(Q38896928)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

review article

1 reference

title

The genome editing revolution: A CRISPR-Cas TALE off-target story (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

author name string

Guillermo Montoya

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

language of work or name

English

0 references

publication date

1 July 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

volume

38 Suppl 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

page(s)

S4-S13

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

Genome engineering with targetable nucleases

18 March 2020

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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

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Nucleases and helicases take center stage in homologous recombination

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Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

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Is non-homologous end-joining really an inherently error-prone process?

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

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Enhancing Gene Targeting with Designed Zinc Finger Nucleases

21 January 2018

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Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

21 January 2018

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Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

21 January 2018

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Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification

21 January 2018

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Design and selection of novel Cys2His2 zinc finger proteins

21 January 2018

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DNA recognition by Cys2His2 zinc finger proteins

21 January 2018

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Engineered I-CreI derivatives cleaving sequences from the human XPC gene can induce highly efficient gene correction in mammalian cells

21 January 2018

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CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

21 January 2018

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Embryo editing sparks epic debate.

21 January 2018

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Don’t edit the human germ line

21 January 2018

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Biotechnology. A prudent path forward for genomic engineering and germline gene modification

21 January 2018

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21 January 2018

CRISPR, the disruptor

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Xanthomonas AvrBs3 family-type III effectors: discovery and function

21 January 2018

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The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

21 January 2018

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Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

21 January 2018

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Structure of the AvrBs3–DNA complex provides new insights into the initial thymine-recognition mechanism

21 January 2018

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Breaking the code of DNA binding specificity of TAL-type III effectors

21 January 2018

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A simple cipher governs DNA recognition by TAL effectors

21 January 2018

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Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers

21 January 2018

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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

21 January 2018

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A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes

21 January 2018

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FLASH assembly of TALENs for high-throughput genome editing

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201670903

Optimization of scarless human stem cell genome editing

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201670903

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

21 January 2018

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BurrH: a new modular DNA binding protein for genome engineering.

21 January 2018

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TAL effector specificity for base 0 of the DNA target is altered in a complex, effector- and assay-dependent manner by substitutions for the tryptophan in cryptic repeat -1.

21 January 2018

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Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues

21 January 2018

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BuD, a helix-loop-helix DNA-binding domain for genome modification

21 January 2018

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TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

21 January 2018

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Targeting DNA double-strand breaks with TAL effector nucleases

21 January 2018

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Compact designer TALENs for efficient genome engineering

21 January 2018

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Creating a monomeric endonuclease TALE-I-SceI with high specificity and low genotoxicity in human cells

21 January 2018

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The I-TevI nuclease and linker domains contribute to the specificity of monomeric TALENs

21 January 2018

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A TALE nuclease architecture for efficient genome editing

21 January 2018

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Chimeric TALE recombinases with programmable DNA sequence specificity

21 January 2018

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Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements

21 January 2018

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The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats

21 January 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

21 January 2018

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The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli

21 January 2018

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Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

21 January 2018

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Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

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RNA-guided editing of bacterial genomes using CRISPR-Cas systems

21 January 2018

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

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CRISPR RNA-guided activation of endogenous human genes

21 January 2018

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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

21 January 2018

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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

21 January 2018

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RNA-guided gene activation by CRISPR-Cas9-based transcription factors

21 January 2018

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Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system

21 January 2018

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

21 January 2018

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Expanding the Biologist's Toolkit with CRISPR-Cas9

21 January 2018

1 reference

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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

21 January 2018

1 reference

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Genome editing technologies: defining a path to clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

DNA targeting specificity of RNA-guided Cas9 nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

A library of TAL effector nucleases spanning the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

An unbiased genome-wide analysis of zinc-finger nuclease specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Determining the specificities of TALENs, Cas9, and other genome-editing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

A TAL effector repeat architecture for frameshift binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Playing the end game: DNA double-strand break repair pathway choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

High frequency targeted mutagenesis using engineered endonucleases and DNA-end processing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Locus-specific editing of histone modifications at endogenous enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Mapping the precision of genome editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

TALEN-based gene correction for epidermolysis bullosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Genome editing at the crossroads of delivery, specificity, and fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201670903

21 January 2018

Identifiers

DOI

10.1002/BIES.201670903

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27417121%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference