(Q38414396)

English

Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature

scientific article published on July 2015

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scholarly article

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Europe PubMed Central

2 September 2017

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Europe PubMed Central

Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature (English)

1 reference

Europe PubMed Central

2 September 2017

5

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Europe PubMed Central

2 September 2017

Elke Schaeffeler

2

object named as

Elke Schaeffeler

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author name string

Stefan Wolking

1

1 reference

Europe PubMed Central

2 September 2017

Holger Lerche

3

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Europe PubMed Central

2 September 2017

Matthias Schwab

4

1 reference

Europe PubMed Central

2 September 2017

publication date

1 July 2015

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Europe PubMed Central

2 September 2017

Clinical Pharmacokinetics

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Europe PubMed Central

2 September 2017

54

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Europe PubMed Central

2 September 2017

7

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Europe PubMed Central

2 September 2017

709-735

1 reference

Europe PubMed Central

2 September 2017

https://scigraph.springernature.com/pub.10.1007/s40262-015-0267-1

0 references

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance

1 reference

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21 January 2018

Functional significance of genetic polymorphisms in P-glycoprotein (MDR1, ABCB1) and breast cancer resistance protein (BCRP, ABCG2).

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21 January 2018

MDR1 genotype-related pharmacokinetics: fact or fiction?

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21 January 2018

Genetic polymorphisms of the human MDR1 drug transporter

1 reference

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21 January 2018

An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics.

1 reference

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21 January 2018

A "silent" polymorphism in the MDR1 gene changes substrate specificity

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The MDR1 (ABCB1) gene polymorphism and its clinical implications

1 reference

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21 January 2018

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

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21 January 2018

The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research

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21 January 2018

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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21 January 2018

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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21 January 2018

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

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21 January 2018

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

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21 January 2018

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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21 January 2018

Expression of a multidrug-resistance gene in human tumors and tissues

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21 January 2018

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

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21 January 2018

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

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21 January 2018

Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system

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21 January 2018

Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells

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21 January 2018

Regulation of volume-activated chloride channels by P-glycoprotein: phosphorylation has the final say!

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21 January 2018

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

1 reference

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21 January 2018

Is the multidrug transporter a flippase?

1 reference

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21 January 2018

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

1 reference

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21 January 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

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21 January 2018

Quantification and characterization of P-glycoprotein-substrate interactions

1 reference

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21 January 2018

Clinical aspects of the MDR1 (ABCB1) gene polymorphism

1 reference

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21 January 2018

Pharmacogenetics of ATP-binding cassette transporters and clinical implications

1 reference

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21 January 2018

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

1 reference

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21 January 2018

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Dipyridamole enhances digoxin bioavailability via P-glycoprotein inhibition

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21 January 2018

Meta-analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1 gene expression

1 reference

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21 January 2018

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.

1 reference

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21 January 2018

An integrated map of genetic variation from 1,092 human genomes

1 reference

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21 January 2018

A novel MDR1 G1199T variant alters drug resistance and efflux transport activity of P-glycoprotein in recombinant Hek cells

1 reference

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21 January 2018

Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay

1 reference

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21 January 2018

Substrate-dependent effects of human ABCB1 coding polymorphisms

1 reference

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21 January 2018

Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

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21 January 2018

A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.

1 reference

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21 January 2018

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

1 reference

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21 January 2018

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Identification of functionally variant MDR1 alleles among European Americans and African Americans

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21 January 2018

Frequency of C3435T polymorphism of MDR1 gene in African people

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21 January 2018

Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene

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21 January 2018

Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan

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21 January 2018

Genomic evidence for recent positive selection at the human MDR1 gene locus

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21 January 2018

Exon sequencing and high resolution haplotype analysis of ABC transporter genes implicated in drug resistance

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21 January 2018

MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer

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21 January 2018

Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens

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21 January 2018

Sex is a major determinant of CYP3A4 expression in human liver

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Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver.

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21 January 2018

Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex

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21 January 2018

ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.

