(Q38646326)

5 September 2017

title

The blood-brain barrier in psychosis (English)

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5 September 2017

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1 reference

5

1 reference

5 September 2017

James M Stone

3

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author name string

Thomas A Pollak

1

1 reference

5 September 2017

Svetlana Drndarski

2

1 reference

5 September 2017

Anthony S David

4

1 reference

5 September 2017

N Joan Abbott

6

1 reference

5 September 2017

publication date

3 August 2017

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5 September 2017

published in

The Lancet Psychiatry

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Structure and function of the blood-brain barrier

5 September 2017

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The choroid plexus is modulated by various peripheral stimuli: implications to diseases of the central nervous system

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Status epilepticus, blood-brain barrier disruption, inflammation, and epileptogenesis

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7 January 2021

Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke

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7 January 2021

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Cellular response of the blood-brain barrier to injury: Potential biomarkers and therapeutic targets for brain regeneration

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7 January 2021

Examining the Uptake of Central Nervous System Drugs and Candidates across the Blood-Brain Barrier.

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7 January 2021

Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections

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7 January 2021

Plasma levels of mature brain-derived neurotrophic factor (BDNF) and matrix metalloproteinase-9 (MMP-9) in treatment-resistant schizophrenia treated with clozapine

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7 January 2021

Regional increase in P-glycoprotein function in the blood-brain barrier of patients with chronic schizophrenia: a PET study with [(11)C]verapamil as a probe for P-glycoprotein function

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7 January 2021

Morphometric analysis of the cerebral expression of ATP-binding cassette transporter protein ABCB1 in chronic schizophrenia: Circumscribed deficits in the habenula

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7 January 2021

Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature

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7 January 2021

A weak association of the CLDN5 locus with schizophrenia in Chinese case-control samples

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7 January 2021

Further study of a genetic association between the CLDN5 locus and schizophrenia

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7 January 2021

The CLDN5 locus may be involved in the vulnerability to schizophrenia

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7 January 2021

Elevated expression of integrin alpha(IIb) beta(IIIa) in drug-naïve, first-episode schizophrenic patients.

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7 January 2021

Markers of thrombogenesis are activated in unmedicated patients with acute psychosis: a matched case control study

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7 January 2021

Increased levels of serum soluble L-selectin in unmedicated patients with schizophrenia

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7 January 2021

Decreased levels of soluble intercellular adhesion molecule-1 (sICAM-1) in unmedicated and medicated schizophrenic patients

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7 January 2021

Blood-cerebrospinal fluid barrier impairment as indicator for an immune process in schizophrenia

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7 January 2021

The Choroid Plexus in Healthy and Diseased Brain

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7 January 2021

Diffusion of macromolecules in the brain: implications for drug delivery

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7 January 2021

Probing the extracellular diffusion of antibodies in brain using in vivo integrative optical imaging and ex vivo fluorescence imaging

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7 January 2021

Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology

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7 January 2021

Evidence for a 'paravascular' fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space

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7 January 2021

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

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7 January 2021

Mechanisms of fluid movement into, through and out of the brain: evaluation of the evidence

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7 January 2021

Spatial model of convective solute transport in brain extracellular space does not support a "glymphatic" mechanism.

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7 January 2021

The movers and shapers in immune privilege of the CNS.

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7 January 2021

Detection and quantification of microRNA in cerebral microdialysate

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7 January 2021

Amyloid-β and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus

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7 January 2021

Cerebrospinal fluid and lumbar puncture: a practical review

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7 January 2021

Utility of CSF in translational neuroscience.

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7 January 2021

Cerebrospinal fluid analysis in affective and schizophrenic spectrum disorders: identification of subgroups with immune responses and blood-CSF barrier dysfunction

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7 January 2021

IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia

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7 January 2021

Postmortem brain: an underutilized substrate for studying severe mental illness

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7 January 2021

The cerebral microvasculature in schizophrenia: a laser capture microdissection study

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7 January 2021

Neuroinflammation and white matter pathology in schizophrenia: systematic review.

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7 January 2021

Deficit of pericapillary oligodendrocytes in the prefrontal cortex in schizophrenia.

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7 January 2021

Immunohistochemical localization of phosphorylated glial fibrillary acidic protein in the prefrontal cortex and hippocampus from patients with schizophrenia, bipolar disorder, and depression.

