(Q39026969)

8 September 2017

1 reference

title

A comprehensive map of molecular drug targets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

John P. Overington

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

Rita Santos

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

Anne Hersey

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

10

Tudor I Oprea

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

6

Cristian G Bologa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

author name string

Oleg Ursu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

A Patrícia Bento

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

Ramesh S Donadi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

Anneli Karlsson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

Bissan Al-Lazikani

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

publication date

2 December 2016

1 reference

Nature Reviews Drug Discovery

8 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

page(s)

19-34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrd.2016.230

13 May 2020

exact match

0 references

cites work

The Nobel chronicles. 1988: James Whyte Black, (b 1924), Gertrude Elion (1918-99), and George H Hitchings (1905-98).

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Genomic sciences and the medicine of tomorrow

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Drugs, their targets and the nature and number of drug targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

How many drug targets are there?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

TTD: Therapeutic Target Database

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

DrugBank: a comprehensive resource for in silico drug discovery and exploration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

SuperTarget and Matador: resources for exploring drug-target relationships

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Trends in the exploitation of novel drug targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

A forensic analysis of drug targets from 2000 through 2012

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Novelty in the target landscape of the pharmaceutical industry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

DrugCentral: online drug compendium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

canSAR: an updated cancer research and drug discovery knowledgebase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

The ChEMBL bioactivity database: an update

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Pimavanserin for the treatment of Parkinson's disease psychosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Differential effects of aripiprazole on D(2), 5-HT(2), and 5-HT(1A) receptor occupancy in patients with schizophrenia: a triple tracer PET study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

The dopamine stabilizer (-)-OSU6162 occupies a subpopulation of striatal dopamine D2/D3 receptors: an [(11)C]raclopride PET study in healthy human subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Expression of muscarinic receptors by human macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

The role of pirenzepine-sensitive (M1) muscarinic receptors in vagally mediated bronchoconstriction in humans.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Penicillin-binding proteins 2x and 2b as primary PBP targets in Streptococcus pneumoniae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Molecular biology of the MEN2 gene.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Use-dependent inhibition of hHCN4 by ivabradine and relationship with reduction in pacemaker activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Dronedarone's inhibition of If current is the primary mechanism responsible for its bradycardic effect

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Identification of the molecular site of ivabradine binding to HCN4 channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Ligand-targeted therapeutics in anticancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

International network of cancer genome projects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Mutational landscape and significance across 12 major cancer types

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

31 March 2020

Cancer genome landscapes

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Discovery and saturation analysis of cancer genes across 21 tumour types

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

31 March 2020

Drugging cancer genomes

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

ABC transporters in cancer: more than just drug efflux pumps.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Objective assessment of cancer genes for drug discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Principles of cancer therapy: oncogene and non-oncogene addiction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

The discovery of first-in-class drugs: origins and evolution.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

How were new medicines discovered?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Unpicking the combination lock for mutant BRAF and RAS melanomas.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Blocking the survival of the nastiest by HSP90 inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Global mapping of pharmacological space

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Prodrugs--from serendipity to rational design.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Ensembl BioMarts: a hub for data retrieval across taxonomic space

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

InParanoid 8: orthology analysis between 273 proteomes, mostly eukaryotic

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Probing the links between in vitro potency, ADMET and physicochemical parameters.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Circos: an information aesthetic for comparative genomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.230

Prioritizing the human genome: knowledge management for drug discovery.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27910877

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of innovation in drug development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27910877

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRD.2016.230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

Dimensions Publication ID

13 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6314433&resulttype=core&format=json

13 May 2020

1 reference