(Q39534943)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

New Topoisomerase I mutations are associated with resistance to camptothecin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author

Gwenaëlle Collod-Béroud

7

1 reference

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2 February 2020

Philippe Pasero

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Pierre Martineau

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Céline Gongora

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Nadia Vezzio-Vie

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Sandie Tuduri

3

1 reference

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2 February 2020

Vincent Denis

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Annick Causse

5

1 reference

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2 February 2020

Céline Auzanneau

6

1 reference

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2 February 2020

Arnaud Coquelle

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Philippe Pourquier

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Maguy Del Rio

12

1 reference

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2 February 2020

publication date

27 May 2011

1 reference

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2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

10

1 reference

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2 February 2020

page(s)

64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/1476-4598-10-64

2 February 2020

exact match

0 references

cites work

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

High resolution melting applications for clinical laboratory medicine

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Mutation of Gly721 alters DNA topoisomerase I active site architecture and sensitivity to camptothecin

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Gene expression signature in advanced colorectal cancer patients select drugs and response for the use of leucovorin, fluorouracil, and irinotecan

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Human DNA topoisomerase I: relaxation, roles, and damage control

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Repair of and checkpoint response to topoisomerase I-mediated DNA damage

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Cellular roles of dna topoisomerases: a molecular perspective

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Colorectal cancer chemotherapy: irinotecan.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Dynamic molecular combing: stretching the whole human genome for high-resolution studies.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Novel missense mutation of the DNA topoisomerase I gene in SN-38-resistant DLD-1 cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Point mutations in the topoisomerase I gene in patients with non-small cell lung cancer treated with irinotecan

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

The role of glucuronidation in 7-ethyl-10-hydroxycamptothecin resistance in vitro

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Identification of mutations at DNA topoisomerase I responsible for camptothecin resistance.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Analysis of topoisomerase I/DNA complexes in patients administered topotecan.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Camptothecin hyper-resistant P388 cells: drug-dependent reduction in topoisomerase I content.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

No alteration in DNA topoisomerase I gene related to CPT-11 resistance in human lung cancer.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Mechanisms of camptothecin resistance by human topoisomerase I mutations

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Altered serine/arginine-rich protein phosphorylation and exonic enhancer-dependent splicing in Mammalian cells lacking topoisomerase I.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Topoisomerase I inhibitors: selectivity and cellular resistance.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Gene mutation analysis and quantitation of DNA topoisomerase I in previously untreated non-small cell lung carcinomas.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120799

Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21619602

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21619602

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1476-4598-10-64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 February 2020

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1476-4598-10-64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21619602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

21619602

1 reference