(Q38796693)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27039308%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

Brain Iron Metabolism Dysfunction in Parkinson's Disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27039308%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

3

1 reference

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31 March 2020

author name string

Hong Jiang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27039308%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Jun Wang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27039308%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Junxia Xie

series ordinal

4

1 reference

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31 March 2020

publication date

2 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27039308%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

published in

Molecular Neurobiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27039308%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

volume

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27039308%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

issue

4

1 reference

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31 March 2020

page(s)

3078-3101

1 reference

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https://scigraph.springernature.com/pub.10.1007/s12035-016-9879-1

31 March 2020

exact match

0 references

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Restless legs syndrome: pathophysiology, clinical presentation and management

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Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive element

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Hippocampus specific iron deficiency alters competition and cooperation between developing memory systems

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The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons.

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Divalent metal transporter 1 up-regulation is involved in the 6-hydroxydopamine-induced ferrous iron influx

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Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells

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K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration

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Imaging neurodegeneration in Parkinson's disease

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Brain iron homeostasis

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Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells

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12 December 2020

Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function

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12 December 2020

Characterization of mitochondrial ferritin in Drosophila

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12 December 2020

Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron.

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12 December 2020

Modifications of the iron-neuromelanin system in Parkinson's disease

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Ndfip1 attenuated 6-OHDA-induced iron accumulation via regulating the degradation of DMT1.

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12 December 2020

Differential modulation of the RNA-binding proteins IRP-1 and IRP-2 in response to iron. IRP-2 inactivation requires translation of another protein

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12 December 2020

Distribution of ferroportin1 protein in different regions of developing rat brain

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12 December 2020

Neuromelanin can protect against iron-mediated oxidative damage in system modeling iron overload of brain aging and Parkinson's disease

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12 December 2020

Ferroportin1: a new iron export molecule?

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12 December 2020

Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis

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12 December 2020

Neurodegenerative diseases and oxidative stress

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12 December 2020

Cellular iron: ferroportin is the only way out

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12 December 2020

Lactoferrin is synthesized by mouse brain tissue and its expression is enhanced after MPTP treatment

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12 December 2020

Decreased iron levels in the temporal cortex in postmortem human brains with Parkinson disease

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12 December 2020

Voltage-gated calcium channels provide an alternate route for iron uptake in neuronal cell cultures

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12 December 2020

Effects of iron supplementation on attention deficit hyperactivity disorder in children.

1 reference

12 December 2020

Metal-catalyzed oxidation of alpha-synuclein: helping to define the relationship between oligomers, protofibrils, and filaments

1 reference

12 December 2020

Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappa B modulation in MES23.5 cells.

1 reference

12 December 2020

Hepcidin Suppresses Brain Iron Accumulation by Downregulating Iron Transport Proteins in Iron-Overloaded Rats.

1 reference

12 December 2020

MRI assessment of basal ganglia iron deposition in Parkinson's disease.

1 reference

12 December 2020

Iron homeostasis: fitting the puzzle pieces together

1 reference

12 December 2020

Iron-enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation

1 reference

12 December 2020

Ontogenic changes in lactoferrin receptor and DMT1 in mouse small intestine: implications for iron absorption during early life

1 reference

12 December 2020

Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson's disease: a LAMMA study

1 reference

12 December 2020

H and L ferritin subunit mRNA expression differs in brains of control and iron-deficient rats.

1 reference

12 December 2020

Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers

1 reference

12 December 2020

Iron is essential for neuron development and memory function in mouse hippocampus

1 reference

12 December 2020

Modeling N-methyl-D-aspartate-induced bursting in dopamine neurons

1 reference

12 December 2020

Astroglia overexpressing heme oxygenase-1 predispose co-cultured PC12 cells to oxidative injury.

1 reference

12 December 2020

Differential interaction between iron and mutant alpha-synuclein causes distinctive Parkinsonian phenotypes in Drosophila.

1 reference

12 December 2020

α-Synuclein as a ferrireductase

1 reference

12 December 2020

Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain

1 reference

12 December 2020

Lactoferrin is synthesized by activated microglia in the human substantia nigra and its synthesis by the human microglial CHME cell line is upregulated by tumor necrosis factor alpha or 1-methyl-4-phenylpyridinium treatment

1 reference

12 December 2020

In vitro studies of ferritin iron release and neurotoxicity.

1 reference

12 December 2020

Iron deficiency alters dopamine transporter functioning in rat striatum.

1 reference

12 December 2020

1 reference

12 December 2020

Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease.

1 reference

12 December 2020

Mitochondrial ferritin expression in adult mouse tissues

1 reference

12 December 2020

Structural and functional diversity of voltage-activated calcium channels.

1 reference

12 December 2020

Unique iron binding and oxidation properties of human mitochondrial ferritin: a comparative analysis with Human H-chain ferritin

1 reference

12 December 2020

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease

1 reference

12 December 2020

Dopamine release rather than content in the caudate putamen is associated with behavioral changes in the iron rat model of Parkinson's disease

1 reference

12 December 2020

Iron regulatory proteins increase neuronal vulnerability to hydrogen peroxide

1 reference

12 December 2020

The relationship between intracellular free iron and cell injury in cultured neurons, astrocytes, and oligodendrocytes.

1 reference

12 December 2020

Targeting chelatable iron as a therapeutic modality in Parkinson's disease

1 reference

12 December 2020

Sulfonylurea binding sites in normal human brain and in Parkinson's disease, progressive supranuclear palsy and Huntington's disease

1 reference

12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

12 December 2020

Intrapallidal lipopolysaccharide injection increases iron and ferritin levels in glia of the rat substantia nigra and induces locomotor deficits

1 reference

12 December 2020

A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans

1 reference

12 December 2020

Early iron deficiency alters sensorimotor development and brain monoamines in rats.

1 reference

12 December 2020

Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

1 reference

12 December 2020

Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein

1 reference

12 December 2020

Cerebrospinal fluid levels of transition metals in patients with Parkinson's disease

1 reference

12 December 2020

Modulation of iron uptake in heart by L-type Ca2+ channel modifiers: possible implications in iron overload.

1 reference

12 December 2020

Transferrin receptor 2: a new molecule in iron metabolism

1 reference

12 December 2020

Proteasome inhibition modeling nigral neuron degeneration in Parkinson's disease

1 reference

12 December 2020

sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin

1 reference

12 December 2020

Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

1 reference

12 December 2020

Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins.

1 reference

12 December 2020

Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

1 reference

12 December 2020

Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling

1 reference

12 December 2020

The Role of the L-Chain in Ferritin Iron Incorporation

1 reference

12 December 2020

Assessment of cerebral iron content in patients with Parkinson's disease by the susceptibility-weighted MRI.

1 reference

12 December 2020

Perinatal iron and copper deficiencies alter neonatal rat circulating and brain thyroid hormone concentrations

1 reference

12 December 2020

Biology of oligodendrocyte and myelin in the mammalian central nervous system

1 reference

12 December 2020

Brain iron homeostasis and neurodegenerative disease

1 reference

12 December 2020

Neurobehavioral analysis of developmental iron deficiency in rats

1 reference

12 December 2020

Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins

1 reference

12 December 2020

Mitochondrial ferritin attenuates β-amyloid-induced neurotoxicity: reduction in oxidative damage through the Erk/P38 mitogen-activated protein kinase pathways

1 reference

12 December 2020

Intranigral iron injection induces behavioral and biochemical "parkinsonism" in rats

1 reference

12 December 2020

Midbrain iron content in early Parkinson disease: a potential biomarker of disease status

1 reference

12 December 2020

Increased vulnerability to rotenone-induced neurotoxicity in ceruloplasmin-deficient mice

1 reference

12 December 2020

Neonatal iron deficiency results in irreversible changes in dopamine function in rats

1 reference

12 December 2020

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

1 reference

12 December 2020

ATP-sensitive potassium channels in dopaminergic neurons: transducers of mitochondrial dysfunction.

1 reference

12 December 2020

Quantifying brain iron deposition in patients with Parkinson's disease using quantitative susceptibility mapping, R2 and R2.

1 reference

12 December 2020

Green tea polyphenol (-) -epigallocatechin-3-gallate promotes the rapid protein kinase C- and proteasome-mediated degradation of Bad: implications for neuroprotection

1 reference

12 December 2020

Characterizing iron deposition in Parkinson's disease using susceptibility-weighted imaging: an in vivo MR study.

1 reference

12 December 2020

Iron-melanin complex in substantia nigra of parkinsonian brains: an x-ray microanalysis

1 reference

12 December 2020

Iron dysregulation in Huntington's disease

1 reference

12 December 2020

Impact of restless legs syndrome and iron deficiency on attention-deficit/hyperactivity disorder in children

1 reference

12 December 2020

Role of hepcidin in murine brain iron metabolism

1 reference

12 December 2020

A human mitochondrial ferritin encoded by an intronless gene

1 reference

12 December 2020

Lysosomal proteolysis is the primary degradation pathway for cytosolic ferritin and cytosolic ferritin degradation is necessary for iron exit.

1 reference

12 December 2020

The 5'-untranslated region of Parkinson's disease alpha-synuclein messengerRNA contains a predicted iron responsive element

1 reference

12 December 2020

Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein.

1 reference

12 December 2020

Regulation of hepcidin and iron-overload disease

1 reference

12 December 2020

Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators

1 reference

12 December 2020

Substantia nigra hyperechogenicity with LRRK2 G2019S mutations

1 reference

12 December 2020

Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis

1 reference

12 December 2020

The role of iron in brain ageing and neurodegenerative disorders.

1 reference

12 December 2020

Reduced ferroxidase activity in the cerebrospinal fluid from patients with Parkinson's disease

1 reference

12 December 2020

Decreased serum ceruloplasmin levels characteristically aggravate nigral iron deposition in Parkinson's disease.

1 reference

12 December 2020

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

1 reference

12 December 2020

An introduction to the free radical hypothesis in Parkinson's disease

1 reference

12 December 2020

Neuroprotective effects of iron chelator Desferal on dopaminergic neurons in the substantia nigra of rats with iron-overload.

1 reference

12 December 2020

Dietary iron intake and risk of Parkinson's disease

1 reference

12 December 2020

Echogenicity of the substantia nigra: association with increased iron content and marker for susceptibility to nigrostriatal injury

1 reference

12 December 2020

Lower serum ceruloplasmin levels correlate with younger age of onset in Parkinson's disease

1 reference

12 December 2020

Distribution of divalent metal transporter-1 in the monkey basal ganglia

1 reference

12 December 2020

The density of [125I]-transferrin binding sites on perikarya of melanized neurons of the substantia nigra is decreased in Parkinson's disease.

1 reference

12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

12 December 2020

1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide

1 reference

12 December 2020

Heme oxygenase expression in human central nervous system disorders

1 reference

12 December 2020

Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1)

1 reference

12 December 2020

α-Synuclein Over-Expression Induces Increased Iron Accumulation and Redistribution in Iron-Exposed Neurons.

1 reference

12 December 2020

Metals and neuroscience.

1 reference

12 December 2020

Quantitative assessment of iron deposition in the midbrain using 3D-enhanced T2 star weighted angiography (ESWAN): a preliminary cross-sectional study of 20 Parkinson's disease patients.

1 reference

12 December 2020

Nigral iron elevation is an invariable feature of Parkinson's disease and is a sufficient cause of neurodegeneration

1 reference

12 December 2020

Nutritional iron deprivation attenuates kainate-induced neurotoxicity in rats: implications for involvement of iron in neurodegeneration

1 reference

12 December 2020

KATP channels as molecular sensors of cellular metabolism

1 reference

12 December 2020

Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.

1 reference

12 December 2020

Distribution of the iron-regulating protein hepcidin in the murine central nervous system.

1 reference

12 December 2020

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

1 reference

12 December 2020

Glutathione depletion in immortalized midbrain-derived dopaminergic neurons results in increases in the labile iron pool: implications for Parkinson's disease.

1 reference

12 December 2020

Mitochondrial control of cell death

1 reference

12 December 2020

Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson's disease after peripheral administration

1 reference

12 December 2020

Characterization and distribution of ferritin binding sites in the adult mouse brain.

1 reference

12 December 2020

Mouse HFE inhibits Tf-uptake and iron accumulation but induces non-transferrin bound iron (NTBI)-uptake in transformed mouse fibroblasts

1 reference

12 December 2020

Iron trafficking in the mitochondrion: novel pathways revealed by disease.

