(Q40184763)

18 September 2017

YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia (English)

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18 September 2017

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Sun HL

1

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18 September 2017

Liu YN

2

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18 September 2017

Huang YT

3

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18 September 2017

Pan SL

4

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18 September 2017

Huang DY

5

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18 September 2017

Guh JH

6

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18 September 2017

Lee FY

7

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18 September 2017

Kuo SC

8

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18 September 2017

Teng CM

9

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18 September 2017

language of work or name

English

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publication date

8 January 2007

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18 September 2017

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18 September 2017

26

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18 September 2017

27

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18 September 2017

3941-3951

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210169

18 September 2017

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cites work

Growth and survival mechanisms associated with perineural invasion in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

The subtle side to hypoxia inducible factor (HIFalpha) regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Exploiting tumour hypoxia in cancer treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Activation of nuclear factor-kappaB in human prostate carcinogenesis and association to biochemical relapse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

NF-kappaB plays a key role in hypoxia-inducible factor-1-regulated erythropoietin gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Nuclear Factor- B Nuclear Localization Is Predictive of Biochemical Recurrence in Patients with Positive Margin Prostate Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Regulation of phosphoglucose isomerase/autocrine motility factor expression by hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Induction of mitotic arrest and apoptosis in human prostate cancer pc-3 cells by evodiamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Aryl hydrocarbon nuclear translocator (ARNT) promotes oxygen-independent stabilization of hypoxia-inducible factor-1alpha by modulating an Hsp90-dependent regulatory pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Pyrrolidine dithiocarbamate and zinc inhibit proteasome-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Suppression of tumor growth through disruption of hypoxia-inducible transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

NF-κB nuclear localization and its prognostic significance in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Wortmannin inhibits activation of nuclear transcription factors NF-kappaB and activated protein-1 induced by lipopolysaccharide and phorbol ester

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Targeting multiple signaling pathways as a strategy for managing prostate cancer: multifocal signal modulation therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Caffeic acid phenethyl ester-induced PC-3 cell apoptosis is caspase-dependent and mediated through the loss of inhibitors of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Mdm2 and HIF-1alpha interaction in tumor cells during hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Expression of nuclear factor-kappa B and I kappa B alpha proteins in prostatic adenocarcinomas: correlation of nuclear factor-kappa B immunoreactivity with disease recurrence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Hypoxia-inducible factor 1alpha and 1beta proteins share common signaling pathways in human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Functional integrity of nuclear factor kappaB, phosphatidylinositol 3'-kinase, and mitogen-activated protein kinase signaling allows tumor necrosis factor alpha-evoked Bcl-2 expression to provoke internal ribosome entry site-dependent translation of

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaB-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210169

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210169

1 reference

Dimensions Publication ID

18 September 2017

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1 reference