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21 January 2018

C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

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21 January 2018

Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms

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21 January 2018

Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver

1 reference

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21 January 2018

Common single nucleotide polymorphisms of the MDR1 gene have no influence on its mRNA expression level of normal kidney cortex and renal cell carcinoma in Japanese nephrectomized patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

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21 January 2018

Gene-wide characterization of common quantitative trait loci for ABCB1 mRNA expression in normal liver tissues in the Chinese population

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

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21 January 2018

Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)

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21 January 2018

Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients

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21 January 2018

Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes

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21 January 2018

Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations

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21 January 2018

Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression

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21 January 2018

ABCB1 (MDR1) polymorphisms and antidepressant response in geriatric depression

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21 January 2018

Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I.

1 reference

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21 January 2018

Effects of genetic polymorphisms of CYP3A4, CYP3A5 and MDR1 on cyclosporine pharmacokinetics after renal transplantation.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR-1 C3435T polymorphism influences cyclosporine a dose requirement in liver-transplant recipients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR1 C3435T polymorphisms correlate with cyclosporine levels in de novo renal recipients.

1 reference

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21 January 2018

The Effect of ABCB1 C3435T Polymorphism on Cyclosporine Dose Requirements in Kidney Transplant Recipients: A Meta-Analysis

1 reference

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21 January 2018

Influence of ABCB1 genetic polymorphisms on cyclosporine intracellular concentration in transplant recipients.

1 reference

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21 January 2018

ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation

1 reference

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21 January 2018

Donor P-gp polymorphisms strongly influence renal function and graft loss in a cohort of renal transplant recipients on cyclosporine therapy in a long-term follow-up.

1 reference

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21 January 2018

ABCB1 genotypes predict cyclosporine-related adverse events and kidney allograft outcome

1 reference

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21 January 2018

Donor ABCB1 variant associates with increased risk for kidney allograft failure

1 reference

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21 January 2018

Significant impact of gene polymorphisms on tacrolimus but not cyclosporine dosing in Asian renal transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Influence of different allelic variants of the CYP3A and ABCB1 genes on the tacrolimus pharmacokinetic profile of Chinese renal transplant recipients

1 reference

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21 January 2018

Impact of ABCB1 (MDR1) haplotypes on tacrolimus dosing in adult lung transplant patients who are CYP3A5 *3/*3 non-expressors

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21 January 2018

Donor age and renal P-glycoprotein expression associate with chronic histological damage in renal allografts

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21 January 2018

ABCB1 Single-Nucleotide Polymorphisms Determine Tacrolimus Response in Patients With Ulcerative Colitis

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21 January 2018

Pharmacokinetics of paclitaxel in ovarian cancer patients and genetic polymorphisms of CYP2C8, CYP3A4, and MDR1.

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21 January 2018

Pharmacogenetic studies of Paclitaxel in the treatment of ovarian cancer

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21 January 2018

Influence of Cremophor EL and genetic polymorphisms on the pharmacokinetics of paclitaxel and its metabolites using a mechanism-based model.

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21 January 2018

CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.

1 reference

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21 January 2018

Association of ABCB1 genotypes with paclitaxel-mediated peripheral neuropathy and neutropenia

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21 January 2018

CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel

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21 January 2018

Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer

1 reference

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21 January 2018

Effect of ABCB1 C3435T polymorphism on docetaxel pharmacokinetics according to menopausal status in breast cancer patients.

1 reference

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21 January 2018

ABCB1 genetic variation influences the toxicity and clinical outcome of patients with androgen-independent prostate cancer treated with docetaxel

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21 January 2018

Side effects after docetaxel treatment in Taiwanese breast cancer patients with CYP3A4, CYP3A5, and ABCB1 gene polymorphisms

1 reference

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21 January 2018

Genetic Variations of Drug Transporters Can Influence on Drug Response in Patients Treated with Docetaxel Chemotherapy

1 reference

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21 January 2018

Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer.

1 reference

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21 January 2018

Pharmacogenetics of ABC and SLC transporters in metastatic colorectal cancer patients receiving first-line FOLFIRI treatment.

1 reference

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21 January 2018

Phase III trial of irinotecan/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer: clinical and pharmacogenomic results from SWOG S0124.

1 reference

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21 January 2018

MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models

1 reference

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21 January 2018

Polymorphisms in the multidrug resistance gene MDR1 (ABCB1) predict for molecular resistance in patients with newly diagnosed chronic myeloid leukemia receiving high-dose imatinib

1 reference

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21 January 2018

Multidrug resistance gene (MDR1) polymorphisms are associated with major molecular responses to standard-dose imatinib in chronic myeloid leukemia.

1 reference

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21 January 2018

Association of MDR1 gene polymorphism (G2677T) with imatinib response in Egyptian chronic myeloid leukemia patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 gene polymorphisms are not associated with treatment outcome in elderly acute myeloid leukemia patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Multidrug resistance-1 gene polymorphisms associated with treatment outcomes in de novo acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR1 polymorphism influences the outcome of multiple myeloma patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma

1 reference

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21 January 2018

Impact of genetic variation in breast cancer resistance protein (BCRP/ABCG2) on sunitinib pharmacokinetics

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Efflux pump ABCB1 single nucleotide polymorphisms and dose reductions in patients with metastatic renal cell carcinoma treated with sunitinib

1 reference

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21 January 2018

Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity

1 reference

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21 January 2018

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Genetic factors influencing severe atazanavir-associated hyperbilirubinemia in a population with low UDP-glucuronosyltransferase 1A1*28 allele frequency

1 reference

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21 January 2018

Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique

1 reference

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21 January 2018

Influence of ABCB1, ABCC1, ABCC2, and ABCG2 haplotypes on the cellular exposure of nelfinavir in vivo

1 reference

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21 January 2018

CYP2C19 genetic variants affect nelfinavir pharmacokinetics and virologic response in HIV-1-infected children receiving highly active antiretroviral therapy

1 reference

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21 January 2018

Multidrug resistance 1 polymorphisms and trough concentrations of atazanavir and lopinavir in patients with HIV.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Oral contraception does not alter single dose saquinavir pharmacokinetics in women

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Minimal effect of MDR1 and CYP3A5 genetic polymorphisms on the pharmacokinetics of indinavir in HIV-infected patients

1 reference

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21 January 2018

Pharmacokinetic study of the variability of indinavir drug levels when boosted with ritonavir in HIV-infected children

1 reference

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21 January 2018

Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate.

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21 January 2018

Genetic determinants of response to clopidogrel and cardiovascular events

1 reference

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21 January 2018

Platelet pharmacogenomics

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in plat

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Value of platelet pharmacogenetics in common clinical practice of patients with ST-segment elevation myocardial infarction

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The effects of CES1A2 A(-816)C and CYP2C19 loss-of-function polymorphisms on clopidogrel response variability among Chinese patients with coronary heart disease.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 C3435T polymorphism and response to clopidogrel treatment in coronary artery disease (CAD) patients: a meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Early identification of refractory epilepsy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

How to explain multidrug resistance in epilepsy?

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Cerebral expression of drug transporters in epilepsy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR1 gene expression in brain of patients with medically intractable epilepsy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Role of multidrug transporters in pharmacoresistance to antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Genetic factors associated with drug-resistance of epilepsy: relevance of stratification by patient age and aetiology of epilepsy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Lack of association between ABCB1 gene polymorphisms and pharmacoresistant epilepsy: an analysis in a western Chinese pediatric population

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Multidrug resistance 1 (MDR1) gene polymorphisms in childhood drug-resistant epilepsy.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

CYP3A5*3 and C3435T MDR1 polymorphisms in prognostication of drug-resistant epilepsy in children and adolescents

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

One of the hottest topics in epileptology: ABC proteins. Their inhibition may be the future for patients with intractable seizures

