(Q39753812)

14 September 2017

Blockage of ceramide metabolism exacerbates palmitate inhibition of pro-insulin gene expression in pancreatic beta-cells (English)

1 reference

14 September 2017

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1 reference

Jun Guo

1

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14 September 2017

YingYing Qian

2

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14 September 2017

XiaoXue Xi

3

1 reference

14 September 2017

XiaoHan Hu

4

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14 September 2017

JianXi Zhu

5

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14 September 2017

Xiao Han

6

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14 September 2017

9 January 2010

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Molecular and Cellular Biochemistry

14 September 2017

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14 September 2017

338

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14 September 2017

1-2

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14 September 2017

283-290

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https://scigraph.springernature.com/pub.10.1007/s11010-009-0362-4

14 September 2017

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cites work

Signal transduction of stress via ceramide

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-009-0362-4

Protein phosphatase 2A-negative regulation of the protective signaling pathway of Ca2+/CaM-dependent ERK activation in cerebral ischemia

21 January 2018

1 reference

12 December 2020

Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

1 reference

12 December 2020

Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans

1 reference

12 December 2020

Fat storage in pancreas and in insulin-sensitive tissues in pathogenesis of type 2 diabetes

1 reference

12 December 2020

Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation

1 reference

12 December 2020

De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway

1 reference

12 December 2020

Increased skeletal muscle ceramide level in men at risk of developing type 2 diabetes

1 reference

12 December 2020

ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter

1 reference

12 December 2020

Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells

1 reference

12 December 2020

Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in beta-cells

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12 December 2020

Functional pancreatic beta-cell mass: involvement in type 2 diabetes and therapeutic intervention

1 reference

12 December 2020

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

1 reference

12 December 2020

Regulation of the insulin gene by glucose and fatty acids

1 reference

12 December 2020

Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis

1 reference

12 December 2020

Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells

1 reference

12 December 2020

Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo

1 reference

12 December 2020

Tumor necrosis factor-alpha inhibits the cardiac delayed rectifier K current via the asphingomyelin pathway

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12 December 2020

Saturated with fat: new perspectives on lipotoxicity

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12 December 2020

Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion

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12 December 2020

Role of MafA in pancreatic beta-cells

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12 December 2020

Non-esterified fatty acids are deleterious for human pancreatic islet function at physiological glucose concentration.

1 reference

12 December 2020

Evidence against the involvement of oxidative stress in fatty acid inhibition of insulin secretion

1 reference

12 December 2020

Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

1 reference

12 December 2020

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12 December 2020

Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling

1 reference

12 December 2020

Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth control

1 reference

12 December 2020

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

1 reference

12 December 2020

10.1007/S11010-009-0362-4

Identifiers

DOI

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14 September 2017

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