(Q38822748)

6 September 2017

title

Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future (English)

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6 September 2017

Jeanine Harrigan

1

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6 September 2017

Xavier Jacq

series ordinal

2

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6 September 2017

language of work or name

English

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publication date

1 January 2016

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Methods in Molecular Biology

6 September 2017

published in

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6 September 2017

volume

1449

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6 September 2017

page(s)

395-410

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Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets

6 September 2017

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Dehydroalanine-based diubiquitin activity probes.

21 January 2018

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21 January 2018

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Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes

21 January 2018

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Activity-based diubiquitin probes for elucidating the linkage specificity of deubiquitinating enzymes

21 January 2018

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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

21 January 2018

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Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis

21 January 2018

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The proteasome under the microscope: the regulatory particle in focus

21 January 2018

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Applications of copper-catalyzed click chemistry in activity-based protein profiling.

21 January 2018

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Development of activity-based probes for ubiquitin and ubiquitin-like protein signaling pathways

21 January 2018

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Activity-based imaging probes of the proteasome

21 January 2018

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Endocytosis: the DUB version

21 January 2018

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JAMM: a metalloprotease-like zinc site in the proteasome and signalosome

21 January 2018

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COP9 signalosome function in the DDR.

21 January 2018

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Fluorescence-based active site probes for profiling deubiquitinating enzymes

21 January 2018

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Small-Molecule Inhibitors and Probes for Ubiquitin- and Ubiquitin-Like-Specific Proteases

21 January 2018

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Chemical synthesis of phosphorylated ubiquitin and diubiquitin exposes positional sensitivities of e1-e2 enzymes and deubiquitinases

21 January 2018

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12 December 2020

Proteolysis: from the lysosome to ubiquitin and the proteasome

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12 December 2020

Structural basis of ubiquitin recognition by the deubiquitinating protease USP2

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12 December 2020

Ubiquitin is phosphorylated by PINK1 to activate parkin

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12 December 2020

Complete subunit architecture of the proteasome regulatory particle

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12 December 2020

DUBs, the regulation of cell identity and disease

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12 December 2020

Mechanism-based proteomics tools based on ubiquitin and ubiquitin-like proteins: crystallography, activity profiling, and protease identification

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12 December 2020

Ubiquitin-based anticancer therapy: carpet bombing with proteasome inhibitors vs surgical strikes with E1, E2, E3, or DUB inhibitors

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12 December 2020

Glycine Fluoromethylketones as SENP-Specific Activity Based Probes

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12 December 2020

Chemical synthesis of ubiquitinated peptides with varying lengths and types of ubiquitin chains to explore the activity of deubiquitinases

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12 December 2020

Total chemical synthesis of a 304 amino acid K48-linked tetraubiquitin protein

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12 December 2020

10.1007/978-1-4939-3756-1_26

Identifiers

DOI

1 reference

6 September 2017

0 references

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