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7 January 2021

Glial fibrillary acidic protein mRNA levels in the cingulate cortex of individuals with depression, bipolar disorder and schizophrenia

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7 January 2021

Different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: further evidence for disease course-related immune alterations?

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7 January 2021

Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia

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7 January 2021

Transcriptome sequencing of the choroid plexus in schizophrenia

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7 January 2021

Blood-based biomarkers for traumatic brain injury: evaluation of research approaches, available methods and potential utility from the clinician and clinical laboratory perspectives

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7 January 2021

Serum S100B Is Related to Illness Duration and Clinical Symptoms in Schizophrenia-A Meta-Regression Analysis.

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7 January 2021

Systematic review and meta-analysis of circulating S100B blood levels in schizophrenia

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7 January 2021

S100B serum levels are closely correlated with body mass index: an important caveat in neuropsychiatric research

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7 January 2021

A positive correlation between serum levels of mature brain-derived neurotrophic factor and negative symptoms in schizophrenia.

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7 January 2021

Blood-brain barrier imaging in human neuropathologies

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7 January 2021

Choroid plexus calcification as a possible marker of hallucinations in schizophrenia

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7 January 2021

Calcification of the choroid plexus as a marker of depression in schizophrenia

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7 January 2021

Gadolinium-DTPA enhanced gradient echo magnetic resonance scans in first episode of psychosis and chronic schizophrenic patients

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7 January 2021

Blood-brain barrier breakdown in the aging human hippocampus

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7 January 2021

Assessment of cerebral blood volume in schizophrenia: A magnetic resonance imaging study

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7 January 2021

The impact of schizophrenia on frontal perfusion parameters: a DSC-MRI study

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7 January 2021

Translating the MAM model of psychosis to humans

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7 January 2021

Nature of Glutamate Alterations in Schizophrenia: A Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies

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7 January 2021

Glutamate-Mediated Blood-Brain Barrier Opening: Implications for Neuroprotection and Drug Delivery

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7 January 2021

Na(+)-dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) of the blood-brain barrier. A mechanism for glutamate removal

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7 January 2021

Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons?

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7 January 2021

Common variants in SLC1A2 and schizophrenia: Association and cognitive function in patients with schizophrenia and healthy individuals

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7 January 2021

Effect of glutamate transporter EAAT2 gene variants and gray matter deficits on working memory in schizophrenia

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7 January 2021

Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp120.

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7 January 2021

Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects

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7 January 2021

Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment

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7 January 2021

Biological insights from 108 schizophrenia-associated genetic loci

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7 January 2021

The epidemiologic evidence linking autoimmune diseases and psychosis.

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7 January 2021

Autoimmune diseases and infections as risk factors for schizophrenia

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7 January 2021

Prenatal maternal infection, neurodevelopment and adult schizophrenia: a systematic review of population-based studies

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7 January 2021

Are some cases of psychosis caused by microbial agents? A review of the evidence

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7 January 2021

A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression

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7 January 2021

Cortisol and Inflammatory Biomarkers Predict Poor Treatment Response in First Episode Psychosis

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7 January 2021

Towards a psychosis risk blood diagnostic for persons experiencing high-risk symptoms: preliminary results from the NAPLS project

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7 January 2021

Involvement of ROS in BBB dysfunction

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7 January 2021

IL-1beta regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program

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7 January 2021

Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier

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7 January 2021

Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A "central hub" in schizophrenia pathophysiology?

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7 January 2021

Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [(11)C]PBR28 PET Brain Imaging Study.

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7 January 2021

Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization

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7 January 2021

Autoantibodies to central nervous system neuronal surface antigens: psychiatric symptoms and psychopharmacological implications

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7 January 2021

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

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7 January 2021

Frequency and characteristics of isolated psychiatric episodes in anti–N-methyl-d-aspartate receptor encephalitis

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7 January 2021

Prevalence of anti-N-methyl-D-aspartate (NMDA) receptor [corrected] antibodies in patients with schizophrenia and related psychoses: a systematic review and meta-analysis

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7 January 2021

Do neuronal autoantibodies cause psychosis? A neuroimmunological perspective

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7 January 2021

Immunotherapy for patients with acute psychosis and serum N-Methyl D-Aspartate receptor (NMDAR) antibodies: a description of a treated case series

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7 January 2021

Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity

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7 January 2021

Apolipoprotein E4 carrier status plus circulating anti-NMDAR1 autoantibodies: association with schizoaffective disorder

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7 January 2021

Immunity and behavior: antibodies alter emotion

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7 January 2021

Immunological findings in psychotic syndromes: a tertiary care hospital's CSF sample of 180 patients

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7 January 2021

Increased frequency of activated lymphocytes in the cerebrospinal fluid of patients with acute schizophrenia

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7 January 2021

Increased frequency of CD8 positive gamma/delta T-lymphocytes (CD8+ gamma/delta+) in unmedicated schizophrenic patients: relation to impairment of the blood-brain barrier and HLA-DPA*02011.