1 reference

12 December 2020

Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson disease

1 reference

12 December 2020

The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease

1 reference

12 December 2020

Ferritin as a source of iron for oxidative damage

1 reference

12 December 2020

Ceruloplasmin is Involved in the Nigral Iron Accumulation of 6-OHDA-Lesioned Rats.

1 reference

12 December 2020

Neonatal iron exposure induces neurobehavioural dysfunctions in adult mice.

1 reference

12 December 2020

Genetic iron chelation protects against proteasome inhibition-induced dopamine neuron degeneration

1 reference

12 December 2020

Dopamine neurotoxicity: age-dependent behavioral and histological effects

1 reference

12 December 2020

Tim-2 is the receptor for H-ferritin on oligodendrocytes

1 reference

12 December 2020

Molecular mechanisms and regulation of iron transport

1 reference

12 December 2020

Brain iron deficiency and excess; cognitive impairment and neurodegeneration with involvement of striatum and hippocampus

1 reference

12 December 2020

Mechanistic analysis of iron accumulation by endothelial cells of the BBB

1 reference

12 December 2020

1 reference

12 December 2020

Complex I, iron, and ferritin in Parkinson's disease substantia nigra

1 reference

12 December 2020

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

1 reference

12 December 2020

Mining the genome for iron

1 reference

12 December 2020

Glial cells contribute more to iron and aluminum accumulation but are more resistant to oxidative stress than neuronal cells

1 reference

12 December 2020

Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration

1 reference

12 December 2020

Ferroportin 1 but not hephaestin contributes to iron accumulation in a cell model of Parkinson's disease

1 reference

12 December 2020

L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy

1 reference

12 December 2020

A proposed dual role of neuromelanin in the pathogenesis of Parkinson's disease

1 reference

12 December 2020

The Kir6.1-protein, a pore-forming subunit of ATP-sensitive potassium channels, is prominently expressed by giant cholinergic interneurons in the striatum of the rat brain

1 reference

12 December 2020

Role of dietary iron restriction in a mouse model of Parkinson's disease

1 reference

12 December 2020

'Rejuvenation' protects neurons in mouse models of Parkinson's disease

1 reference

12 December 2020

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease.

1 reference

12 December 2020

Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury.

1 reference

12 December 2020

Iron-dependent degradation of apo-IRP1 by the ubiquitin-proteasome pathway

1 reference

12 December 2020

The Parkinson disease-associated A30P mutation stabilizes alpha-synuclein against proteasomal degradation triggered by heme oxygenase-1 over-expression in human neuroblastoma cells.

1 reference

12 December 2020

Identification of L-ferritin in neuromelanin granules of the human substantia nigra: a targeted proteomics approach

1 reference

12 December 2020

Melatonin suppresses iron-induced neurodegeneration in rat brain

1 reference

12 December 2020

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

1 reference

12 December 2020

Time dependent effects of 6-OHDA lesions on iron level and neuronal loss in rat nigrostriatal system

1 reference

12 December 2020

Rg1 protects the MPP+-treated MES23.5 cells via attenuating DMT1 up-regulation and cellular iron uptake

1 reference

12 December 2020

A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease

1 reference

12 December 2020

Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration

1 reference

12 December 2020

High field magnetic resonance microscopy of the human hippocampus in Alzheimer's disease: quantitative imaging and correlation with iron.

1 reference

12 December 2020

Increased DMT1 expression and iron content in MPTP-treated C57BL/6 mice

1 reference

12 December 2020

Downregulation of the human heme oxygenase gene by glucocorticoids and identification of 56b regulatory elements.

1 reference

12 December 2020

Increased iron in the substantia nigra of 6-OHDA induced parkinsonian rats: a nuclear microscopy study.

1 reference

12 December 2020

Does cellular iron dysregulation play a causative role in Parkinson's disease?

1 reference

12 December 2020

Cellular and molecular function of mucolipins (TRPML) and polycystin 2 (TRPP2).

1 reference

12 December 2020

Iron accumulation in the substantia nigra of autosomal recessive juvenile parkinsonism (ARJP)

1 reference

12 December 2020

Increased murine neonatal iron intake results in Parkinson-like neurodegeneration with age.