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Polymorphism of the MDR1/ABCB1 C3435T drug-transporter and resistance to anticonvulsant drugs: a meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Association of ABCB1 gene polymorphisms and their haplotypes with response to antiepileptic drugs: a systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Effects of ABCB1 polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Effects of major transporter and metabolizing enzyme gene polymorphisms on carbamazepine metabolism in Chinese patients with epilepsy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

G2677T polymorphism can predict treatment outcome of Malaysians with complex partial seizures being treated with Carbamazepine.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Role of MDR1 C3435T and GABRG2 C588T gene polymorphisms in seizure occurrence and MDR1 effect on anti-epileptic drug (phenytoin) absorption.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: a gene polymorphism perspective study

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Association of MDR1 C3435T polymorphism with bipolar disorder in patients treated with valproic acid

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Association between lamotrigine concentrations and ABCB1 polymorphisms in patients with epilepsy.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABC transporters in drug-refractory epilepsy: limited clinical significance of pharmacogenetics?

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Exploring the genomic basis of pharmacoresistance in epilepsy: an integrative analysis of large-scale gene expression profiling studies on brain tissue from epilepsy surgery

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Genetic biomarkers in epilepsy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The role of the transporter P-glycoprotein for disposition and effects of centrally acting drugs and for the pathogenesis of CNS diseases

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

abcb1ab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 C3435T polymorphism is associated with susceptibility to major depression, but not with a clinical response to citalopram in a Turkish population.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR1 gene polymorphism: therapeutic response to paroxetine among patients with major depression

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Effects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypes

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR1 gene polymorphisms and response to acute risperidone treatment

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The role of CYP2D6 and ABCB1 pharmacogenetics in drug-naïve patients with first-episode schizophrenia treated with risperidone

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 polymorphisms influence steady-state plasma levels of 9-hydroxyrisperidone and risperidone active moiety.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Effect of CYP2D6, CYP3A5, and MDR1 genetic polymorphisms on the pharmacokinetics of risperidone and its active moiety

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Polymorphisms of the ABCB1 gene are associated with the therapeutic response to risperidone in Chinese schizophrenia patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Omics and drug response

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Data collection as a barrier to personalized medicine

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Importance of P-glycoprotein at blood-tissue barriers

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Pharmacogenomics knowledge for personalized medicine

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Effect of the ABCB1 3435C>T polymorphism on tacrolimus concentrations and dosage requirements in liver transplant recipients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

1199G>A and 2677G>T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Influence of ABCB1 polymorphisms and haplotypes on tacrolimus nephrotoxicity and dosage requirements in children with liver transplant.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Genetic polymorphisms and individualized tacrolimus dosing

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Impact of cytochrome P450 3A and ATP-binding cassette subfamily B member 1 polymorphisms on tacrolimus dose-adjusted trough concentrations among Korean renal transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Influence of the CYP3A5 and MDR1 genetic polymorphisms on the pharmacokinetics of tacrolimus in healthy Korean subjects

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

CYP3A5 and ABCB1 Polymorphisms and Tacrolimus Pharmacokinetics in Renal Transplant Candidates: Guidelines from an Experimental Study

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

CYP3A5 genotype is not associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR1 haplotypes conferring an increased expression of intestinal CYP3A4 rather than MDR1 in female living-donor liver transplant patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Tacrolimus concentrations in relation to CYP3A and ABCB1 polymorphisms among solid organ transplant recipients in Korea

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Tacrolimus dose requirements and CYP3A5 genotype and the development of calcineurin inhibitor-associated nephrotoxicity in renal allograft recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

CYP3A5 *1 allele: impacts on early acute rejection and graft function in tacrolimus-based renal transplant recipients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The influence of genetic polymorphisms of cytochrome P450 3A5 and ABCB1 on starting dose- and weight-standardized tacrolimus trough concentrations after kidney transplantation in relation to renal function

