(Q40155261)

18 September 2017

title

Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma (English)

1 reference

18 September 2017

M Maurice

3

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author name string

K Becker

series ordinal

1

1 reference

18 September 2017

N D Marchenko

series ordinal

2

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18 September 2017

U M Moll

series ordinal

4

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18 September 2017

publication date

23 March 2007

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Cell Death & Differentiation

18 September 2017

published in

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18 September 2017

volume

14

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18 September 2017

issue

7

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18 September 2017

page(s)

1350-1360

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p53 cellular localization and function in neuroblastoma: evidence for defective G(1) arrest despite WAF1 induction in MYCN-amplified cells

18 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

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OPEC/OJEC for stage 4 neuroblastoma in children over 1 year of age.

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7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Parc: a cytoplasmic anchor for p53.

1 reference

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7 January 2021

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Cytoplasmically "sequestered" wild type p53 protein is resistant to Mdm2-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

The Ews/Fli-1 fusion gene changes the status of p53 in neuroblastoma tumor cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Evidence that wild-type p53 in neuroblastoma cells is in a conformation refractory to integration into the transcriptional complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

C-terminal ubiquitination of p53 contributes to nuclear export

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

The MDM2 RING-finger domain is required to promote p53 nuclear export

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Tumour suppression: disruption of HAUSP gene stabilizes p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

A dynamic role of HAUSP in the p53-Mdm2 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

p53 and Nur77/TR3 - transcription factors that directly target mitochondria for cell death induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Increased frequency of aberrations in the p53/MDM2/p14(ARF) pathway in neuroblastoma cell lines established at relapse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Nuclear degradation of p53 occurs during down-regulation of the p53 response after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Recognition of the polyubiquitin proteolytic signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Identification of p53 sequence elements that are required for MDM2-mediated nuclear export

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Monoubiquitylation promotes mitochondrial p53 translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

The HAUSP gene plays an important role in non-small cell lung carcinogenesis through p53-dependent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402126

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402126

1 reference

Dimensions Publication ID

18 September 2017

1043928256

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1 reference