(Q39351465)

English

High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery.

scientific article published on June 2012

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31 January 2020

High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery (English)

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14 May 2020

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based on heuristic

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William A Weiss

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14 May 2020

Graeme Eisenhofer

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Graeme Eisenhofer

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14 May 2020

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Jimmy K Stauffer

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14 May 2020

Rimas J Orentas

2

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14 May 2020

Erin Lincoln

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14 May 2020

Tahira Khan

4

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14 May 2020

Rosalba Salcedo

5

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14 May 2020

Julie A Hixon

6

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14 May 2020

Timothy C Back

7

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14 May 2020

Jun S Wei

8

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14 May 2020

Young Song

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14 May 2020

Laura Hurd

11

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14 May 2020

Maria Tsokos

12

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14 May 2020

Edwin W Lai

13

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14 May 2020

Javed Khan

16

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14 May 2020

Jon M Wigginton

17

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14 May 2020

publication date

1 June 2012

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31 January 2020

Cancer Investigation

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14 May 2020

30

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14 May 2020

5

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14 May 2020

343-363

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14 May 2020

Neuroblastoma: biological insights into a clinical enigma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Neuroblastoma: evolving therapies for a disease with many faces

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Advances in the diagnosis and treatment of neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Targeted interleukin-2 therapy for spontaneous neuroblastoma metastases to bone marrow

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Metastasis of C1300 and TBJ murine neuroblastomas correlates with expression of matrix metalloproteinases.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Interleukin-12 transduced dendritic cells induce regression of established murine neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

'Green mice' as a source of ubiquitous green cells.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Therapeutic modulation of Akt activity and antitumor efficacy of interleukin-12 against orthotopic murine neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

IL-27 mediates complete regression of orthotopic primary and metastatic murine neuroblastoma tumors: role for CD8+ T cells

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Universal GFP reporter for the study of vascular development.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Multicolor fluorescence-based approaches for imaging cytokine-induced alterations in the neovascularization, growth, metastasis, and apoptosis of murine neuroblastoma tumors

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

IFN-gamma and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Core biopsies can be used to distinguish differences in expression profiling by cDNA microarrays

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Altered expression of cell cycle genes distinguishes aggressive neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Significance analysis of microarrays applied to the ionizing radiation response

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Phase I study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: a report from the Children's Oncology Group

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children's Cancer Group.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Stage and urinary catecholamine metabolite excretion in neuroblastoma. European Neuroblastoma Study Group

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Antiangiogenic strategies in neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Prospects for therapeutic inhibition of neuroblastoma angiogenesis

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Interferon-mediated anti-angiogenic therapy for neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Directional guidance of neuronal migration in the olfactory system by the protein Slit

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Induction of thrombospondin 1 by retinoic acid is important during differentiation of neuroblastoma cells

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Promotion of neurite and filopodium formation by CD47: roles of integrins, Rac, and Cdc42.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Metalloproteinases and their inhibitors in tumor angiogenesis

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

TIMP-2: an endogenous inhibitor of angiogenesis

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Enforced expression of tissue inhibitor of matrix metalloproteinase-3 affects functional capillary morphogenesis and inhibits tumor growth in a murine tumor model.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Retroviral vector-producer cell-mediated in vivo gene transfer of TIMP-3 restricts angiogenesis and neuroblastoma growth in mice

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Caspase 3 and 8 deficiency in human neuroblastoma.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Geldanamycin decreases Raf-1 and Akt levels and induces apoptosis in neuroblastomas

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Phosphatidylinositol 3-kinase inhibition down-regulates survivin and facilitates TRAIL-mediated apoptosis in neuroblastomas

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Differential regulation of protein expression, growth and apoptosis by natural and synthetic retinoids

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Targeting programmed cell death pathways with experimental therapeutics: opportunities in high-risk neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Survivin as a target for new anticancer interventions

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

7-Hydroxystaurosporine (UCN-01) preferentially sensitizes cells with a disrupted TP53 to gamma radiation in lung cancer cell lines

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Polo-like kinases and oncogenesis

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Cell-cycle targeted therapies

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Cadherins and catenins in breast cancer

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Convergence of Wnt, beta-catenin, and cadherin pathways

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Cadherins as Modulators of Cellular Phenotype

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Decorin prevents metastatic spreading of breast cancer.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Frequent low level expression in Ewing sarcoma family tumors and widespread absence of the metastasis suppressor KAI1/CD82 in neuroblastoma.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Disabled-2 inactivation is an early step in ovarian tumorigenicity

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Lats2, a putative tumor suppressor, inhibits G1/S transition

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Mechanism of induction of apoptosis by p73 and its relevance to neuroblastoma biology

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

p73-alpha is capable of inducing scotin and ER stress

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

The significance of the Wnt pathway in the pathology of human cancers

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

WNT and beta-catenin signalling: diseases and therapies

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Low expression of Wnt-5a gene is associated with high-risk neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Potent antitumor activity of interleukin-27.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Interferon-γ: an overview of signals, mechanisms and functions

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Weak HLA and beta 2-microglobulin expression of neuronal cell lines can be modulated by interferon

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Differential expression of neuronal genes defines subtypes of disseminated neuroblastoma with favorable and unfavorable outcome

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

A 6-gene signature identifies four molecular subgroups of neuroblastoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2012.664670

21 January 2018

Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of B16 melanoma metastasis by overexpression of the cysteine proteinase inhibitor cystatin C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

17q gain in neuroblastoma predicts adverse clinical outcome. U.K. Cancer Cytogenetics Group and the U.K. Children's Cancer Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irradiation of singly and doubly transduced murine neuroblastoma cells expressing B7-1 and producing interferon-gamma reduces their capacity to induce systemic immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to chemotherapy mediated by TrkB in neuroblastomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breakpoint position on 17q identifies the most aggressive neuroblastoma tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The value of serial catecholamine determinations in children with neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous liquid-chromatographic determination of 3,4-dihydroxyphenylglycol, catecholamines, and 3,4-dihydroxyphenylalanine in plasma, and their responses to inhibition of monoamine oxidase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA class I and beta 2-microglobulin expression in frozen and formaldehyde-fixed paraffin sections of neuroblastoma tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A concise guide to cDNA microarray analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retroperitoneal inoculation of murine neuroblastoma results in a reliable model for evaluation of the antitumor immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in favourable neuroblastomas is not dependent on Fas (CD95/APO-1) expression but on activated caspase 3 (CPP32)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical expression of MMP-2, MMP-9, and TIMP-2 in neuroblastoma: association with tumor progression and clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dickkopf-3/REIC functions as a suppressor gene of tumor growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catecholamine Metabolism in Neuroblastoma 1 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroblastoma and ganglioneuroblastoma: associated increased urinary excretion of catecholamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic engagement of an ineffective endogenous anti-tumor immune response and induction of IFN-gamma and Fas-ligand-dependent tumor eradication by combined administration of IL-18 and IL-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22571338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3109/07357907.2012.664670

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6993178&resulttype=core&format=json

14 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6993178&resulttype=core&format=json

14 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6993178&resulttype=core&format=json

14 May 2020

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