(Q38943638)

7 September 2017

Loss of mitofusin 2 links beta-amyloid-mediated mitochondrial fragmentation and Cdk5-induced oxidative stress in neuron cells (English)

1 reference

7 September 2017

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Junghyung Park

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Hoonsung Choi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Ju-Sik Min

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Bokyung Kim

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Sang-Rae Lee

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Myung-Sook Choi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Kyu-Tae Chang

8

1 reference

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7 June 2020

Dong-Seok Lee

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

13 January 2015

1 reference

Journal of Neurochemistry

7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

132

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

6

1 reference

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7 June 2020

page(s)

687-702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy

7 June 2020

cites work

1 reference

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

21 January 2018

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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

21 January 2018

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Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death

21 January 2018

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Physiological functions of mitochondrial fusion

21 January 2018

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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria

21 January 2018

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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

21 January 2018

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Mitochondrial fusion protects against neurodegeneration in the cerebellum.

21 January 2018

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Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

21 January 2018

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Role of mitofusin 2 (Mfn2) in controlling cellular proliferation

21 January 2018

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Mitochondrial dynamics in cell death and neurodegeneration

21 January 2018

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

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Synaptic mitochondrial pathology in Alzheimer's disease

21 January 2018

1 reference

Why size matters - balancing mitochondrial dynamics in Alzheimer's disease

21 January 2018

1 reference

Cdk5 phosphorylates a component of the HDAC complex and regulates histone acetylation during neuronal cell death.

21 January 2018

1 reference

Mitofusin-2 ameliorates high-fat diet-induced insulin resistance in liver of rats

21 January 2018

1 reference

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

21 January 2018

1 reference

Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

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Characterization of neural cell types expressing peroxiredoxins in mouse brain.

21 January 2018

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2-Cys peroxiredoxin function in intracellular signal transduction: therapeutic implications

21 January 2018

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Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage.

21 January 2018

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Mitochondrial fragmentation in neurodegeneration

21 January 2018

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Intracellular amyloid-beta in Alzheimer's disease

21 January 2018

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Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons.

21 January 2018

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A brain-specific activator of cyclin-dependent kinase 5.

21 January 2018

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

21 January 2018

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Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway.

21 January 2018

1 reference

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

1 reference

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

21 January 2018

1 reference

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

21 January 2018

1 reference

Loss of mitofusin 2 promotes endoplasmic reticulum stress

21 January 2018

1 reference

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

21 January 2018

1 reference

Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells.

21 January 2018

1 reference

Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF.

21 January 2018

1 reference

Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit

21 January 2018

1 reference

Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo

21 January 2018

1 reference

Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease.

21 January 2018

1 reference

21 January 2018

1 reference

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

21 January 2018

1 reference

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

21 January 2018

1 reference

Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics

21 January 2018

1 reference

Controlled elimination of intracellular H(2)O(2): regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification

21 January 2018

1 reference

Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells

21 January 2018

1 reference

Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.

21 January 2018

1 reference

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

21 January 2018

1 reference

Swedish mutation within amyloid precursor protein modulates global gene expression towards the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

A truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice

21 January 2018

1 reference

Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction.

21 January 2018

1 reference

Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimer's disease

21 January 2018

1 reference

Cdk5 is essential for synaptic vesicle endocytosis

21 January 2018

1 reference

An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator

21 January 2018

1 reference

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

21 January 2018

1 reference

A beta oligomers - a decade of discovery

21 January 2018

1 reference

Cyclin-dependent kinase-5 prevents neuronal apoptosis through ERK-mediated upregulation of Bcl-2.

21 January 2018

1 reference

Endogenous overproduction of beta-amyloid induces tau hyperphosphorylation and decreases the solubility of tau in N2a cells

21 January 2018

1 reference

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

21 January 2018

1 reference

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

21 January 2018

1 reference

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

21 January 2018

1 reference

Inhibition of CDK5 is protective in necrotic and apoptotic paradigms of neuronal cell death and prevents mitochondrial dysfunction

21 January 2018

1 reference

Mitochondrial fusion and fission in cell life and death

21 January 2018

1 reference

Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins

21 January 2018

1 reference

Rapid cell death is preceded by amyloid plaque-mediated oxidative stress

21 January 2018

1 reference

Amyloid precursor protein, heat-shock proteins, and Bcl-2 form a complex in mitochondria and modulate mitochondria function and apoptosis in N2a cells.

21 January 2018

1 reference

High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission

21 January 2018

1 reference

The antioxidant enzyme peroxiredoxin and its protective role in neurological disorders

21 January 2018

1 reference

Histone decacetylase inhibitors prevent mitochondrial fragmentation and elicit early neuroprotection against MPP+.

21 January 2018

1 reference

Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis

21 January 2018

1 reference