1 reference

12 December 2020

Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier

1 reference

12 December 2020

Individual dopaminergic neurons show raised iron levels in Parkinson disease.

1 reference

12 December 2020

Dietary fats, cholesterol and iron as risk factors for Parkinson's disease

1 reference

12 December 2020

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

1 reference

12 December 2020

MRI estimates of brain iron concentration in normal aging: comparison of field-dependent (FDRI) and phase (SWI) methods.

1 reference

12 December 2020

Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation

1 reference

12 December 2020

Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alleles.

1 reference

12 December 2020

The influence of dietary status on the cognitive performance of children

1 reference

12 December 2020

CSF iron, ferritin and transferrin levels in restless legs syndrome

1 reference

12 December 2020

Etiologic Classification of Attention-Deficit/Hyperactivity Disorder

1 reference

12 December 2020

Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin

1 reference

12 December 2020

Iron sensing as a partnership: HFE and transferrin receptor 2.

1 reference

12 December 2020

Iron-binding characteristics of neuromelanin of the human substantia nigra.

1 reference

12 December 2020

Alzheimer's disease therapeutics targeted to the control of amyloid precursor protein translation: maintenance of brain iron homeostasis

1 reference

12 December 2020

Cellular distribution of iron in the brain of the Belgrade rat.

1 reference

12 December 2020

Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo

1 reference

12 December 2020

Iron misregulation in the brain: a primary cause of neurodegenerative disorders

1 reference

12 December 2020

Antiviral activities of lactoferrin

1 reference

12 December 2020

Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome

1 reference

12 December 2020

Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria

1 reference

12 December 2020

My love with monoamine oxidase, iron and Parkinson's disease.

1 reference

12 December 2020

Cellular distribution of ferritin subunits in postnatal rat brain.

1 reference

12 December 2020

K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons

1 reference

12 December 2020

Aceruloplasminemia: molecular characterization of this disorder of iron metabolism

1 reference

12 December 2020

Isoform specific regulation of divalent metal (ion) transporter (DMT1) by proteasomal degradation

1 reference

12 December 2020

Proinflammatory cytokines promote glial heme oxygenase-1 expression and mitochondrial iron deposition: implications for multiple sclerosis

1 reference

12 December 2020

Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease

1 reference

12 December 2020

Brain iron uptake and homeostatic mechanisms: an overview

1 reference

12 December 2020

Neuroprotective effects of ginkgetin against neuroinjury in Parkinson's disease model induced by MPTP via chelating iron

1 reference

12 December 2020

Isoforms of ferritin have a specific cellular distribution in the brain.

1 reference

12 December 2020

Transcranial sonography findings in a large family with homozygous and heterozygous PINK1 mutations

1 reference

12 December 2020

Iron protects astrocytes from 6-hydroxydopamine toxicity.

1 reference

12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

12 December 2020

Myricetin reduces 6-hydroxydopamine-induced dopamine neuron degeneration in rats.

1 reference

12 December 2020

Iron and paraquat as synergistic environmental risk factors in sporadic Parkinson's disease accelerate age-related neurodegeneration.

1 reference

12 December 2020

Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease

1 reference

12 December 2020

Metals in our minds: therapeutic implications for neurodegenerative disorders

1 reference

12 December 2020

Distribution of 125I-ferrotransferrin binding sites in the mesencephalon of control subjects and patients with Parkinson's disease.

1 reference

12 December 2020

Microglia and astroglia prevent oxidative stress-induced neuronal cell death: implications for aceruloplasminemia.

1 reference

12 December 2020

Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent

1 reference

12 December 2020

Early and late molecular events in neurodegeneration and neuroprotection in Parkinson's disease MPTP model as assessed by cDNA microarray; the role of iron

1 reference

12 December 2020

Over-expressed human divalent metal transporter 1 is involved in iron accumulation in MES23.5 cells

1 reference

12 December 2020

Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease

1 reference

12 December 2020

Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate.

1 reference

12 December 2020

Hepcidin, a new iron regulatory peptide

1 reference

12 December 2020

Ferritin: a novel mechanism for delivery of iron to the brain and other organs.

1 reference

12 December 2020

Iron, the substantia nigra and related neurological disorders

1 reference

12 December 2020

Developmental, regional, and cellular expression of SFT/UbcH5A and DMT1 mRNA in brain

1 reference

12 December 2020

Mitochondrial involvement in genetically determined transition metal toxicity I. Iron toxicity.

1 reference

12 December 2020

Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1.

1 reference

12 December 2020

Mapping metals in Parkinson's and normal brain using rapid-scanning x-ray fluorescence.

1 reference

12 December 2020

Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

1 reference

12 December 2020

Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease

1 reference

12 December 2020

Brain iron pathways and their relevance to Parkinson's disease.

1 reference

12 December 2020

Clinical MRI for iron detection in Parkinson's disease.

1 reference

12 December 2020

Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel

1 reference

12 December 2020

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

1 reference

12 December 2020

Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat.

1 reference

12 December 2020

Iron regulates cytoplasmic levels of a novel iron-responsive element-binding protein without aconitase activity

1 reference

12 December 2020

TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis

1 reference

12 December 2020

Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy

1 reference

12 December 2020

Neuroprotective mechanism of mitochondrial ferritin on 6-hydroxydopamine-induced dopaminergic cell damage: implication for neuroprotection in Parkinson's disease.

1 reference

12 December 2020

Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons

1 reference

12 December 2020

In vivo detection of iron and neuromelanin by transcranial sonography--a new approach for early detection of substantia nigra damage

1 reference

12 December 2020

Proteome analysis of human substantia nigra in Parkinson's disease.

1 reference

12 December 2020

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

1 reference

12 December 2020

Iron-dependent regulation of the divalent metal ion transporter

1 reference

12 December 2020

Pooled analysis of iron-related genes in Parkinson's disease: association with transferrin

1 reference

12 December 2020

Novel 5' untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for down syndrome and Alzheimer's disease

1 reference

12 December 2020

Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: relationship between pore opening and the activity of mitochondrial phospholipases.

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12 December 2020

Heme and non-heme iron transporters in non-polarized and polarized cells

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12 December 2020

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.

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12 December 2020

Hereditary ceruloplasmin deficiency with hemosiderosis: a clinicopathological study of a Japanese family

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12 December 2020

Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI-ceruloplasmin

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12 December 2020

What have we learnt from CDNA microarray gene expression studies about the role of iron in MPTP induced neurodegeneration and Parkinson's disease?

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12 December 2020

Cellular distribution of the iron-binding protein lactotransferrin in the mesencephalon of Parkinson's disease cases

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12 December 2020

Scara5 is a ferritin receptor mediating non-transferrin iron delivery

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12 December 2020

Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3'-untranslated region: implications in neurodegenerative diseases

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12 December 2020

Peripheral iron dextran induced degeneration of dopaminergic neurons in rat substantia nigra.

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12 December 2020

Parkinson's disease risks associated with dietary iron, manganese, and other nutrient intakes.

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12 December 2020

Age-dependent and iron-independent expression of two mRNA isoforms of divalent metal transporter 1 in rat brain

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12 December 2020

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

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12 December 2020

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

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12 December 2020

Astrocytes and Parkinson's disease

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12 December 2020

Transferrin and transferrin receptor function in brain barrier systems

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12 December 2020

Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

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12 December 2020

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

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12 December 2020

Iron elevations in the aging Parkinsonian brain: a consequence of impaired iron homeostasis?

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12 December 2020

Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

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12 December 2020

The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging

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12 December 2020

Alpha-synuclein is a cellular ferrireductase

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12 December 2020

Mitochondrial mechanisms of estrogen neuroprotection

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12 December 2020

Neuroprotective and neurorestorative activities of a novel iron chelator-brain selective monoamine oxidase-A/monoamine oxidase-B inhibitor in animal models of Parkinson's disease and aging.

1 reference

12 December 2020

Transcranial ultrasound in different monogenetic subtypes of Parkinson's disease.

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12 December 2020

Identification of the ferroxidase centre in ferritin

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12 December 2020

Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2

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12 December 2020

Transient receptor potential cation channels in disease

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12 December 2020

Iron metabolism in Parkinsonian syndromes

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12 December 2020

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

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12 December 2020

Ferroportin1 and hephaestin are involved in the nigral iron accumulation of 6-OHDA-lesioned rats

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12 December 2020

The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy

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12 December 2020

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

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12 December 2020

Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat

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12 December 2020