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Influence of CYP3A4, CYP3A5 and MDR-1 polymorphisms on tacrolimus pharmacokinetics and early renal dysfunction in liver transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Influence of CYP3A5 and MDR1 polymorphisms on tacrolimus concentration in the early stage after renal transplantation

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Population pharmacokinetics of everolimus in cardiac recipients: comedications, ABCB1, and CYP3A5 polymorphisms

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Haplotypic structure of ABCB1/MDR1 gene modifies the risk of the acute allograft rejection in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 polymorphisms are associated with cyclosporine-induced nephrotoxicity and gingival hyperplasia in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ATP-binding cassette subfamily B member 1 polymorphisms do not determine cyclosporin exposure, acute rejection or nephrotoxicity after heart transplantation.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Effect of genetic polymorphisms of CYP3A5 and MDR1 on cyclosporine concentration during the early stage after renal transplantation in Chinese patients co-treated with diltiazem

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Amlodipine, but not MDR1 polymorphisms, alters the pharmacokinetics of cyclosporine A in Japanese kidney transplant recipients1

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

MDR1 haplotypes do not affect the steady-state pharmacokinetics of cyclosporine in renal transplant patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

CYP3A5 polymorphism and the ethnic differences in cyclosporine pharmacokinetics in healthy subjects.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Explaining variability in ciclosporin exposure in adult kidney transplant recipients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Correlation of aldo-ketoreductase (AKR) 1C3 genetic variant with doxorubicin pharmacodynamics in Asian breast cancer patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Population pharmacokinetics/pharmacodynamics of erlotinib and pharmacogenomic analysis of plasma and cerebrospinal fluid drug concentrations in Japanese patients with non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Single nucleotide polymorphism of multidrug-resistance 1 and anti- multidrug-resistance 1 single chain antibody treatment for the pancreatic cancer cell line

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 G1199A polymorphism and ovarian cancer response to paclitaxel.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 gene polymorphisms are associated with fatal intoxications involving venlafaxine but not citalopram

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of levosulpiride in healthy subjects

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Associations between MDR1 gene polymorphisms and schizophrenia and therapeutic response to olanzapine in female schizophrenic patients.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure--an impact similar to male gender or smoking in schizophrenic patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The relationship between P-glycoprotein (PGP) polymorphisms and response to olanzapine treatment in schizophrenia.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The influence of 5-HT(2C) and MDR1 genetic polymorphisms on antipsychotic-induced weight gain in female schizophrenic patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Antidepressants and ABCB1 gene C3435T functional polymorphism: a naturalistic study.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Factors impacting the expression of membrane-bound proteins in lymphocytes from HIV-positive subjects

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

The Effect of CYP3A5 and MDR1 Polymorphic Expression on Cyclosporine Oral Disposition in Renal Transplant Patients

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Imatinib Disposition and ABCB1 (MDR1, P-Glycoprotein) Genotype