1 reference

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7 January 2021

Review: Role of developmental inflammation and blood-brain barrier dysfunction in neurodevelopmental and neurodegenerative diseases.

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7 January 2021

The blood-brain barrier in systemic inflammation

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7 January 2021

Obstetric complications and schizophrenia: historical and meta-analytic review

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7 January 2021

Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation

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7 January 2021

Initiation of resuscitation with high tidal volumes causes cerebral hemodynamic disturbance, brain inflammation and injury in preterm lambs

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7 January 2021

Is traumatic brain injury a risk factor for schizophrenia? A meta-analysis of case-controlled population-based studies.

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7 January 2021

Consequences of repeated blood-brain barrier disruption in football players

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7 January 2021

Does tobacco use cause psychosis? Systematic review and meta-analysis

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7 January 2021

Pathophysiological impact of cigarette smoke exposure on the cerebrovascular system with a focus on the blood-brain barrier: expanding the awareness of smoking toxicity in an underappreciated area

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7 January 2021

Amphetamine-induced psychosis--a separate diagnostic entity or primary psychosis triggered in the vulnerable?

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7 January 2021

Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress

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7 January 2021

Psychosis in epilepsy patients and other chronic medically ill patients and the role of cerebral pathology in the onset of psychosis: a clinical epidemiological study

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7 January 2021

Seizure-induced brain-borne inflammation sustains seizure recurrence and blood-brain barrier damage.

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7 January 2021

Intracellular and circulating neuronal antinuclear antibodies in human epilepsy

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7 January 2021

Environment and schizophrenia: environmental factors in schizophrenia: childhood trauma--a critical review

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7 January 2021

Does Systemic Inflammation Play a Role in Pediatric Psychosis?

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Premorbid adjustment and personality in people with schizophrenia†

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Estrogen, menstrual cycle phases, and psychopathology in women suffering from schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Estrogen protects the blood-brain barrier from inflammation-induced disruption and increased lymphocyte trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Pre-eclampsia and first-onset postpartum psychiatric episodes: a Danish population-based cohort study.

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Plasma from preeclamptic women increases blood-brain barrier permeability: role of vascular endothelial growth factor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

High rates of schizophrenia in adults with velo-cardio-facial syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Adversity in childhood linked to elevated striatal dopamine function in adulthood

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function.

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Relationship between P-glycoprotein and second-generation antipsychotics.

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

P-glycoprotein interaction with risperidone and 9-OH-risperidone studied in vitro, in knock-out mice and in drug-drug interaction experiments

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

The brain entry of risperidone and 9-hydroxyrisperidone is greatly limited by P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Two distinct patterns of treatment resistance: clinical predictors of treatment resistance in first-episode schizophrenia spectrum psychoses.

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Drug resistance in brain diseases and the role of drug efflux transporters.

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Mannose 6-phosphate receptors: new twists in the tale

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Biotransformation of Post-Clozapine Antipsychotics

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancy

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Microglial activation in the rat brain following chronic antipsychotic treatment at clinically relevant doses

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

The myth of schizophrenia as a progressive brain disease

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Electroconvulsive therapy, hypertensive surge, blood-brain barrier breach, and amnesia: exploring the evidence for a connection

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Sex hormones and oxytocin augmentation strategies in schizophrenia: A quantitative review.

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

Intracerebral adult stem cells transplantation increases brain-derived neurotrophic factor levels and protects against phencyclidine-induced social deficit in mice

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

In-vivo imaging of blood-brain barrier permeability using positron emission tomography with 2-amino-[3-11C]isobutyric acid

1 reference

https://api.crossref.org/works/10.1016%2FS2215-0366%2817%2930293-6

7 January 2021

10.1016/S2215-0366(17)30293-6

Identifiers

DOI

1 reference

5 September 2017

1 reference