(Q39456888)

12 September 2017

Karyotypic Aberrations in Oncogenesis and Cancer Therapy (English)

1 reference

12 September 2017

3

Laura Senovilla

0 references

Lorenzo Galluzzi

series ordinal

5

object named as

Lorenzo Galluzzi

0 references

Guido Kroemer

series ordinal

4

object named as

Guido Kroemer

0 references

Ilio Vitale

series ordinal

1

object named as

Ilio Vitale

1 reference

12 September 2017

2

Gwenola Manic

1 reference

PubMed ID

28741522

12 September 2017

language of work or name

1 reference

1 October 2015

1 reference

12 September 2017

1 reference

12 September 2017

1

1 reference

12 September 2017

2

1 reference

12 September 2017

124-135

1 reference

Physiological significance of polyploidization in mammalian cells

12 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Gene copy-number alterations: a cost-benefit analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Limiting the proliferation of polyploid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

An immunosurveillance mechanism controls cancer cell ploidy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Illicit survival of cancer cells during polyploidization and depolyploidization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

The causes and consequences of polyploidy in normal development and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Causes and consequences of aneuploidy in cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Principles of cancer therapy: oncogene and non-oncogene addiction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Mechanisms of chromosomal instability.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

New insights into the troubles of aneuploidy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Pan-cancer patterns of somatic copy number alteration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Intratumour diversity of chromosome copy numbers in neuroblastoma mediated by on-going chromosome loss from a polyploid state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

The life history of 21 breast cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Absolute quantification of somatic DNA alterations in human cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Genome evolution during progression to breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Clonal evolution in breast cancer revealed by single nucleus genome sequencing.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

The cancer biology of whole-chromosome instability.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

A mechanism linking extra centrosomes to chromosomal instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Tumor environmental factors glucose deprivation and lactic acidosis induce mitotic chromosomal instability--an implication in aneuploid human tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Apoptosis regulation in tetraploid cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Paradoxical relationship between chromosomal instability and survival outcome in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

The spindle-assembly checkpoint and the beauty of self-destruction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Mitotic catastrophe: a mechanism for avoiding genomic instability.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Sarcoid-derived fibroblasts: links between genomic instability, energy metabolism and senescence.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Tumorigenic polyploid cells contain elevated ROS and ARE selectively targeted by antioxidant treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Cytokinesis failure triggers hippo tumor suppressor pathway activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Immunosurveillance against tetraploidization-induced colon tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Sequential cancer mutations in cultured human intestinal stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Effects of aneuploidy on cellular physiology and cell division in haploid yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Polyploidy can drive rapid adaptation in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Chromosomal duplication is a transient evolutionary solution to stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Dynamic large-scale chromosomal rearrangements fuel rapid adaptation in yeast populations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Ploidy controls the success of mutators and nature of mutations during budding yeast evolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Karyotypic determinants of chromosome instability in aneuploid budding yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Short- and long-term effects of chromosome mis-segregation and aneuploidy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Aneuploidy drives genomic instability in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Replication stress links structural and numerical cancer chromosomal instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Oncogene-like induction of cellular invasion from centrosome amplification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Chromosomal instability confers intrinsic multidrug resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Aneuploidy in health, disease, and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Metabolic targets for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Identification of aneuploidy-selective antiproliferation compounds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Aneuploid human colonic epithelial cells are sensitive to AICAR-induced growth inhibition through EGFR degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Synergistic activities of MET/RON inhibitor BMS-777607 and mTOR inhibitor AZD8055 to polyploid cells derived from pancreatic cancer and cancer stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Aneuploidy causes proteotoxic stress in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Genome-wide genetic analysis of polyploidy in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Physiological relevance of cell cycle kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Tetraploidization increases sensitivity to Aurora B kinase inhibition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Selective killing of p53-deficient cancer cells by SP600125.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Depletion of endonuclease G selectively kills polyploid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Cisplatin resistance associated with PARP hyperactivation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Cell biology. Metabolic control of cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Metabolic control of autophagy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

The causes and consequences of genetic heterogeneity in cancer evolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Tumour heterogeneity and cancer cell plasticity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Single cell sequencing reveals low levels of aneuploidy across mammalian tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

Chromothripsis from DNA damage in micronuclei.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2015.08.001

10.1016/J.TRECAN.2015.08.001

7 January 2021

Identifiers

DOI

1 reference

12 September 2017

1 reference

PubMed ID

28741522