1 reference

https://api.crossref.org/works/10.1007%2FS40262-015-0267-1

21 January 2018

Influence of ABCB1 and ABCG2 polymorphisms on doxorubicin disposition in Asian breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of C3435T polymorphism of ABCB1 gene on penetration of phenobarbital across the blood-brain barrier in patients with generalized epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors influencing efavirenz and nevirapine plasma concentration: effect of ethnicity, weight and co-medication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug resistance in epilepsy: why is a simple explanation not enough?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the ABCB1 gene polymorphisms 2677G>T/A and 3435C>T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of common ABCB1 polymorphism on pharmacokinetics and pharmacodynamics of clopidogrel and its metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of donor and recipient CYP3A5 and ABCB1 genetic polymorphisms on tacrolimus dosage requirements and rejection in Caucasian Spanish liver transplant patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex is a major determinant of CYP3A4 expression in human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure to confirm association of a polymorphism in ABCB1 with multidrug-resistant epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 are not associated with cyclosporine pharmacokinetics nor with cyclosporine clinical end points after renal transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors associated with health-related quality of life among outpatients with major depressive disorder: a STAR*D report.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of CYP3A5, CYP3A4, and ABCB1 genotypes as determinants of tacrolimus dose and clinical outcomes after heart transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCB1 and ABCG2 proteins, their functional activity and gene expression in concert with drug sensitivity of leukemia cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significant genetic linkage of MDR1 polymorphisms at positions 3435 and 2677: functional relevance to pharmacokinetics of digoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of CYP3A5 and ABCB1 gene polymorphisms and other factors on tacrolimus dosing in Caucasian liver and kidney transplant patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human P-glycoprotein transports cyclosporin A and FK506.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C3435T polymorphism of the MDR1 gene is not associated with P-glycoprotein function of leukemic blasts and clinical outcome in patients with acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between ABCB1 polymorphism and response to sodium valproate treatment in Malaysian epilepsy patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of CYP3A5 and ABCB1 single nucleotide polymorphisms on tacrolimus dose requirements in Caucasian liver transplant patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphism of the multidrug resistance 1 gene MDR1/ABCB1 C3435T and response to antiepileptic drug treatment in temporal lobe epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tacrolimus pharmacokinetics and pharmacogenetics: influence of adenosine triphosphate-binding cassette B1 (ABCB1) and cytochrome (CYP) 3A polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular risk among patients on clopidogrel anti-platelet therapy after placement of drug-eluting stents is modified by genetic variants in both the CYP2C19 and ABCB1 genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyp3A4, Cyp3A5, and MDR-1 genetic influences on tacrolimus pharmacokinetics in renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of MDR1 G2677T/A polymorphism on pharmacokinetics of gabapentin in healthy Korean subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCB1 gene polymorphisms are associated with the severity of major depressive disorder and its response to escitalopram treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of plasma and intracellular exposure and CYP3A4, CYP3A5, and ABCB1 genetic polymorphisms on vincristine-induced neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of P-glycoprotein on clopidogrel absorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of a side effect and efficacy of adjuvant chemotherapy with gemcitabine for post operative patient of pancreatic cancer by a genetic polymorphism analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential Influences of Leukemia-Specific and Genetic Factors on P-Glycoprotein Expression in Blasts from 817 Patients Entered into the National Cancer Research Network Acute Myeloid Leukemia 14 and 15 Trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do drug transporter (ABCB1) SNPs influence cyclosporine and tacrolimus dose requirements and renal allograft outcome in the posttransplantation period?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis of the effect of MDR1 C3435T polymorphism on cyclosporine pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional involvement of P-glycoprotein in blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of MDR1, CYP3A4*18B, and CYP3A5*3 polymorphisms with cyclosporine pharmacokinetics in Chinese renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDR1 genetic polymorphisms and comparison of MDR1 haplotype profiles in Korean and Vietnamese populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-glycosylation and deletion mutants of the human MDR1 P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the ABCB1 3435C>T polymorphism and treatment outcomes in advanced gastric cancer patients treated with paclitaxel-based chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Ef

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential phosphorylation patterns of P-glycoprotein reconstituted into a proteoliposome system: insight into additional unconventional phosphorylation sites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between cyclosporine concentration and genetic polymorphisms of CYP3A5 and MDR1 during the early stage after renal transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tacrolimus dose requirement in relation to donor and recipient ABCB1 and CYP3A5 gene polymorphisms in Chinese liver transplant patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of genetic polymorphisms on time required to attain the target tacrolimus levels and subsequent pharmacodynamic outcomes in pediatric kidney transplant patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of paclitaxel with carboplatin or gemcitabine, and effects of CYP3A5 and MDR1 polymorphisms in patients with urogenital cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance gene (MDR1) polymorphisms correlate with imatinib response in chronic myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms of tumor necrosis factor-alpha, interleukin-10, cytochrome P450 3A5 and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirements

1 reference

https://pubmed.ncbi.nlm.nih.gov/25860377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S40262-015-0267-1

1 reference

Europe PubMed Central

2 September 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

2 September 2017

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