(Q39723681)

14 September 2017

Interplay between MDM2, MDMX, Pirh2 and COP1: the negative regulators of p53. (English)

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14 September 2017

Lan Wang

1

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14 September 2017

Guifen He

2

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14 September 2017

Pingzhao Zhang

3

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14 September 2017

Xiang Wang

4

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14 September 2017

Mei Jiang

5

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14 September 2017

Long Yu

6

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14 September 2017

24 March 2010

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Molecular Biology Reports

14 September 2017

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14 September 2017

38

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14 September 2017

1

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14 September 2017

229-236

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https://scigraph.springernature.com/pub.10.1007/s11033-010-0099-x

14 September 2017

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cites work

Mdmx and Mdm2: brothers in arms?

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11033-010-0099-X

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

12 December 2020

Regulation of MDMX expression by mitogenic signaling

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12 December 2020

p53 Promotes proteasome-dependent degradation of oncogenic protein HBx by transcription of MDM2.

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12 December 2020

MDM2 promotes ubiquitination and degradation of MDMX

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12 December 2020

The ubiquitin ligase COP1 is a critical negative regulator of p53

1 reference

12 December 2020

Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2.

1 reference

12 December 2020

PLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53

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12 December 2020

mdm2 expression is induced by wild type p53 activity

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12 December 2020

MDMX: a novel p53-binding protein with some functional properties of MDM2

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12 December 2020

Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry?

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12 December 2020

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

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12 December 2020

COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas

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12 December 2020

Live or let die: the cell's response to p53

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12 December 2020

MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts

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12 December 2020

Mdm2 promotes the rapid degradation of p53

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12 December 2020

Hdmx stabilizes Mdm2 and p53

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12 December 2020

MdmX protects p53 from Mdm2-mediated degradation

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12 December 2020

A transcriptionally inactive E2F-1 targets the MDM family of proteins for proteolytic degradation

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12 December 2020

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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12 December 2020

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

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12 December 2020

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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12 December 2020

ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage

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12 December 2020

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

1 reference

12 December 2020

Serum p53 protein and anti-p53 antibodies are associated with increased cancer risk: a case-control study of 569 patients and 879 healthy controls

1 reference

12 December 2020

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

1 reference

12 December 2020

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

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12 December 2020

Modes of p53 regulation

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12 December 2020

MDM2 interacts with MDMX through their RING finger domains

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12 December 2020

Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer.

1 reference

12 December 2020

Control of human PIRH2 protein stability: involvement of TIP60 and the proteosome

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12 December 2020

Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene

1 reference

12 December 2020

10.1007/S11033-010-0099-X

Identifiers

DOI

1 reference

14 September 2017

1 reference