(Q38983810)

English

The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation (English)

1 reference

Europe PubMed Central

8 September 2017

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

6

object named as

Nullin Divecha

1 reference

Europe PubMed Central

8 September 2017

1

object named as

David R Jones

1 reference

Europe PubMed Central

8 September 2017

author name string

Willem-Jan Keune

2

1 reference

Europe PubMed Central

8 September 2017

Karen E Anderson

3

1 reference

Europe PubMed Central

8 September 2017

Len R Stephens

4

1 reference

Europe PubMed Central

8 September 2017

Phillip T Hawkins

5

1 reference

Europe PubMed Central

8 September 2017

language of work or name

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publication date

14 July 2014

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

281

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Europe PubMed Central

8 September 2017

16

1 reference

Europe PubMed Central

8 September 2017

3591-3608

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Europe PubMed Central

8 September 2017

The engine driving the ship: metabolic steering of cell proliferation and death.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

AMP-activated protein kinase: new regulation, new roles?

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Ras, PI(3)K and mTOR signalling controls tumour cell growth

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

The LKB1 tumor suppressor negatively regulates mTOR signaling

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Cellular metabolic stress: considering how cells respond to nutrient excess.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Metabolic pathway alterations that support cell proliferation.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Targeting cancer metabolism: a therapeutic window opens

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Otto Warburg's contributions to current concepts of cancer metabolism

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

On the Origin of Cancer Cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

The Cellular Fate of Glucose and Its Relevance in Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Hexosamines, insulin resistance, and the complications of diabetes: current status

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Metabolism, cell surface organization, and disease

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Adaptive regulation at the cell surface by N-glycosylation.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

O-GlcNAc signalling: implications for cancer cell biology

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Signalling by insulin and IGF receptors: supporting acts and new players

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Tumours with PI3K activation are resistant to dietary restriction

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Insulin and IGF-I signaling through the insulin receptor substrate 1.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

PDK1, one of the missing links in insulin signal transduction?

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

O-GlcNAc protein modification in cancer cells increases in response to glucose deprivation through glycogen degradation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Inhibition of glycogen phosphorylase (GP) by CP-91,149 induces growth inhibition correlating with brain GP expression

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Elevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin Resistance

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Protein O-GlcNAcylation regulates Drosophila growth through the insulin signaling pathway.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Metabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12879

21 January 2018

Identifiers

10.1111/FEBS.12879

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

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