targeted delivery of polyelectrolyte complex micelles prepared from ODN-PEG-folate conjugate and cationic lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Anti-CD22 antibody targeting of pH-responsive micelles enhances small interfering RNA delivery and gene silencing in lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

A biodegradable pH-sensitive micelle system for targeting acidic solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Nanoparticle-aptamer bioconjugates for cancer targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Nucleic acid aptamer-mediated drug delivery for targeted cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

The prostate-specific membrane antigen: lessons and current clinical implications from 20 years of research

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Aptamer mediated siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

The Ashwell-Morell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

siRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Efficient Synthesis and Biological Evaluation of 5'-GalNAc Conjugated Antisense Oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Hybrid lipid oligonucleotide conjugates: synthesis, self-assemblies and biomedical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

MicroRNAs 103 and 107 regulate insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Chimeric Antisense Oligonucleotide Conjugated to α-Tocopherol

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Delivery of short interfering RNA using endosomolytic cell-penetrating peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

The influence of net charge and charge distribution on cellular uptake and cytosolic localization of arginine-rich peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Cell penetrating peptide conjugates of steric block oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Prevention of dystrophic pathology in severely affected dystrophin/utrophin-deficient mice by morpholino-oligomer-mediated exon-skipping

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Improved cellular activity of antisense peptide nucleic acids by conjugation to a cationic peptide-lipid (CatLip) domain

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Small efficient cell-penetrating peptides derived from scorpion toxin maurocalcine

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

A DNA-based method for rationally assembling nanoparticles into macroscopic materials

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Oligonucleotide-modified gold nanoparticles for intracellular gene regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Polyvalent DNA nanoparticle conjugates stabilize nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Five years of siRNA delivery: spotlight on gold nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Gene regulation with polyvalent siRNA-nanoparticle conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Gold nanoparticles for biology and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Scavenger receptors mediate cellular uptake of polyvalent oligonucleotide-functionalized gold nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Antibody-linked spherical nucleic acids for cellular targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Silver nanoparticle-oligonucleotide conjugates based on DNA with triple cyclic disulfide moieties

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Polyvalent oligonucleotide iron oxide nanoparticle "click" conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

A reactive peptidic linker for self-assembling hybrid quantum dot-DNA bioconjugates.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Spherical nucleic acids: a whole new ball game

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Liposomal spherical nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Immunomodulatory spherical nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Programmable RNA recognition and cleavage by CRISPR/Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

On the in vitro and in vivo Properties of Four Locked Nucleic Acid Nucleotides Incorporated into an Anti-H-Ras Antisense Oligonucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

Synthesis of 3‘-C- and 4‘-C-Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.15.144

21 January 2018

Identifiers

DOI

10.4155/FMC.15.144

1 reference

4 September 2017

1 reference

PubMed ID

26510815