(Q38970553)

8 September 2017

1 reference

title

Nrf2-a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke (English)

1 reference

8 September 2017

Rongrong Zhang

1

1 reference

8 September 2017

Mengxue Xu

2

1 reference

8 September 2017

Yu Wang

3

1 reference

8 September 2017

Fei Xie

4

1 reference

8 September 2017

Gang Zhang

5

1 reference

8 September 2017

Xinyue Qin

6

1 reference

8 September 2017

30 September 2016

1 reference

8 September 2017

Molecular Neurobiology

1 reference

https://scigraph.springernature.com/pub.10.1007/s12035-016-0111-0

8 September 2017

0 references

cites work

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The role of free radical generation in increasing cerebrovascular permeability

21 January 2018

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Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress

21 January 2018

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NADPH oxidases as therapeutic targets in ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The use of microRNAs to modulate redox and immune response to stroke

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Reactive oxygen radicals in signaling and damage in the ischemic brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Regulation of Nrf2-an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The role of Nrf2 in oxidative stress-induced endothelial injuries

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The role of Nrf2-mediated pathway in cardiac remodeling and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Resveratrol Preconditioning Protects Against Cerebral Ischemic Injury via Nuclear Erythroid 2-Related Factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Dimethyl fumarate attenuates cerebral edema formation by protecting the blood-brain barrier integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

S-allyl cysteine activates the Nrf2-dependent antioxidant response and protects neurons against ischemic injury in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Neuroprotection by acetyl-11-keto-β-Boswellic acid, in ischemic brain injury involves the Nrf2/HO-1 defense pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

NRF2-regulation in brain health and disease: implication of cerebral inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Role of Nrf2 in protection against acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Oxidative stress response and Nrf2 signaling in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The glutathione system: a new drug target in neuroimmune disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Oxidative stress responses and NRF2 in human leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Cysteine-based regulation of the CUL3 adaptor protein Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Procyanidin B2 induces Nrf2 translocation and glutathione S-transferase P1 expression via ERKs and p38-MAPK pathways and protect human colonic cells against oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Identification of novel microRNAs in post-transcriptional control of Nrf2 expression and redox homeostasis in neuronal, SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Activated microglia decrease histone acetylation and Nrf2-inducible anti-oxidant defence in astrocytes: restoring effects of inhibitors of HDACs, p38 MAPK and GSK3β

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Reactive oxygen species and ischemic cerebrovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Reactive oxygen species and the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Mitochondrial respiratory chain and free radical generation in stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Sites of generation of reactive oxygen species in homogenates of brain tissue determined with the use of respiratory substrates and inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Characterization of superoxide-producing sites in isolated brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Which NADPH oxidase isoform is relevant for ischemic stroke? The case for nox 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Involvement of ROS in BBB dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

NADPH Oxidase: A Potential Target for Treatment of Stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Mammalian xanthine oxidoreductase - mechanism of transition from xanthine dehydrogenase to xanthine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species-studies in white blood cells and in animal models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

HIF-1α activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Overexpression of Fibulin-5 Attenuates Ischemia/Reperfusion Injury After Middle Cerebral Artery Occlusion in Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Posttreatment with 11-Keto-β-Boswellic Acid Ameliorates Cerebral Ischemia-Reperfusion Injury: Nrf2/HO-1 Pathway as a Potential Mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Osthole, a natural coumarin improves cognitive impairments and BBB dysfunction after transient global brain ischemia in C57 BL/6J mice: involvement of Nrf2 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Neurotoxicological mechanism of methylmercury induced by low-dose and long-term exposure in mice: oxidative stress and down-regulated Na+/K(+)-ATPase involved.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Protective effects of tirilazad mesylate and metabolite U-89678 against blood-brain barrier damage after subarachnoid hemorrhage and lipid peroxidative neuronal injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Hydrogen peroxide-induced alterations of tight junction proteins in bovine brain microvascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

NADPH oxidase-mediated redox signal contributes to lipoteichoic acid-induced MMP-9 upregulation in brain astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Salusin-β Promotes Vascular Smooth Muscle Cell Migration and Intimal Hyperplasia After Vascular Injury via ROS/NFκB/MMP-9 Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Redox control of microglial function: molecular mechanisms and functional significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

NOD2 is involved in the inflammatory response after cerebral ischemia-reperfusion injury and triggers NADPH oxidase 2-derived reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Protection by genistein on cortical neurons against oxidative stress injury via inhibition of NF-kappaB, JNK and ERK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Pre-treatment with the synthetic antioxidant T-butyl bisphenol protects cerebral tissues from experimental ischemia reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Alterations of oxidative stress markers and apoptosis markers in the striatum after transient focal cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Reactive oxygen species, cellular redox systems, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Roles of nitric oxide in brain hypoxia-ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

