(Q38936873)

7 September 2017

Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance (English)

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Christiane Richter-Landsberg

7 September 2017

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series ordinal

4

object named as

Christiane Richter-Landsberg

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7 September 2017

1

Janina Leyk

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7 September 2017

2

Olaf Goldbaum

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7 September 2017

Monika Noack

3

1 reference

7 September 2017

2 December 2014

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Journal of Molecular Neuroscience

7 September 2017

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7 September 2017

55

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7 September 2017

4

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7 September 2017

1031-1046

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https://scigraph.springernature.com/pub.10.1007/s12031-014-0460-y

7 September 2017

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cites work

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Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A

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The acetylation of tau inhibits its function and promotes pathological tau aggregation

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Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

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HDAC6 at the Intersection of Neuroprotection and Neurodegeneration.

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Histone deacetylase 6 interacts with the microtubule-associated protein tau

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Aggregopathy in neurodegenerative diseases: mechanisms and therapeutic implication

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Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

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Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

21 January 2018

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Proteolytic stress causes heat shock protein induction, tau ubiquitination, and the recruitment of ubiquitin to tau-positive aggregates in oligodendrocytes in culture.

21 January 2018

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Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes.

21 January 2018

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The small heat shock protein HSP25 protects astrocytes against stress induced by proteasomal inhibition

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Regulation mechanisms and signaling pathways of autophagy

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Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

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Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

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Aggresomes, inclusion bodies and protein aggregation

21 January 2018

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HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

21 January 2018

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In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

21 January 2018

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HDAC6 a new cellular stress surveillance factor.

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21 January 2018

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Acetylation of tau inhibits its degradation and contributes to tauopathy

21 January 2018

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HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes

21 January 2018

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

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21 January 2018

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Tau-inclusion body formation in oligodendroglia: the role of stress proteins and proteasome inhibition

21 January 2018

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Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration

21 January 2018

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Mode of cell injury and death after hydrogen peroxide exposure in cultured oligodendroglia cells.

21 January 2018

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Characterization of cloned cDNA representing rat myelin basic protein: Absence of expression in brain of shiverer mutant mice

21 January 2018

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Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology

21 January 2018

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Involvement of macroautophagy in multiple system atrophy and protein aggregate formation in oligodendrocytes

21 January 2018

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Inhibition of protein deubiquitination by PR-619 activates the autophagic pathway in OLN-t40 oligodendroglial cells

21 January 2018

1 reference

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Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

21 January 2018

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Autophagic pathways in Parkinson disease and related disorders

21 January 2018

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Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0460-Y

Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions

21 January 2018

1 reference

12 December 2020

Tolerance controls encephalitogenicity of alphaB-crystallin in the Lewis rat

1 reference

12 December 2020

Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes

1 reference

12 December 2020

Proteasome Inhibition Stabilizes Tau Inclusions in Oligodendroglial Cells that Occur after Treatment with Okadaic Acid

1 reference

12 December 2020

Developmental regulation of alternatively spliced isoforms of mRNA encoding MAP2 and tau in rat brain oligodendrocytes during culture maturation.

1 reference

12 December 2020

OLN-93: a new permanent oligodendroglia cell line derived from primary rat brain glial cultures

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12 December 2020

A Simple, Versatile, Sensitive and Volume-Independent Method for Quantitative Protein Determination which is Independent of Other External Influences

1 reference

12 December 2020

10.1007/S12031-014-0460-Y

Identifiers

DOI

1 reference

PubMed ID

25434725

Dimensions Publication ID

7 September 2017

0 references

1 reference

PubMed ID

25434725