(Q39014909)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634145%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain (English)

1 reference

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10 March 2020

0 references

8

1 reference

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10 March 2020

Terence Y Pang

3

1 reference

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10 March 2020

Catriona A. McLean

4

1 reference

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10 March 2020

Jeffrey R Liddell

5

1 reference

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10 March 2020

Anthony J Hannan

9

1 reference

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10 March 2020

Peter J. Crouch

10

1 reference

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10 March 2020

author name string

Nastasia K H Lim

1

1 reference

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10 March 2020

Lin W Hung

2

1 reference

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10 March 2020

James B Hilton

6

1 reference

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10 March 2020

Qiao-Xin Li

7

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10 March 2020

publication date

14 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634145%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

published in

Human Molecular Genetics

1 reference

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10 March 2020

volume

23

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10 March 2020

issue

15

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10 March 2020

page(s)

4051-4063

1 reference

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A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length.

10 March 2020

cites work

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Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

21 January 2018

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Glycogen synthase kinase-3: properties, functions, and regulation

21 January 2018

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Dysregulation of glycogen synthase kinase-3 in skeletal muscle and the etiology of insulin resistance and type 2 diabetes

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Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy

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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

21 January 2018

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A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health

21 January 2018

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Energy dysfunction in Huntington's disease: insights from PGC-1α, AMPK, and CKB.

21 January 2018

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Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells

21 January 2018

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Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease

21 January 2018

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A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.

21 January 2018

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Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

21 January 2018

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Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences

21 January 2018

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N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking

21 January 2018

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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

21 January 2018

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Effects of overexpression of huntingtin proteins on mitochondrial integrity

21 January 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

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Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation.

21 January 2018

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Early alterations of brain cellular energy homeostasis in Huntington disease models

21 January 2018

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Functional imaging in Huntington's disease

21 January 2018

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Positron emission tomography in the early diagnosis of Huntington's disease

21 January 2018

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Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease

21 January 2018

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18F-FDG PET uptake in the pre-Huntington disease caudate affects the time-to-onset independently of CAG expansion size

21 January 2018

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Decreased Metabolism in the Cerebral Cortex in Early-Stage Huntington's Disease: A Possible Biomarker of Disease Progression?

21 January 2018

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Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease.

21 January 2018

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Shaping the role of mitochondria in the pathogenesis of Huntington's disease

21 January 2018

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Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease

21 January 2018

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

21 January 2018

1 reference

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A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

21 January 2018

1 reference

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Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

21 January 2018

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Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

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Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

21 January 2018

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Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation

21 January 2018

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Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease

21 January 2018

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Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

21 January 2018

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Applications of the Morris water maze in the study of learning and memory

21 January 2018

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Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease

21 January 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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21 January 2018

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21 January 2018

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Role of CRMP-2 in neuronal polarity.

21 January 2018

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Collapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status

21 January 2018

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21 January 2018

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21 January 2018

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Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders

21 January 2018

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An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels

21 January 2018

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Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2.

21 January 2018

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