ICAM-1-coupled cytoskeletal rearrangements and transendothelial lymphocyte migration involve intracellular calcium signaling in brain endothelial cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

17β-Estradiol Ameliorates Tight Junction Disruption via Repression of MMP Transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

RhoA and NF-κB are involved in lipopolysaccharide-induced brain microvascular cell line hyperpermeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Nrf2 expression by neurons, astroglia, and microglia in the cerebral cortical penumbra of ischemic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Temporal and spatial distribution of Nrf2 in rat brain following stroke: quantification of nuclear to cytoplasmic Nrf2 content using a novel immunohistochemical technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Tetramethylpyrazine inhibits neutrophil activation following permanent cerebral ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Peroxynitrite formation in focal cerebral ischemia-reperfusion in rats occurs predominantly in the peri-infarct region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Nrf2 and NF-κB and Their Concerted Modulation in Cancer Pathogenesis and Progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Sevoflurane postconditioning attenuates cerebral ischemia-reperfusion injury via protein kinase B/nuclear factor-erythroid 2-related factor 2 pathway activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Procyanidin B2 attenuates neurological deficits and blood-brain barrier disruption in a rat model of cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Oral administration of glutathione improves memory deficits following transient brain ischemia by reducing brain oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Glutathione monoethylester prevents mitochondrial glutathione depletion during focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

The protection by octreotide against experimental ischemic stroke: up-regulated transcription factor Nrf2, HO-1 and down-regulated NF-κB expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Oral administration of the flavanol (-)-epicatechin bolsters endogenous protection against focal ischemia through the Nrf2 cytoprotective pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

(-)-Epigallocatechin gallate protects against cerebral ischemia-induced oxidative stress via Nrf2/ARE signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

(S)-ZJM-289 preconditioning induces a late phase protection against nervous injury induced by transient cerebral ischemia and oxygen-glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Neuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Docosahexaenoic acid reduces cellular inflammatory response following permanent focal cerebral ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Preconditioning with Ginkgo biloba (EGb 761®) provides neuroprotection through HO1 and CRMP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Eriodictyol-7-O- glucoside activates Nrf2 and protects against cerebral ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Gastrodin alleviates cerebral ischemic damage in mice by improving anti-oxidant and anti-inflammation activities and inhibiting apoptosis pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Lipoxin A4 ameliorates cerebral ischaemia/reperfusion injury through upregulation of nuclear factor erythroid 2-related factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia-reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

p-Hydroxybenzyl alcohol prevents brain injury and behavioral impairment by activating Nrf2, PDI, and neurotrophic factor genes in a rat model of brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Paeonol pretreatment attenuates cerebral ischemic injury via upregulating expression of pAkt, Nrf2, HO-1 and ameliorating BBB permeability in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Erythropoietin activates Keap1-Nrf2/ARE pathway in rat brain after ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Resveratrol pretreatment attenuates cerebral ischemic injury by upregulating expression of transcription factor Nrf2 and HO-1 in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Totarol prevents neuronal injury in vitro and ameliorates brain ischemic stroke: Potential roles of Akt activation and HO-1 induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Sequential Upregulation of Superoxide Dismutase 2 and Heme Oxygenase 1 by tert-Butylhydroquinone Protects Mitochondria during Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Low doses of carbon monoxide protect against experimental focal brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial K(ATP) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Efficacy of prophylactic flavan-3-ol in permanent focal ischemia in 12-mo-old mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-0111-0

Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo

21 January 2018

1 reference

12 December 2020

Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia

1 reference

12 December 2020

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

1 reference

12 December 2020

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

1 reference

12 December 2020

Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2

1 reference

12 December 2020

Heme oxygenase: colors of defense against cellular stress

1 reference

12 December 2020

Expression of Keap1-Nrf2 system and antioxidative proteins in mouse brain after transient middle cerebral artery occlusion

1 reference

12 December 2020

Time course of nitric oxide synthase activity in neuronal, glial, and endothelial cells of rat striatum following focal cerebral ischemia

1 reference

12 December 2020

PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells

1 reference

12 December 2020

Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells

1 reference

12 December 2020

Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion.

1 reference

12 December 2020

Induction of oxidative DNA damage in the peri-infarct region after permanent focal cerebral ischemia

1 reference

12 December 2020

The neuroprotection of oxymatrine in cerebral ischemia/reperfusion is related to nuclear factor erythroid 2-related factor 2 (nrf2)-mediated antioxidant response: role of nrf2 and hemeoxygenase-1 expression

1 reference

12 December 2020

10.1007/S12035-016-0111-0

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1 reference