(Q39228542)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23228967%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation (English)

1 reference

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20 February 2020

1 reference

6

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20 February 2020

Tao Liu

9

1 reference

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20 February 2020

Michelle Haber

10

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20 February 2020

Richard B Lock

12

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20 February 2020

author name string

A Malyukova

1

1 reference

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20 February 2020

S Brown

2

1 reference

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20 February 2020

R Papa

3

1 reference

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20 February 2020

R O'Brien

4

1 reference

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20 February 2020

J Giles

5

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20 February 2020

L Dalla Pozza

7

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20 February 2020

R Sutton

8

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20 February 2020

M D Norris

11

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20 February 2020

O Sangfelt

13

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20 February 2020

G M Marshall

14

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20 February 2020

publication date

11 December 2012

1 reference

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20 February 2020

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20 February 2020

volume

27

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20 February 2020

issue

5

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20 February 2020

page(s)

1053-1062

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The Fbxw7/hCdc4 tumor suppressor in human cancer

20 February 2020

cites work

1 reference

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NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study

21 January 2018

1 reference

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Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/FBXW7 mutations, but not of low ERG/BAALC expression: a GRAALL study.

21 January 2018

1 reference

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Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

21 January 2018

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NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951.

21 January 2018

1 reference

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The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function

21 January 2018

1 reference

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The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.

21 January 2018

1 reference

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FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma

21 January 2018

1 reference

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NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

21 January 2018

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Treatment of adult acute lymphoblastic leukemia (ALL): long-term follow-up of the GIMEMA ALL 0288 randomized study

21 January 2018

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Immunophenotypic cell lineage and in vitro cellular drug resistance in childhood relapsed acute lymphoblastic leukaemia

21 January 2018

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Recent insights into the mechanism of glucocorticosteroid-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.361

The glucocorticoid receptor: coding a diversity of proteins and responses through a single gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies

21 January 2018

1 reference

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Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor.

21 January 2018

1 reference

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Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.

21 January 2018

1 reference

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Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Glycogen synthase kinase 3beta-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Fbw7/hCDC4 dimerization regulates its substrate interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

A conceptual view on glucocorticoid-lnduced apoptosis, cell cycle arrest and glucocorticoid resistance in lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Glucocorticoid resistance in thymocytes from mice expressing a T cell receptor transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Gene expression profile of human lymphoid CEM cells sensitive and resistant to glucocorticoid-evoked apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Pro-apoptotic protein BIM in apoptosis of glucocorticoid-sensitive and -resistant acute lymphoblastic leukemia CEM cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Glycogen synthase kinase-3 plays a central role in mediating glucocorticoid-induced apoptosis

21 January 2018

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JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Bim is a suppressor of Myc-induced mouse B cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

inferred from DOI database lookup

7 January 2021

based on heuristic

Hormone-induced nucleosome positioning in the MMTV promoter is reversible

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

inferred from DOI database lookup

7 January 2021

based on heuristic

Opposing functions of Fbxw7 in keratinocyte growth, differentiation and skin tumorigenesis mediated through negative regulation of c-Myc and Notch

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.361

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2012.361

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23228967%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference