(Q39919544)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

Interleukin-1 receptor type 1 is a substrate for gamma-secretase-dependent regulated intramembrane proteolysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

author name string

Baukje M Elzinga

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Ciara Twomey

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

James C Powell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Frances Harte

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

language of work or name

English

0 references

publication date

7 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

26 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

1394-1409

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

Toll-like receptor signalling

26 December 2019

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice

21 January 2018

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Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway

21 January 2018

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Negative regulation of the SAPK/JNK signaling pathway by presenilin 1

21 January 2018

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21 January 2018

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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

21 January 2018

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Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein.

21 January 2018

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21 January 2018

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Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4.

21 January 2018

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

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Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors

21 January 2018

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Endoproteolytic processing and stabilization of wild-type and mutant presenilin

21 January 2018

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Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

21 January 2018

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Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels

21 January 2018

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Ubiquitination and TRAF signaling

21 January 2018

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Soluble cytokine receptors in biological therapy

21 January 2018

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Regulation of inhibitory pathways of the interleukin-1 system

21 January 2018

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Shedding light on ADAM metalloproteinases

21 January 2018

1 reference

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ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.

21 January 2018

1 reference

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Presenilin endoproteolysis is an intramolecular cleavage

21 January 2018

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Palmitoylation of the C-terminal fragment of p75(NTR) regulates death signaling and is required for subsequent cleavage by gamma-secretase

21 January 2018

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21 January 2018

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TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

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Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

21 January 2018

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Presenilin/gamma-secretase and alpha-secretase-like peptidases cleave human MHC Class I proteins

21 January 2018

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IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination

21 January 2018

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

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The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

21 January 2018

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

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SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production

21 January 2018

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21 January 2018

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gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

21 January 2018

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Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage.

21 January 2018

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Functions of toll-like receptors: lessons from KO mice

21 January 2018

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Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M803108200

Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor

21 January 2018

1 reference

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Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803108200

Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803108200

Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803108200

Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803108200

Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803108200

Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803108200

21 January 2018

Identifiers

DOI

10.1074/JBC.M803108200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference