(Q39463481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21970321%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Characterization of the cellular action of the MSK inhibitor SB-747651A (English)

1 reference

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14 February 2020

2

1 reference

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14 February 2020

Claire E McCoy

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21970321%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Simon J. Arthur

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21970321%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Shaista Naqvi

1

1 reference

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14 February 2020

Joanne Darragh

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21970321%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Alastair D Reith

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21970321%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

language of work or name

English

0 references

publication date

1 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21970321%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Biochemical Journal

1 reference

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14 February 2020

volume

441

1 reference

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14 February 2020

issue

1

1 reference

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14 February 2020

page(s)

347-357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21970321%20AND%20SRC:MED&resulttype=core&format=json

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

14 February 2020

cites work

1 reference

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Activation and signaling of the p38 MAP kinase pathway

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The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

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Targeting the mitogen-activated protein kinase cascade to treat cancer

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p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

21 January 2018

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Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

21 January 2018

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ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

21 January 2018

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MAPKAP kinases - MKs - two's company, three's a crowd

21 January 2018

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MSK1 activity is controlled by multiple phosphorylation sites.

21 January 2018

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MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts

21 January 2018

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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

21 January 2018

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The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

21 January 2018

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Generation and characterization of p38beta (MAPK11) gene-targeted mice.

21 January 2018

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MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling.

21 January 2018

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The forced swimming-induced behavioural immobility response involves histone H3 phospho-acetylation and c-Fos induction in dentate gyrus granule neurons via activation of the N-methyl-D-aspartate/extracellular signal-regulated kinase/mitogen- and st

21 January 2018

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The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation.

21 January 2018

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MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

21 January 2018

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Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators

21 January 2018

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Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins.

21 January 2018

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A coordinated phosphorylation cascade initiated by p38MAPK/MSK1 directs RARalpha to target promoters

21 January 2018

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Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

21 January 2018

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MSK1 regulates the transcription of IL-1ra in response to TLR activation in macrophages.

21 January 2018

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Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

21 January 2018

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The kinase MSK1 is required for induction of c-fos by lysophosphatidic acid in mouse embryonic stem cells

21 January 2018

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The selectivity of protein kinase inhibitors: a further update

21 January 2018

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

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Pharmacological PKA inhibition: all may not be what it seems

21 January 2018

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Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110970

Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110970

Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition

21 January 2018

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Structural bioinformatics-based design of selective, irreversible kinase inhibitors

21 January 2018

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BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

21 January 2018

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In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II

21 January 2018

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A benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor alpha production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation

21 January 2018

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(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: a novel class of potent MSK-1-inhibitors

21 January 2018

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(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: further optimisation as highly potent and selective MSK-1-inhibitors

21 January 2018

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The specificities of protein kinase inhibitors: an update

21 January 2018

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Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS.

21 January 2018

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Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells

21 January 2018

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Akt regulates growth by directly phosphorylating Tsc2

21 January 2018

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

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Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin

21 January 2018

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Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.

21 January 2018

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The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation

21 January 2018

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Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

21 January 2018

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Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7.

21 January 2018

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MSK activation and physiological roles

21 January 2018

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The many faces of H89: a review

21 January 2018

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