(Q40109524)

17 September 2017

title

Hip is a pro-survival substrate of granzyme B. (English)

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17 September 2017

Daniel R Hostetter

1

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17 September 2017

Carly R K Loeb

series ordinal

2

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17 September 2017

Feixia Chu

series ordinal

3

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17 September 2017

Charles S Craik

series ordinal

4

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17 September 2017

language of work or name

English

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publication date

9 July 2007

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Journal of Biological Chemistry

17 September 2017

published in

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17 September 2017

volume

282

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17 September 2017

issue

38

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17 September 2017

page(s)

27865-27874

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Lymphocyte-mediated cytotoxicity.

17 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704312200

Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells

21 January 2018

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In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells

21 January 2018

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

21 January 2018

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The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics

21 January 2018

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A proteomic approach for the discovery of protease substrates

21 January 2018

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Identification of {alpha}-tubulin as a granzyme B substrate during CTL-mediated apoptosis

21 January 2018

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Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

21 January 2018

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Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis

21 January 2018

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Hop cleavage and function in granzyme B-induced apoptosis

21 January 2018

1 reference

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Proteolysis of HIP during apoptosis occurs within a region similar to the BID loop.

21 January 2018

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Granzyme B-induced cell death

21 January 2018

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Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis

21 January 2018

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

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Definition and redesign of the extended substrate specificity of granzyme B.

21 January 2018

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21 January 2018

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GraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences

21 January 2018

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Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways

21 January 2018

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"The stress of dying": the role of heat shock proteins in the regulation of apoptosis

21 January 2018

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Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways

21 January 2018

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Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

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Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis

21 January 2018

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21 January 2018

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The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1

21 January 2018

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The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity

21 January 2018

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Proteases universally recognize beta strands in their active sites

21 January 2018

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Nuclear BAG-1 expression inhibits apoptosis in colorectal adenoma-derived epithelial cells.

21 January 2018

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Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

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DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

21 January 2018

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The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c

21 January 2018

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Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells

21 January 2018

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Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle

21 January 2018

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Domain structure of the HSC70 cochaperone, HIP

21 January 2018

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Characterization of functional domains of the eukaryotic co-chaperone Hip

21 January 2018

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Tetratricopeptide repeat cochaperones in steroid receptor complexes

21 January 2018

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Mutational analysis of the hsp70-interacting protein Hip

21 January 2018

1 reference

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Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

21 January 2018

1 reference

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The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death

21 January 2018

1 reference

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Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704312200

Impaired Akt activity down-modulation, caspase-3 activation, and apoptosis in cells expressing a caspase-resistant mutant of RasGAP at position 157

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704312200

Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704312200

21 January 2018

Identifiers

DOI

10.1074/JBC.M704312200

1 reference

17 September 2017

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